Patents by Inventor Gerben Van Eldik

Gerben Van Eldik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11060103
    Abstract: The present invention relates to novel gene sequences encoding insecticidal proteins produced by Bacillus thuringiensis strains. Particularly, new chimeric genes encoding a CryIC, CryIB or CryID protein are provided which are useful to protect plants from insect damage. Also included herein are plant cells or plants comprising such genes and methods of making or using them, as well as plant cells or plants comprising one of such chimeric gene and at least one other such chimeric genes.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: July 13, 2021
    Assignee: BASF AGRICULTURAL SOLUTIONS SEED, US LLC
    Inventors: Jeroen Van Rie, Frank Meulewaeter, Gerben Van Eldik
  • Patent number: 10196664
    Abstract: The invention provides methods for reducing the levels of alfa (1,3)-fucosylated N-glycans on glycoproteins produced in plants or plant cells. In addition, the invention provides alfa(1,3)-fucosyltransferase genes from Nicotiana benthamiana, and mutant N. benthamiana plants in which the levels of alfa(1,3)-fucosylated N-glycans are reduced.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: February 5, 2019
    Assignee: Icon Genetics GmbH
    Inventors: Koen Weterings, Gerben Van Eldik
  • Publication number: 20170107534
    Abstract: The present invention relates to novel gene sequences encoding insecticidal proteins produced by Bacillus thuringiensis strains. Particularly, new chimeric genes encoding a CryIC, CryIB or CryID protein are provided which are useful to protect plants from insect damage. Also included herein are plant cells or plants comprising such genes and methods of making or using them, as well as plant cells or plants comprising one of such chimeric gene and at least one other such chimeric genes.
    Type: Application
    Filed: December 29, 2016
    Publication date: April 20, 2017
    Inventors: Jeroen VAN RIE, Frank Meulewaeter, Gerben Van Eldik
  • Publication number: 20150080553
    Abstract: The invention provides methods for reducing the levels of alfa (1,3)-fucosylated N-glycans on glycoproteins produced in plants or plant cells. In addition, the invention provides alfa(1,3)-fucosyltransferase genes from Nicotiana benthamiana, and mutant N. benthamiana plants in which the levels of alfa(1,3)-fucosylated N-glycans are reduced.
    Type: Application
    Filed: October 4, 2012
    Publication date: March 19, 2015
    Inventors: Koen Weterings, Gerben Van Eldik
  • Patent number: 8933297
    Abstract: The invention provides Nicotiana benthamiana mutant plants which are incapable of forming xylosyl-structures on glycoproteins. In addition, the invention provides methods for the production of heterologous glycoproteins in said mutant plants.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: January 13, 2015
    Assignee: Icon Genetics GmbH
    Inventors: Koen Weterings, Gerben Van Eldik
  • Publication number: 20120083014
    Abstract: The invention provides Nicotiana benthamiana mutant plants which are incapable of forming xylosyl-structures on glycoproteins. In addition, the invention provides methods for the production of heterologous glycoproteins in said mutant plants.
    Type: Application
    Filed: June 10, 2010
    Publication date: April 5, 2012
    Inventors: Koen Weterings, Gerben Van Eldik
  • Publication number: 20100242128
    Abstract: Provided is a novel method to produce a plant cell or plant having an altered N-glycosylation pattern resulting, in particular, in a low level of ?-1,2-xylose residues and core ?-1,3-fucose residues on protein-bound N-glycans. The plant cell or plant is of particular interest for producing therapeutic glycoproteins with a low, or not detectable, level of ?-1,2-xylose and ?-1,3-fucose residues. Also provided are novel ?-1,3-fucosyltransferase nucleotide sequences and uses.
    Type: Application
    Filed: October 31, 2007
    Publication date: September 23, 2010
    Applicant: Bayer BioSceince NV
    Inventors: Herta Steinkellner, Richard Strasser, Josef Glössl, Koen Weterings, Gerben Van Eldik
  • Publication number: 20100235951
    Abstract: The present invention relates to novel gene sequences encoding insecticidal proteins produced by Bacillus thuringiensis strains. Particularly, new chimeric genes encoding a Cry1C, Cry1B or Cry1D protein are provided which are useful to protect plants from insect damage. Also included herein are plant cells or plants comprising such genes and methods of making or using them, as well as plant cells or plants comprising one of such chimeric gene and at least one other of such chimeric genes.
    Type: Application
    Filed: March 16, 2007
    Publication date: September 16, 2010
    Applicant: Bayer BioScience N.V.
    Inventors: Jeroen Van Rie, Frank Meulewaeter, Gerben Van Eldik
  • Publication number: 20100154081
    Abstract: The invention provides methods to modify the N-glycosylation pattern of glycoproteins in higher plant cells, through reducing or eliminating the level of ?(1,2) xylosyltransferase and ? (1,3) fucosyltransferase activity and increasing the ?(1,4) galactosyltransferase activity in the cell of the higher plant.
    Type: Application
    Filed: May 20, 2008
    Publication date: June 17, 2010
    Applicant: BAYER BIOSCIENCE N.V.
    Inventors: Koen Weterings, Gerben Van Eldik, Bicke Nagels
  • Patent number: 7554005
    Abstract: The invention relates to the isolation of promoters from corn capable of directing transcription of an operably linked foreign DNA sequence preferentially, selectively or exclusively in the roots of plants, such as corn plants. The invention also relates to the use of chimeric genes for the preferential or selective expression of biologically active RNA of interest in the roots of plants, such as corn plants. Plants, such as corn plants, comprising corn root preferential or selective promoters operably linked to a foreign DNA sequence which, upon transcription, yield biologically active RNA preferentially or selectively in the roots of plants are also provided.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: June 30, 2009
    Assignee: Bayer Bioscience N.V.
    Inventors: Greet Vanderkimpen, Gerben Van Eldik, Frank Meulewaeter
  • Publication number: 20070174938
    Abstract: The invention relates to the isolation of promoters from corn capable of directing transcription of an operably linked foreign DNA sequence preferentially, selectively or exclusively in the roots of plants, such as corn plants. The invention also relates to the use of chimeric genes for the preferential or selective expression of biologically active RNA of interest in the roots of plants, such as corn plants. Plants, such as corn plants, comprising corn root preferential or selective promoters operably linked to a foreign DNA sequence which, upon transcription, yield biologically active RNA preferentially or selectively in the roots of plants are also provided.
    Type: Application
    Filed: March 8, 2007
    Publication date: July 26, 2007
    Applicant: Bayer BioScience N.V.
    Inventors: Greet Vanderkimpen, Gerben Van Eldik, Frank Meulewaeter
  • Patent number: 7205454
    Abstract: The invention relates to the isolation of promoters from corn capable of directing transcription of an operably linked foreign DNA sequence preferentially, selectively or exclusively in the roots of plants, such as corn plants. The invention also relates to the use of chimeric genes for the preferential or selective expression of biologically active RNA of interest in the roots of plants, such as corn plants. Plants, such as corn plants, comprising corn root preferential or selective promoters operably linked to a foreign DNA sequence which, upon transcription, yield biologically active RNA preferentially or selectively in the roots of plants are also provided.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: April 17, 2007
    Assignee: Bayer BioScience N.V.
    Inventors: Greet Vanderkimpen, Gerben Van Eldik, Frank Meulewaeter
  • Patent number: 7148400
    Abstract: The invention provides methods and means for the identification of genes involved in the determination of a plant trait or for the identification encoded by a nucleic acid comprising a determined nucleotide sequence. The invention also provides kits comprising viral RNA vectors derived from satellite viruses and corresponding helper viruses for the introduction of inhibitory RNA into plant cells and plants.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: December 12, 2006
    Assignee: Bayer BioScience N.V.
    Inventors: Frank Meulewaeter, Marc Cornelissen, John Jacobs, Gerben Van Eldik, Michael Metzlaff
  • Publication number: 20040133945
    Abstract: The invention relates to the isolation of promoters from corn capable of directing transcription of an operably linked foreign DNA sequence preferentially, selectively or exclusively in the roots of plants, such as corn plants. The invention also relates to the use of chimeric genes for the preferential or selective expression of biologically active RNA of interest in the roots of plants, such as corn plants. Plants, such as corn plants, comprising corn root preferential or selective promoters operably linked to a foreign DNA sequence which, upon transcription, yield biologically active RNA preferentially or selectively in the roots of plants are also provided.
    Type: Application
    Filed: July 22, 2003
    Publication date: July 8, 2004
    Applicant: Bayer BioScience N.V.
    Inventors: Greet Vanderkimpen, Gerben Van Eldik, Frank Meulewaeter