Abstract: A transgenic non-human mammal containing a heterologous lambda light chain gene locus, and/or a heterologous kappa light chain gene locus, and/or a heterologous heavy chain gene locus, each of which can re-arrange so that immunoglobulin heavy and light chain genes are formed and expressed in B-cells following antigen challenge.

Abstract: The invention relates to a poultry transfer mechanism for transferring poultry bodies from a first poultry transport line to a second poultry transport line. Further, the invention relates to a poultry transport system comprising a poultry transfer mechanism, a first poultry transport line and a second poultry transport line. In addition, the invention also relates to a method for automatically transferring at least one poultry body from a first poultry transport line to a second poultry transport line.

Abstract: An electro-static discharge (ESD) protection system for a wireless transceiver comprises a switch circuit at a first terminal and a second terminal of a low noise amplifier; a primary ESD protection circuit between an input terminal and a low voltage supply terminal of the wireless transceiver for shunting a first source of current of an ESD event; a clamp element between a high voltage supply terminal and the low voltage supply terminal having a clamping voltage that is less than a breakdown voltage of the LNA for preventing a second source of current of the ESD event from receipt by the LNA; and a power supply ESD clamp element between the high voltage supply terminal and the low voltage supply terminal for shunting a third source of current of the ESD event at the high voltage supply terminal.

Abstract: It is described an attenuation measurement device (100), comprising: i) a detector unit (110) having a coupling capacitance (120), and an input capacitance (130), wherein the detector unit (110) is configured to produce a detector output signal (112a,b) in reply to an input signal received at the coupling capacitance (120) and/or at the input capacitance (130); ii) a test unit (140), coupled to the detector unit (110), and configured to provide a test signal (141) with at least one known signal property as a first input signal to the coupling capacitance (120); iii) a calibration unit (150), coupled to the detector unit (110), and configured to provide a calibration signal (151) as a second input signal to the input capacitance (130); and iv) a control unit configured to a) determine a first detector output signal (112a) produced by the detector unit (110) in response to the test signal (141), b) identify a specific calibration signal (151) that yields a second detector output signal (112b) that is compa

Abstract: The present invention concerns novel and improved antibody-conjugates for targeting HER2. The inventors found that when antibody-conjugates were prepared using a specific mode of conjugation, they exhibit an improved therapeutic index.

Abstract: The present invention concerns novel and improved antibody-conjugates for targeting CD30. The inventors found that when antibody-conjugates were prepared using a specific mode of conjugation, they exhibit an improved therapeutic index.

Abstract: Aspects of the present disclosure are directed to injection locking and related apparatuses. As may be implemented in accordance with one or more embodiments, an apparatus includes a plurality of injection-locking circuits configured to receive an injection signal, each injection-locking circuit including a mixer and a lock-detection circuit. In each of the injection-locking circuits, the lock-detection circuit detects a lock-status relationship between the injection signal and a signal output from the injection-locking circuit. In response to the lock-status relationship indicating an unlocked condition, a phase/magnitude of the injection signal is adjusted. In response to the lock-status relationship indicating a locked condition, transmission of an FM continuous wave (FMCW) chirp signal is facilitated.

Abstract: The invention relates to a poultry transfer mechanism for transferring poultry bodies from a first poultry transport line to a second poultry transport line. Further, the invention relates to a poultry transport system comprising a poultry transfer mechanism, a first poultry transport line and a second poultry transport line. In addition, the invention also relates to a method for automatically transferring at least one poultry body from a first poultry transport line to a second poultry transport line.

Abstract: The present invention concerns novel and improved antibody-conjugates for targeting HER2. The inventors found N that when antibody-conjugates were prepared using a specific mode of conjugation, they exhibit an improved therapeutic index.

Abstract: Aspects of the present disclosure are directed to injection locking and related apparatuses. As may be implemented in accordance with one or more embodiments, an apparatus includes a plurality of injection-locking circuits configured to receive an injection signal, each injection-locking circuit including a mixer and a lock-detection circuit. In each of the injection-locking circuits, the lock-detection circuit detects a lock-status relationship between the injection signal and a signal output from the injection-locking circuit. In response to the lock-status relationship indicating an unlocked condition, a phase/magnitude of the injection signal is adjusted. In response to the lock-status relationship indicating a locked condition, transmission of an FM continuous wave (FMCW) chirp signal is facilitated.

Abstract: The present invention concerns novel and improved antibody-conjugates for targeting HER2. The inventors found N that when antibody-conjugates were prepared using a specific mode of conjugation, they exhibit an improved therapeutic index.

Abstract: The present invention concerns novel and improved antibody-conjugates for targeting CD30. The inventors found that when antibody-conjugates were prepared using a specific mode of conjugation, they exhibit an improved therapeutic index.

Abstract: A vibration isolator is provided including a base structure, a load structure, a displacement structure and at least one vertical open gap formed by opposing and substantially parallel walls of the base structure and the load structure. The opposing walls being at least partly covered by respective arrays of permanent magnets, neighboring magnets in the arrays having alternating magnetization directions, an arrangement of the permanent magnets in the arrays being such that a gravitational force on the load structure is substantially compensated by a net magnetic force of the base structure on the load structure. The displacement structure relatively displaces arrays of permanent magnets of the opposing walls with respect to each along the gap for adjusting a load capacity of the vibration isolator.

Abstract: A vibration isolator is provided comprising a base structure, a load structure, a displacement structure and at least one vertical air gap formed by opposing and substantially parallel walls of the base structure and the load structure. The opposing walls being at least partly covered by respective arrays of permanent magnets, neighboring magnets in the arrays having alternating magnetization directions, an arrangement of the permanent magnets in the arrays being such that a gravitational force on the load structure is substantially compensated by a net magnetic force of the base structure on the load structure. The displacement structure relatively displaces arrays of permanent magnets of the opposing walls with respect to each along the air gap for adjusting a load capacity of the vibration isolator.

Abstract: A vibration isolator is provided comprising a base structure, a load structure and at least one vertical air gap formed by opposing and substantially parallel walls of the base structure and the load structure. The opposing walls being at least partly covered by respective arrays of permanent magnets, neighboring magnets in the arrays having alternating magnetization directions, an arrangement of the permanent magnets in the arrays being such that a gravitational force on the load structure is substantially compensated by a net magnetic force of the base structure on the load structure.

Abstract: A vibration isolator is provided comprising a base structure, a load structure and at least one vertical air gap formed by opposing and substantially parallel walls of the base structure and the load structure. The opposing walls being at least partly covered by respective arrays of permanent magnets, neighboring magnets in the arrays having alternating magnetization directions, an arrangement of the permanent magnets in the arrays being such that a gravitational force on the load structure is substantially compensated by a net magnetic force of the base structure on the load structure.

Abstract: Method for determining the location and/or speed of at least one swimmer, swimming through water, comprising: —sending acoustic signals through the water, using stationary acoustic transmitter means (AT) having a stationary position, or using mobile acoustic transmitter means (AT?) being carried by said swimmer (S); —receiving the acoustic signals using mobile acoustic receiver means (AR) being carried by said swimmer (S), or using stationary acoustic receiver means (AR?) respectively; —determining the time difference between the time of sending and the time of receiving each acoustic signal; —determining a location and/or speed of said swimmer (S) with respect to said stationary transmitter means (AT) or stationary receiver means (AR?), using said time differences and a predetermined propagation speed of the acoustic signal through the water.

Abstract: Oil compositions containing Hoodia plant extract dissolved in medium chain tri-acyl-glycerides. Edible emulsions comprising the inventive oil compositions are also disclosed.

Abstract: The present invention provides assays and kits for the screening of test compounds for their capability to induce cardiotoxicity in a subject. Said assays and kits are based on the finding that the interaction of astemizole with the HERG potassium channel can be exploited to predict cardiotoxicity of compounds during the development of new therapeutics and other agents.

Abstract: The invention provides a method for converting a hydrocarbon feedstock to propylene comprising: contacting an olefinic hydrocarbon feedstock boiling in the naphtha range with a catalyst comprising a zeolitic catalyst selected from the group consisting of medium pore zeolites having a ratio of silica to alumina above 200 and pore diameter less than 0.7 nm under cracking conditions to selectively produce propylene. The preferred catalyst comprises of a zeolite having an 8, 10, or 12 membered ring pore structure. The preferred catalysts are selected from the group consisting of zeolites from the families MFI, MEL, MTW, TON, MTT, FER, MFS, and the zeolites ZSM-21, ZSM-38 and ZSM-48. Preferably the method is carried out to produce propylene with greater than 50% specificity, more preferably, the propylene to butylene ratio is at least 2:1 or a propylene to ethylene ratio of at least 4:1. The olefinic hydrocarbon feedstock consists essentially of hydrocarbons boiling within the range of 18° to 220° C.