Patents by Inventor Gerardus Kemperman

Gerardus Kemperman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition comprising a salt of mirtazapine
    Publication number: 20070111993
    Abstract: The invention provides for a pharmaceutically suitable non-sublimating and solid salt of an enantiomer of mirtazapine, in particular, a mirtazapine salt selected from the list of the salt of maleic acid, hydrobromic acid and fumaric acid, for use in the manufacture of a pharmaceutical composition comprising a salt of S- or R-mirtazapine.
    Type: Application
    Filed: April 19, 2005
    Publication date: May 17, 2007
    Applicant: AKZO NOBEL N.V.
    Inventors: Sytske Moolenaar, Gerardus Kemperman, Kees Van Der Voort Maarschalk
  • Method for the preparation of enantiomerically pure mirtazapine
    Publication number: 20060229300
    Abstract: The invention provides a method for the preparation of enantiomerically pure mirtazapine, said method comprising a step of ring closure of a compound of formula (II) wherein X is a leaving group, said step comprising treatment with an acid, whereby mirlazapine with enantiomeric excess is formed by the ring closure of the compound of formula (II) with enantiomeric excess by treatment with a suitable acid in the absence of a solvent or a suitable combination of an acid and an organic solvent.
    Type: Application
    Filed: July 5, 2004
    Publication date: October 12, 2006
    Applicant: AKZO NOBEL N.V.
    Inventors: Johannes Wieringa, Adrianus Antonius Van De Ven, Gerardus Kemperman
  • Intermediate compounds for the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole
    Publication number: 20060229352
    Abstract: Disclosed are novel amino acid derivatives of formula (I) and (II) processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.
    Type: Application
    Filed: April 6, 2006
    Publication date: October 12, 2006
    Applicants: Organon Ireland Ltd., Pfizer Inc.
    Inventors: Gerardus Kemperman, Jacobus Van Der Linden, Michael Reeder