Abstract: The disclosure relates to the use of a proteolytic enzyme substrate of general formula: Q1-Xaa2-Xaa1-rhodamine110-Q2, in which: Xaa1 and Xaa2 are amino acids and Q2 is a group comprising an alkyl group; so as to be able to allow, in a blood sample containing a glycosaminoglycan, said glycosaminoglycan to inhibit the coagulation of said blood sample, via which the anticoagulant capacity of the glycosaminoglycan is not disrupted.

Abstract: The disclosure relates to the use of a proteolytic enzyme substrate of general formula: Q1-Xaa2-Xaa1-rhodamine110-Q2, in which Xaa1 and Xaa2 are amino acids and Q2 is Xaa1-Xaa2-Q1, or an amino acid Xaa3, or a group comprising an aryl group, or H, so as to be able to inhibit, in a blood sample containing a glycosaminoglycan, the anticoagulant capacity of said glycosaminoglycan. The invention also relates to a method for measuring an enzymatic activity using such a substrate and a kit for implementation thereof.

Abstract: The invention relates to chromogenic compounds and the use thereof for the determination of enzymes of the family of carboxypeptidases N and carboxypeptidases U. The above is more specifically a compound of formula (I) in which A=(1), (2), (3), (4) or (5), R1, R2=H, —CH3, —CH(CH3)2, —OCH3, —Cl,—CF3,—OCF3,—SCH3, R3=an amino acid group which may be hydrolysed by a carboxypeptidase A and R4=a basic amino acid group.

Abstract: The invention concerns contact activators for the endogenous coagulation pathway and their use in exploring coagulation anomalies. The activators of the invention are derivatives of gallic acid, preferably polyethylene glycol gallates.

Abstract: A wall molding for suspended ceiling systems has a self-aligning feature adapted to locate one end of a piece being installed on the end of a previously installed piece so that an installation of high quality workmanship is quickly obtained. The self-aligning feature is in the form of a tongue extending longitudinally beyond a faux end and adapted to nest in the previously installed piece. The tongue fits within the spaces between hems on the longitudinal edges of legs of a right angle cross-section and the opposed legs so that the tongue is laterally restrained in the planes of the legs and is longitudinally restrained by abutting end edges.

Abstract: The invention relates to chromogenic compounds and the use thereof for the determination of enzymes of the family of carboxypeptidases N and carboxypeptidases U. The above is more specifically a compound of formula (I) in which A=(1), (2), (3), (4) or (5). R1. R2=H. —CH3, —CH(CH3)2, —OCH3, —Cl.—CF3,—OCF3,—SCH3, R3=an amino acid group which may be hydrolysed by a carboxypeptidase A and R4=a basic amino acid group.

Abstract: The invention concerns a compound exhibiting an anti-heparin activity, of formula ZBm?(AXA)xBn?(AXA)yBo(AXA)zBp, the diagnostic reagents comprising it and the use of said compound in an in vitro diagnostic test of a medicine for anti-heparin activity.

Abstract: The invention concerns a compound exhibiting an anti-heparin activity, of formula Z Bm ! (AXA)x Bn ! (AXA)y Bo (AXA)z Bp, the diagnostic reagents comprising it and the use of said compound in an in vitro diagnostic test of a medicine for anti-heparin activity.

Abstract: The invention concerns contact activators for the endogenous coagulation pathway and their use in exploring coagulation anomalies.

Abstract: Peptide substrates selected from the group consisting of (i) the tri- and tetra-peptides of the formulaQ-A.sub.1 -A.sub.2 -Gly-A.sub.4 -R (I)having SEQ ID NO: 1 in which Q is a group which blocks the N-termnal end of the peptide chain, A.sub.1 is selected from the group consisting of Leu, Ile, Nle, Nva, CHA, CHG, CHT, Phe, Ala and Lys groups, where the basic side-group of the Lys residue is blocked with a suitable group which substantially removes the basic character of said side-group, A.sub.2 is a single bond, Asp or Glu, the carboxylic acid side-group of Asp and Glu being capable of esterification or amidation, A.sub.4 is selected from the group consisting of Arg and Lys groups, and R is pNA; and (ii) their addition salts. These peptide substrates are useful in the determination of Factor Xa.

Abstract: The present invention relates to a method of determining, assaying and identifying strains of Candida and pathogenic strains belonging to species Torulopsis glabrata by means of chromogenic substrates of monoamino acid or peptide type without the isolation of the strains to be identified.

Abstract: The present invention relates, by way of novel industrial products, to peptide compounds selected from the group consisting of(i) the tripeptides of the formulaY--A.sub.1 --A.sub.2 --A.sub.3 --R (I)in whichY is H or an appropriate group blocking the N-terminal end,A.sub.1 is an amino acid residue selected from the group consisting of (2-oxothiazolidin-4-yl)carbonyl [abbreviated to THC], (2-oxotetrahydro-1,3-thiazin-5yl)carbonyl [abbreviated to TZC], thiazolidine-4-carbonyl [abbreviated to ATC] and (tetrahydro-1,3-thiazin-5-yl)carbonyl [abbreviated to AZC] residues,A.sub.2 is an amino acid residue selected from the group consisting of Pro, 3Hyp and 4Hyp residues, where the OH side-group of 3Hyp and 4Hyp is capable of being protected by an ether or ester protecting group,A.sub.3 is an amino acid residue selected from the group consisting of Arg and Lys residues, andR is a labeling means; and(ii) their addition salts.These novel compounds are useful as substrates in the determination of Protein C.

Abstract: The new invention relates, by way of novel industrial products, to compounds selected from(i) the symmetrical amino acids and peptides of the formulaR--A--B--CO--Q--CO--B--A--R (I)in whichQ is a polyalkylene glycol residue selected from the polyethylene glycol and polypropylene glycol residues of the formula--O[CH(X)CH.sub.2 O]--in which X is H or Me and n is an integer greater than or equal to 1,B is a single bond, a monoamino acid residue or a peptide chain comprising from 2 to 9 monoamino acid residues,A is a basic monoamino acid residue selected from the group consisting of .alpha.-amino acid residues containing a basic group on a side-chain, andR is a labeling means making it possible to develop the enzyme substance to be identified or assayed; and(ii) their addition salts.These novel compounds are useful as substrates for the assay of enzymes, especially proteases and peptidases.