Patents by Inventor Gerard Rosse

Gerard Rosse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SULFONE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS
    Publication number: 20220274922
    Abstract: Provided herein are sulfone compounds, for example, a compound of Formula A, or an enantiomer, a mixture of enantiomers, a mixture of two or more diastereomers, a tautomer, a mixture of two or more tautomers, or an isotopic variant thereof; or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof; and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a disorder, disease, or condition.
    Type: Application
    Filed: July 10, 2020
    Publication date: September 1, 2022
    Inventors: Nazneen Dewji, Darryl Rideout, Gerard Rosse
  • Compounds useful as chemokine receptor antagonists
    Patent number: 8399455
    Abstract: The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions for the inhibition of Chemokine Receptors and also for the treatment of various diseases, conditions, or disorders, including acute or chronic inflammatory disease, cancer, and osteolytic bone disorders.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: March 19, 2013
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Gerard Rosse, Linli Wei, Kenneth G. Carson
  • COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS
    Publication number: 20100234356
    Abstract: The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions for the inhibition of Chemokine Receptors and also for the treatment of various diseases, conditions, or disorders, including acute or chronic inflammatory disease, cancer, and osteolytic bone disorders.
    Type: Application
    Filed: October 13, 2009
    Publication date: September 16, 2010
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Gerard Rosse, Linli Wei, Kenneth G. Carson
  • Compounds useful as chemokine receptor antagonists
    Patent number: 7635698
    Abstract: The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions for the inhibition of Chemokine Receptors and also for the treatment of various diseases, conditions, or disorders, including acute or chronic inflammatory disease, cancer, and osteolytic bone disorders.
    Type: Grant
    Filed: December 28, 2005
    Date of Patent: December 22, 2009
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Gerard Rosse, Linli Wei, Kenneth G. Carson
  • Substituted diaryl heterocycles, process for their preparation and their use as medicaments
    Patent number: 7141561
    Abstract: This invention discloses and claims diary heterocycles of formula (I) and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using said compounds of formula (I) for the treatment or prevention of excessive weight or obesity, and for treatment of Type II diabetes, arteriosclerosis, high blood pressure, depression, anxiety, anxiety neuroses, and schizophrenia. Methods for treatment of excessive weight or obesity and for treatment of Type II diabetes with a mixture of a compound of formula I and antiobesity agents or appetite-regulating active ingredients, or with a mixture of a compound of formula I and antidiabetics or hypoglycemic active ingredients are also disclosed and claimed.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: November 28, 2006
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Thomas Boehme, Gerhard Hessler, Gerard Rosse, Armin Walser
  • Compounds useful as chemokine receptor antagonists
    Publication number: 20060189628
    Abstract: The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions for the inhibition of Chemokine Receptors and also for the treatment of various diseases, conditions, or disorders, including acute or chronic inflammatory disease, cancer, and osteolytic bone disorders.
    Type: Application
    Filed: December 28, 2005
    Publication date: August 24, 2006
    Inventors: Gerard Rosse, Linli Wei, Kenneth Carson
  • Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals
    Publication number: 20040198733
    Abstract: The present invention relates to aminoalkyl-substituted aromatic bicyclic compounds of formula I, 1
    Type: Application
    Filed: April 9, 2004
    Publication date: October 7, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Armin Walser, Gerard Rosse
  • Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals
    Publication number: 20040198731
    Abstract: The present invention relates to aminoalkyl-substituted aromatic bicyclic compounds of formula I, 1
    Type: Application
    Filed: April 9, 2004
    Publication date: October 7, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Armin Walser, Gerard Rosse
  • Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals
    Publication number: 20040198732
    Abstract: The present invention relates to aminoalkyl-substituted aromatic bicyclic compounds of formula I, 1
    Type: Application
    Filed: April 9, 2004
    Publication date: October 7, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Armin Walser, Gerard Rosse
  • Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals
    Publication number: 20040192693
    Abstract: The present invention relates to aminoalkyl-substituted aromatic bicyclic compounds of formula I, 1
    Type: Application
    Filed: April 9, 2004
    Publication date: September 30, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Armin Walser, Gerard Rosse
  • Substituted diaryl heterocycles, process for their preparation and their use as medicaments
    Publication number: 20040132752
    Abstract: This invention discloses and claims diary heterocycles of formula (I) 1
    Type: Application
    Filed: July 24, 2003
    Publication date: July 8, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Thomas Boehme, Gerhard Hessler, Gerard Rosse, Armin Walser