Abstract: The present invention relates to Map4K1 inhibitors of formula (I) (I), wherein A, E, G, Q, R1, R2 and R4 have the same meaning as defined in the description, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.

Abstract: The invention relates to L-shaped sheet metal parts 21 with an angled longitudinal recess 23 as well as a reinforced concrete/prestressed concrete component with at least one upper and at least one lower longitudinal reinforcement layer and a shear force reinforcement guided in its dimension over the uppermost and the lowermost longitudinal reinforcement, which is formed from the L-shaped sheet metal parts 21 according to the invention with stirrups 30 fastened in the longitudinal recess 23. The reinforced concrete/prestressed concrete component according to the invention is suitable for increasing the punching shear resistance in the region of slab columns of flat slabs.

Abstract: The invention relates to L-shaped sheet metal parts 21 with an angled longitudinal recess 23 as well as a reinforced concrete/prestressed concrete component with at least one upper and at least one lower longitudinal reinforcement layer and a shear force reinforcement guided in its dimension over the upper-most and the lowermost longitudinal reinforcement, which is formed from the L-shaped sheet metal parts 21 according to the invention with stirrups 30 fastened in the longitudinal recess 23. The reinforced concrete/prestressed concrete component according to the invention is suitable for increasing the punching shear resistance in the region of slab columns of flat slabs.

Abstract: Reinforced concrete component with at least one upper and at least one lower longitudinal reinforcement layer, and one transverse force reinforcement. Transverse force reinforcement being passed to the upper and lower longitudinal reinforcement in its extension. The transverse force reinforcement is formed by at least 20 L-shaped sheet metal components made from structural steel with stirrups attached thereto. Each sheet metal component thereby comprises a chamfer.

Abstract: A reinforced concrete component with at least one upper and at least one lower longitudinal reinforcement layer, and one transverse force reinforcement, wherein the latter is passed above an uppermost and a lowermost longitudinal reinforcement in its extension. The transverse force reinforcement is formed by at least 20 trapezoidal or triangular sheet metal components made from structural steel. Each sheet metal component has at its two ends one splay/chamfer. The chamfer is passed to the uppermost or lowermost longitudinal reinforcement, respectively.

Abstract: Reinforced concrete component with at least one upper and at least one lower longitudinal reinforcement layer, and one transverse force reinforcement. Transverse force reinforcement being passed to the upper and lower longitudinal reinforcement in its extension. The transverse force reinforcement is formed by at least 20 L-shaped sheet metal components made from structural steel with stirrups attached thereto. Each sheet metal component thereby comprises a chamfer.

Abstract: A reinforced concrete component with at least one upper and at least one lower longitudinal reinforcement layer, and one transverse force reinforcement, wherein the latter is passed above an uppermost and a lowermost longitudinal reinforcement in its extension. The transverse force reinforcement is formed by at least 20 trapezoidal or triangular sheet metal components made from structural steel. Each sheet metal component has at its two ends one splay/chamfer. The chamfer is passed to the uppermost or lowermost longitudinal reinforcement, respectively.

Abstract: The innovation concerns components and their application in concrete components, in particular in shear stressed reinforced concrete components. Proposed are novel concrete components which, apart from the flexural reinforcement, also intend different types of shear reinforcements in the form of novel components which at least partially encircle the flexural reinforcement.