Abstract: The present invention relates to a device and method for extracting physiological information from electromagnetic radiation emitted or reflected by a subject (12). A data stream (30) derived from detected electromagnetic radiation is received, the data stream (30) comprising a first sequence (92; 152) of signal samples (94) indicative of various spectral portions. The data stream (30) is split into at least two deduced staggered sequences (96a, 96b, 96c) of registered signal samples (94a, 94b, 94c), wherein each of the deduced staggered sequences (96a, 96b, 96c) represents a defined spectral portion (82a, 82b, 82c) and comprises indicative signal samples (94a, 94b, 94c) spaced in time. Artificial samples (102a, 2b, 102c) are generated under consideration of proximate indicative signal samples (94a, 94b, 94c) so as to at least partially replace blank spaces (98) between the indicative signal 10 samples (94a, 94b, 94c), thereby generating a supplemented data stream (106).