Patents by Inventor Gerard Wagemaker

Gerard Wagemaker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6384194
    Abstract: Methods are provided for improved production of hIL-3 either in glycosylated form from mammalian and yeast cells or in unglycosylated form from prokaryotes. Recombinantly produced human IL-3 is purified in a series of steps, initially employing hydrophobic interaction, followed by ion exchange chromatography and gel filtration.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: May 7, 2002
    Assignee: DSM N.V.
    Inventors: Lambertus Christiaan Johannes Dorssers, Gerard Wagemaker, Yvonne Johanna Vos, Robert William Van Leen, Maria Ludovicus Nicolaas Persoon
  • Patent number: 6238889
    Abstract: The invention relates to nucleotide sequences encoding human interleukin-3 (hIL-3) as well as recombinant DNAs, expression cassettes, transformed host cells, and recombinant expression methods comprising such sequences. Additionally, the invention describes proteins having hIL-3 activity, as purified, recombinantly produced, or fusion protein forms of hIL-3, as well as methods of using such proteins to produce antibodies capable of immunospecific reaction with hIL-3.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 29, 2001
    Assignee: DSM N.V.
    Inventors: Lambertus Christian Johannes Dorssers, Gerard Wagemaker, Yvonne Johanna Vos, Robert Willem Van Leen
  • Patent number: 5304637
    Abstract: Methods are provided for improved production of hIL-3 either in glycosylated form from mammalian and yeast cells or in unglycosylated form from prokaryotes. Recombinantly produced human IL-3 is purified in a series of steps, initially employing hydrophobic interaction, followed by ion exchange chromatography and gel filtration.
    Type: Grant
    Filed: March 13, 1990
    Date of Patent: April 19, 1994
    Assignee: Gist-brocades N.V.
    Inventors: Lambertus C. J. Dorssers, Gerard Wagemaker, Yvonne J. Vos, Robert W. Van Leen, Maria L. N. Persoon