Abstract: Herein are described the preparation of a series of synthetic rocaglates, amidino- and amino-rocaglates, which display inhibition of protein translation and tumor cell proliferation (in vitro and in vivo). The methods described herein allow the preparation of libraries of modified rocaglates. This chemical modification of the rocaglate scaffold changes the C8b-hydroxyl of the natural product series to a more optimal hydrogen bond donor/acceptor.

Abstract: Embodiments disclosed herein relate to methods and apparatus to inhibit rotation within a drilling rig. The apparatus may include a first member connected to a first component of the drilling rig, and a second member connected to the first member and connected to a second component of the drilling rig, the second component configured to move vertically with respect to the first component. The first member is configured to move vertically with respect to the second member and the first member and the second member substantially inhibit rotation between each other. The apparatus may include a rotational adjustment system, in which the rotational adjustment system is used to connect with one of the components of the drilling rig.

Abstract: Embodiments disclosed herein relate to methods and apparatus to inhibit rotation within a drilling rig. The apparatus may include a first member connected to a first component of the drilling rig, and a second member connected to the first member and connected to a second component of the drilling rig, the second component configured to move vertically with respect to the first component. The first member is configured to move vertically with respect to the second member and the first member and the second member substantially inhibit rotation between each other. The apparatus may include a rotational adjustment system, in which the rotational adjustment system is used to connect with one of the components of the drilling rig.

Abstract: Embodiments disclosed herein relate to methods and apparatus to inhibit rotation within a drilling rig. The apparatus may include a first member connected to a first component of the drilling rig, and a second member connected to the first member and connected to a second component of the drilling rig, the second component configured to move vertically with respect to the first component. The first member is configured to move vertically with respect to the second member and the first member and the second member substantially inhibit rotation between each other. The apparatus may include a rotational adjustment system, in which the rotational adjustment system is used to connect with one of the components of the drilling rig.

Abstract: Embodiments disclosed herein relate to methods and apparatus to inhibit rotation within a drilling rig. The apparatus may include a first member connected to a first component of the drilling rig, and a second member connected to the first member and connected to a second component of the drilling rig, the second component configured to move vertically with respect to the first component. The first member is configured to move vertically with respect to the second member and the first member and the second member substantially inhibit rotation between each other. The apparatus may include a rotational adjustment system, in which the rotational adjustment system is used to connect with one of the components of the drilling rig.

Abstract: An improved gate lock provides for easy engagement and allows for a high degree of variability of the orientation and position of the mating portions of the lock. The lock includes a lock pin movably retained in a base. The pin coordinates with, and engages, a latch in a separate receiver to provide a physical lock. The latch is spring-mounted in a locked position to allow it to slide laterally within the receiver to receive and capture the pin during the locking function. The receiver includes a pin slot or opening having an angled surface for directing the pin into the latch for easier movement and engagement. The latch has an angled or curved strike surface on which the pin slides during locking. A solenoid is mounted to the receiver and is connected to the latch to provide for automatic withdrawal of the latch for unlocking functions.

Abstract: Methods and apparatus are provided for a shield to protect a surface from the impact of hyper-velocity projectiles. The apparatus comprises a foam material that is configured to cover the surface to be protected and is attached directly to that surface. A coating material is typically disposed on the outer surface of the foam material and may penetrate the foam material to a predetermined depth. The foam material and the coating material are selected to form a composite having predetermined values of sonic velocity, toughness, and thermal conductivity. The composite of foam material and coating material can be significantly lighter in weight than a metal shield having equivalent protective characteristics.

Abstract: A collimator filter for a physical vapor deposition apparatus useful for coating semiconductor wafers includes a plurality of corrugated ribbons attached at abutting double-walled nodes by resistance spot welding. The nodes are sealed by application of a braze material to diverging wall portions of the nodes by extrusion or spraying, followed by heating in a vacuum furnace. Alternatively, the nodes may be sealed by application of a braze material foil to a top and a bottom surface of the collimator followed by heating in the vacuum furnace. By sealing the nodes, a significant reduction may be achieved in outgassing and generation of particulate contaminants.

Abstract: This process for enriching nickel-bearing oxide ore comprises pulping the ore, washing the pulped ore for at least 1 minute, sorting the washed ore in a damp environment so as to separate at least one fine fraction from a granular fraction, subjecting the fine fraction to densimetric separation at a dividing density of between 1.7 and 2.5 and recovering the light fraction separated off as enriched ore.