Abstract: The present invention provides methods of diagnosis and prognosis of human chronic lymphocytic leukemia (CLL) in a subject a patient in need thereof. The methods of the present invention involve measuring the expression profile of two known genes: LPL and ADAM29; and comparing the ratio of their expression to diagnose the presence of CLL or to prognose the likelihood of developing CLL or the symptoms consistent with CLL.

Abstract: The present invention provides methods of diagnosis and prognosis of human chronic lymphocytic leukemia (CLL) in a patient in need thereof and methods to determine IgVH mutational status. The methods of the present invention involve measuring the expression profile of two known genes: LPL and ADAM29; and comparing the ratio of their expression to diagnose the presence of CLL or to prognose the likelihood of developing CLL or the symptoms consistent with CLL.

Abstract: The present invention provides methods of diagnosis and prognosis of human chronic lymphocytic leukemia (CLL) in a subject a patient in need thereof. The methods of the present invention involve measuring the expression profile of two known genes: LPL and ADAM29; and comparing the ratio of their expression to diagnose the presence of CLL or to prognose the likelihood of developing CLL or the symptoms consistent with CLL.

Abstract: The present invention provides methods of diagnosis and prognosis of human chronic lymphocytic leukemia (CLL) in a subject a patient in need thereof. The methods of the present invention involve measuring the expression profile of two known genes: LPL and ADAM29; and comparing the ratio of their expression to diagnose the presence of CLL or to prognose the likelihood of developing CLL or the symptoms consistent with CLL.

Abstract: A process for the manufacture of a sheet, band or strip of zirconium alloy or hafnium alloy, comprising hot roughing of an ingot into a blank, then hot rolling of this blank in the alpha domain, this hot rolling including several passes which follow one or more reheatings in a furnace at one or more temperatures (TR), each of which improves the formability of this blank, then cold rolling which consists of one or more cycles of rolling pinch passing/heat treatment. The hot rolling pass following the last furnace reheating is followed by reheating of the hot rolled blank by at least 100.degree. C. at more than 4.degree. C./s by infrared heating means with a wavelength between 0.8 and 5 micrometers. The hot rolling is then continued until the thickness at the end of the hot rolling is less than or equal to 0.8 times the thickness of the hot rolled blank. The product obtained is used for the manufacture of zirconium or hafnium alloy parts for water-type nuclear reactors.

Abstract: A process for the manufacture of a flat product of zirconium alloy having a width between 50 and 600 mm from a flat cold rolled product. The cold rolled product is heated to the beta range and maintained in the beta range using an infra-red heating device with a wavelength of between 0.8 and 5 microns, the maximum temperature difference over the width of the product being less than 35.degree. C. The product is then rapidly cooled and optionally annealed to obtain a flat product, which can be a strip, sheet or band.

Abstract: In a bicycle frame comprising a plurality of tubes having hollow ends and a plurality of fittings having pins fitting in the hollow ends, each pin extends along an axis and has an outer surface portion of axially constant section centered on the axis and engaged in the respective tube end, an inner surface portion centered on the axis and flaring axially inward away from the inner end of the respective outer surface portion, and a shoulder surface projecting generally perpendicular from the inner end of the respective inner surface portion and facing outward. Each tube end has an end surface abutting flatly inward on the respective shoulder surface and an inner surface having an inner surface portion fitted tightly over and complementary to the inner surface portion of the respective pin and an outer surface portion radially slightly spaced from and facing the outer surface portion of the respective pin.

Abstract: An apparatus for heating or cooling sealed food pouches, another apparatus for moving the same and a third apparatus adapted to transfer the pouches are disclosed. The three apparatuses are designed to function as an integrated food pouch handling system, but may also be used separately. The first apparatus consists of a large bath partially filled with circulating hot or cold liquid, following a course in which whirlpools are created. The food pouches are placed in the bath and are carried by the moving liquid until they have attained the desired temperature. The second apparatus consists of a conveyor mounted on a cart. The conveyor is tiltable so that one end thereof can be placed in the bath to automatically retrieve the food pouches. The third apparatus is a large vat to receive the food pouches placed therein by the conveyor.

Abstract: Continuous process for the production of monochloroacetyl chloride accompanied, if the need should arise, by monochloroacetic acid, from trichloroethylene and/or 1,1,1,2-tetrachloroethane by reaction for hydration of trichloroethylene and/or 1,1,1,2-tetrachloroethane under pressure of hydrogen chloride in liquid phase, in the presence of ferric chloride in partial suspension.