Abstract: The invention relates to a method for purifying biologically active GLA-domain coagulation proteins, comprising the following steps: a) bringing a sample that contains one or more GLA-domain coagulation proteins and may contain biologically inactive molecules of GLA-domain protein(s), into contact with an affinity support on which nucleic aptamers that bind specifically to at least one biologically active GLA-domain coagulation protein are immobilized, in order to form complexes between (i) said nucleic aptamers and (ii) said GLA-domain coagulation protein(s), b) releasing the GLA-domain coagulation protein(s) from the complexes formed in step a), and c) recovering said biologically active GLA-domain coagulation protein(s) in a purified form.

Abstract: The invention relates to a method for purifying biologically active GLA-domain coagulation proteins, comprising the following steps: a) bringing a sample that contains one or more GLA-domain coagulation proteins and may contain biologically inactive molecules of GLA-domain protein(s), into contact with an affinity support on which nucleic aptamers that bind specifically to at least one biologically active GLA-domain coagulation protein are immobilized, in order to form complexes between (i) said nucleic aptamers and (ii) said GLA-domain coagulation protein(s), b) releasing the GLA-domain coagulation protein(s) from the complexes formed in step a), and c) recovering said biologically active GLA-domain coagulation protein(s) in a purified form.

Abstract: A a method for purifying biologically active GLA-domain coagulation proteins, includes the following steps: a) bringing a sample that contains one or more GLA-domain coagulation proteins and may contain biologically inactive molecules of GLA-domain protein(s), into contact with an affinity substrate on which nucleic aptamers that bind specifically to at least one biologically active GLA-domain coagulation protein are immobilized, in order to form complexes between (i) the nucleic aptamers and (ii) the GLA-domain coagulation protein(s), b) releasing the GLA-domain coagulation protein(s) from the complexes formed in step a), and c) recovering the biologically active GLA-domain coagulation protein(s) in a purified form.

Abstract: A method for purifying biologically active GLA-domain coagulation proteins, includes the following steps: a) bringing a sample that contains one or more GLA-domain coagulation proteins and may contain biologically inactive molecules of GLA-domain protein(s), into contact with an affinity substrate on which nucleic aptamers that bind specifically to at least one biologically active GLA-domain coagulation protein are immobilized, in order to form complexes between (i) the nucleic aptamers and (ii) the GLA-domain coagulation protein(s), b) releasing the GLA-domain coagulation protein(s) from the complexes formed in step a), and c) recovering the biologically active GLA-domain coagulation protein(s) in a purified form.

Abstract: A dental tool for retracting gingival tissue is provided that includes a shaft and a working end member, the working end member having an operative end including a first portion sufficiently narrow to retract tissue from a groove of a tooth and a second portion, adjacent the first portion, and being sufficiently wide to retract tissue from an area of the tooth adjacent the groove. A method for retracting gingival tissue is also disclosed.

Abstract: The present invention provides peptides which can interact with VEGF and inhibit VEGF interaction with KDR or anti-VEGF antibody thereby inhibiting VEGF mediated angiogenesis or angiogeneis related diseases, polynucleotide encoding the peptides, vectors containing the polynucleotides, pharmaceutical compositions containing the peptides, and methods of inhibiting angiogenesis with the peptides.

Abstract: The present invention provides peptides which can interact with VEGF and inhibit VEGF interaction with KDR or anti-VEGF antibody thereby inhibiting VEGF mediated angiogenesis or angiogeneis related diseases, polynucleotide encoding the peptides, vectors containing the polynucleotides, pharmaceutical compositions containing the peptides, and methods of inhibiting angiogenesis with the peptides.

Abstract: The present invention provides peptides which can interact with VEGF and inhibit VEGF interaction with KDR or anti-VEGF antibody thereby inhibiting VEGF mediated angiogenesis or angiogeneis related diseases, polynucleotide encoding the peptides, vectors containing the polynucleotides, pharmaceutical compositions containing the peptides, and methods of inhibiting angiogenesis with the peptides.

Abstract: This machine for wet treatment, for example dyeing, for textile materials, comprises a horizontally elongate vat, in which is formed a zone for the storage in folds of the fabric to be treated, which forms a rope closed on itself. A hydraulic and/or mechanical system for driving the fabric is placed at the start of a transport tube provided for returning the fabric from the front end of the vat toward the rear end of the latter. A system for injecting a gas stream, for example air, in contact with the fabric is provided within the vat; the system is located, in the direction of travel of the fabric, between the point where this fabric returns to the storage zone and the hydraulic system. This system spreads and dries the fabric. The invention is used for the fault-free dyeing of fabrics composed of modern fibers.

Abstract: The present invention provides peptides which can interact with VEGF and inhibit VEGF interaction with KDR or anti-VEGF antibody thereby inhibiting VEGF mediated angiogenesis or angiogeneis related diseases, polynucleotide encoding the peptides, vectors containing the polynucleotides, pharmaceutical compositions containing the peptides, and methods of inhibiting angiogenesis with the peptides.

Abstract: A device and system for releasably securing a watchband to a watch casing. Specifically, a watchband connector pin is formed of a shape memory material, preferably a shape memory alloy. The watchband may be readily released and reattached from a watch casing to facilitate repairs of the watch, for aesthetic considerations, or when the watch band is damaged or worn. The connector pin is durable due to the one piece design, easy to operate, flexible, and economical to produce.

Abstract: A disposable orthodontic bracket pad. The bracket pad comprises a top and a bottom sheet, wherein the top sheet is made of an inexpensive liquid-impermeable material and has a plurality of openings defining bracket staging areas, and a bottom sheet made of an inexpensive material having one side coated with an adhesive material. The bracket staging areas are preferably arranged in the shape of an arch to mimic the arrangement of teeth and facilitate bracket identification. The bottom sheet is adhered to the top sheet via said adhesive materials, forming a bracket pad having adhesive bracket staging areas. The bracket pad is preferably less than 1/8 of an inch in thickness.

Abstract: A disposable marking device particularly suited for marking wires used in orthodontic treatment is disclosed, comprising a shaft made of metal, plastic, paper, wood, or any other material of suitable stiffness, preferably about the size of a toothpick, coated on at least one end with a pigmented binder, preferably a wax or polymer based material, capable of marking metal wires. A method for marking an orthodontic wire is also disclosed.