Patents by Inventor Gerard Ulibarri

Gerard Ulibarri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of amidines, their preparation, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7576241
    Abstract: A compound of the formula wherein the substituents are defined as in the specification useful as intermediates.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: August 18, 2009
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Serge Auvin, Pierre-Etienne Chabrier de Lassauniere, Jeremiah Harnett, Dominique Pons, Gerard Ulibarri
  • Derivatives of amidines, their preparation, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7473779
    Abstract: Novel derivatives of amidines of formula wherein the substituents are defined as in the specification which are useful for inhibiting activity on NO-synthase enzymes producing nitrogen mono oxide and/or trapping the reactive oxygen species (ROS) making them useful for treating various diseases.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: January 6, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Serge Auvin, Pierre-Etienne Chabrier de Lassauniere, Jeremiah Harnett, Dominique Pons, Gérard Ulibarri
  • Derivatives of N-(iminomethyl)amines, their preparation, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7186752
    Abstract: N-(imino)amines and their preparation and their use as NO synthase inhibitors and selective or non-selective traps for a reactive oxygen species.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: March 6, 2007
    Assignee: SCRAS
    Inventors: Dennis Bigg, Pierre-Etienne Chabrier de Lassauniere, Serge Auvin, Jeremiah Harnett, Gérard Ulibarri
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7135478
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: November 14, 2006
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gérard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7053102
    Abstract: Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring ?-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification sufficient to treat cancer.
    Type: Grant
    Filed: June 7, 2004
    Date of Patent: May 30, 2006
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • New derivatives of amidines, their preparation, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20060084667
    Abstract: Compounds of the formula wherein the substituents are as defined in the specification useful as intermediates.
    Type: Application
    Filed: October 14, 2005
    Publication date: April 20, 2006
    Inventors: Serge Auvin, Pierre-Etienne Chabrier de Lassauniere, Jeremiah Harnett, Dominique Pons, Gerard Ulibarri
  • Derivatives of N-(iminomethyl)amines, their preparation, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20050197329
    Abstract: N-(imino)amines and their preparation and their use as NO synthase inhibitors and selective or non-selective traps for a reactive oxygen species.
    Type: Application
    Filed: April 26, 2005
    Publication date: September 8, 2005
    Inventors: Dennis Bigg, Pierre-Etienne Chabrier de Lassauniere, Serge Auvin, Jeremiah Harnett, Gerard Ulibarri
  • New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20050038064
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Application
    Filed: August 31, 2004
    Publication date: February 17, 2005
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • New derivatives of N-(iminomethyl)amines, their preparation, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20050027009
    Abstract: N-(imino)amines and their preparation and their use as NO synthase inhibitors and selective or non-selective traps for a reactive oxygen species.
    Type: Application
    Filed: July 21, 2004
    Publication date: February 3, 2005
    Inventors: Dennis Bigg, Pierre-Etienne Chabrier de Lassauniere, Serge Auvin, Jeremiah Harnett, Gerard Ulibarri
  • New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20040254163
    Abstract: Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring &bgr;-hydroxy lactone ring of the formula 1
    Type: Application
    Filed: June 7, 2004
    Publication date: December 16, 2004
    Applicant: SOCIETE DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6815546
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: November 9, 2004
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gérard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Derivatives of N-(iminomethy)amines, their preparation, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6809090
    Abstract: N-(imino)amines and their preparation and their use as NO synthase inhibitors and selective or non-selective traps for a reactive oxygen species.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: October 26, 2004
    Inventors: Dennis Bigg, Pierre-Etienne Chabrier de Lassauniere, Serge Auvin, Jeremiah Harnett, Gérard Ulibarri
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6797715
    Abstract: A method of treating a cancer in warm-blooded animals by administration to the warm-blooded animals in need thereof a camptothecin analog a 7-ring member &bgr;-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: September 28, 2004
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • 2-aminopyridine derivatives, their use as medicines and pharmaceutical compositions containing them
    Patent number: 6762176
    Abstract: The invention concerns novel 2-aminopyridine derivatives having an activity inhibiting NO-synthase enzymes producing nitrogen monoxide NO and/or trapping reactive forms of oxygen, the methods for preparing them, pharmaceutical compositions containing them and their therapeutic uses, particularly their use as NO-synthase inhibitors and for trapping reactive forms of oxygen whether selectively or not.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: July 13, 2004
    Assignee: Societe de Consells de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Pierre-Etienne Chabrier de Lassauniere, Serge Auvin, Jerry Harnett, Dominique Pons, Gérard Ulibarri, Dennis Bigg
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6762301
    Abstract: A process for the preparation of a compound of the formula wherein the substituents are defined as set forth in the specification comprising reacting a compound of the formula with a 2-halo-3-quinoline-methanol of the formula to obtain a compound of the formula which is then cyclized to form the compound of Formula I.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: July 13, 2004
    Assignee: Societe de Conseils de Recherches et Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • New derivatives of N-(iminomethy)amines, their preparation, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20040097494
    Abstract: N-(imino)amines and their preparation and their use as NO synthase inhibitors and selective or non-selective traps for a reactive oxygen species.
    Type: Application
    Filed: July 1, 2003
    Publication date: May 20, 2004
    Applicant: SOCIETE DE CONSEILS DE RECHERCHES D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
    Inventors: Dennis Bigg, Pierre-Etienne de Lassunier Chabrier, Serge Auvin, Jeremiah Harnett, Gerard Ulibarri
  • Derivatives of 2-aminopyridines, their use as medicaments and pharmaceutical compositions containing them
    Patent number: 6727239
    Abstract: A compound of the formula wherein the substituents are defined as in the specification and their pharmaceutically acceptable salts having NOS and ROS activity.
    Type: Grant
    Filed: April 2, 2003
    Date of Patent: April 27, 2004
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Pierre-Etienne Chabrier de Lassauniere, Serge Auvin, Jerry Harnett, Dominique Pons, Gérard Ulibarri, Dennis Bigg
  • Cyclin-dependent kinase (cdk) and glycolene synthase kinase-3 (gsk-3) inhibitors
    Publication number: 20040048849
    Abstract: The invention concerns novel cyclin-dependent kinase (CDK) and glycolene synthase kinase-3 (GSK-3) inhibitors, corresponding to general formula (I), wherein: A represents a hydrogen atom, a halogen atom, a formyl, cyano, nitro, guanidinoaminomethylenyl, (1,3-dihydro-2-oxoindol)-3-ylidenemethyl, alkylcarbonyl, aralkylcarbonyl or heteroaralkylcarbonyl radical, or a -L-NR1R2 radical wherein L represents an alkylene radical and R1 and R2 are selected independently among a hydrogen atom and an alkyl radical or R1 and R2 together with the nitrogen bearing them form a heterocycle with 5 to 7 members optionally substituted; X represents a hydrogen atom, an alkylthio, aralkylthio, alkylthioxo or aralkylthioxo radical, or a NR4R5 radical wherein R4 represents an alkyl radical, a hydroxyalkyl radical, a cycloalkyl radical optionally substituted, an aralkyl radical whereof the aryl radical is optionally substituted, or R4 represents a heteroaryl or heteroarylalkyl radical, the heteroaryl radical of the heteroaryl or hete
    Type: Application
    Filed: June 6, 2003
    Publication date: March 11, 2004
    Inventors: Gregoire Prevost, Marie-Odile Lonchampt, Sun Kim, Barru Morgan, Gerard Ulibarri, Christophe Thurieau
  • Amidine derivatives, their preparation and application as medicines and pharmaceutical compositions containing same
    Patent number: 6653312
    Abstract: Amidine compounds of the formula wherein the substituents are defined as in the application useful as NO-synthase enzyme inhibitors.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: November 25, 2003
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Serge Auvin, Pierre-Etienne Chabrier de Lassauniere, Jeremiah Harnett, Dominique Pons, Gérard Ulibarri
  • Tetracyclic analogues of camptothecins, their preparation processes, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6632946
    Abstract: The invention relates to new tetracyclic analogues of camptothecin, their preparation processes, their use as medicaments and the pharmaceutical compositions containing them. Said analogues, which include in particular 3-hydroxy-3-(4-oxo-4,6-dihydroindolizino[1,2-b]quinoline-2-yl)pentanoic acid, have a powerful biological activity inhibiting topoisomerase I and/or topoisomerase II.
    Type: Grant
    Filed: December 12, 2000
    Date of Patent: October 14, 2003
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Alain Rolland, Christophe Lanco, Gerard Ulibarri