Patents by Inventor Gerard Wolff

Gerard Wolff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5391770
    Abstract: Process for preparing pure ascorbic acid from 2-keto-L-gulonic acid or its sodium salt, by carrying out the following successive steps:esterification of 2-keto-L-gulonic acid or its sodium saltlactonization to sodium ascorbateoptional separation of the sodium ascorbatedisplacement of the ascorbic acid from its saltseparation of the sodium sulphateseparation and purification of the ascorbic acid from its methanolic or aqueous-methanolic solution.
    Type: Grant
    Filed: December 23, 1993
    Date of Patent: February 21, 1995
    Assignee: Rhone Poulenc Rorer S.A.
    Inventors: Isidore Le Fur, Jean-Paul Richard, Gerard Wolff
  • Patent number: 4849417
    Abstract: The hydrated complex of magnesium acetylsalicylate and urea of formula ##STR1## possesses exceptional analgesic and antipyretic properties. It may be crystallized from a solution obtained by reacting acetylsalicylic acid with magnesium carbonate in the presence of urea.
    Type: Grant
    Filed: February 11, 1988
    Date of Patent: July 18, 1989
    Assignee: Rhone-Poulenc Sante
    Inventors: Claude Bertrand, Gerard Wolff
  • Patent number: 4764637
    Abstract: The hydrated complex of magnesium acetylsalicylate and urea of formula ##STR1## possesses exceptional analgesic and antipyretic properties. It may be crystallized from a solution obtained by reacting acetylsalicylic acid with magnesium carbonate in the presence of urea.
    Type: Grant
    Filed: April 18, 1986
    Date of Patent: August 16, 1988
    Assignee: Rhone-Poulenc Sante
    Inventors: Claude Bertrand, Gerard Wolff
  • Patent number: 4520193
    Abstract: The invention provides new cephalosporin derivatives of the general formula, ##STR1## which are in the form of a bicyclooct-2-ene or bicyclooct-3-ene, in which formula R.sub.1 is a radical of the general formula ##STR2## [in which R.sub.5 is hydrogen, alkyl, vinyl, cyanomethyl, protected carboxyalkyl or a protective radical and R.sub.6 is a protective radical] or an amino-protecting radical, R.sub.2 is an acid-protecting radical and R.degree. represents various organic radicals, or alternatively R.sub.1 is an amino-protecting radical or various acyl radicals, R.sub.2 is a protective radical and R.degree. represents various organic radicals, and R.sub.3 and R.sub.4 are alkyl radicals optionally substituted by alkoxy or dialkylamino, or phenyl radicals, or --NR.sub.3 R.sub.4 forms a heterocyclic ring. These products are intermediates for the synthesis of cephalosporins having antibacterial activity.
    Type: Grant
    Filed: November 19, 1981
    Date of Patent: May 28, 1985
    Assignee: Rhone-Poulenc Industries
    Inventors: Christian Berger, Daniel Farge, Claude Moutonnier, Gerard Wolff
  • Patent number: 4291032
    Abstract: New thiazolo[3,2-c]-1,3-benzoxazine derivatives of the general formula (I), in which X is oxygen or sulfur, R.sub.1 and R.sub.2, which are identical or different, are hydrogen or halogen atoms or alkyl, alkoxy, alkylthio or trifluoromethyl radicals, in the 7-, 8-, 9- or 10-position, and R.sub.3 is a hydrogen atom or a carboxyl radical, their salts, if appropriate, their preparation and the medicaments in which they are present.These new derivatives are particularly useful as analgesic agents.
    Type: Grant
    Filed: October 2, 1980
    Date of Patent: September 22, 1981
    Assignee: Rhone Poulenc Industries
    Inventors: Christian Berger, Daniel Farge, Claude Moutonnier, Gerard Wolff
  • Patent number: 4178290
    Abstract: .alpha.-Amino(1,3-dithiin-5-yl)-acetic acid in the D-, L-, or D,L-form and in which the amino radical is free or protected by tert.-butoxycarbonyl or 2,2,2-trichloroethoxycarbonyl is a useful intermediate in the preparation of cephalosporins having valuable antibacterial activity.
    Type: Grant
    Filed: June 6, 1978
    Date of Patent: December 11, 1979
    Assignee: Rhone-Poulenc Industries
    Inventors: Christian Berger, Dominique Deprez, Daniel Farge, Claude Moutonnier, Gerard Wolff