Patents by Inventor Gerd Kruger
Gerd Kruger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9585913Abstract: The invention relates to a clay mineral for use as an agent for reducing the concentration of inorganic phosphate in liquids, in particular in bodily fluids or dialysis liquids, in order to treat hyperphosphatemia, in particular in a renal replacement therapy, wherein before use, the clay mineral is thermally treated at a temperature between 400° C. and 800° C., preferably between 500° C. and 700° C., in particular preferably at 550° C., over a time period of 60 min to 240 min, preferably 90 min to 180 min, in particular preferably 120 min.Type: GrantFiled: May 31, 2013Date of Patent: March 7, 2017Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Furschung e.V.Inventors: Steffen Mitzner, Claus Kerkhoff, Frank Emmrich, Anne Breitruck, Peggy Bodammer, Gerd Kruger, Rainer Dallwig
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Patent number: 9527631Abstract: The invention relates to a stopper (1) for a beverage container, a tapping assembly and a beverage container (100). The stopper (1) comprises an outer part (4) which has a ring flange (41) and a sleeve (42), the sleeve (42), below the ring flange (41), being circumferentially deformed to form a bulge (43), and a spreading ring (3) which has a ring flange (31) and a plurality of L-shaped elements (32) which have a pivot (D) at the angle of the “L” and the free ends of which are designed as hooks (33), and a bushing (2) and a rotational cover (5), which has a cover plate (54) and a sleeve (51). When the stopper (1) is in a position of nonuse, the spreading ring (3) is pre-positioned in the outer part (4), the bushing (2) protrudes partially into the spreading ring (3), and the hooks (33) point radially inward.Type: GrantFiled: April 11, 2013Date of Patent: December 27, 2016Assignee: Fass-Frisch GmbHInventors: Dennis Grittmann, Michael Diefenbacher, Gerd Krüger
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Publication number: 20150258138Abstract: The invention relates to a clay mineral for use as an agent for reducing the concentration of inorganic phosphate in liquids, in particular in bodily fluids or dialysis liquids, in order to treat hyperphosphatemia, in particular in a renal replacement therapy, wherein before use, the clay mineral is thermally treated at a temperature between 400° C. and 800° C., preferably between 500° C. and 700° C., in particular preferably at 550° C., over a time period of 60 min to 240 min, preferably 90 min to 180 min, in particular preferably 120 min.Type: ApplicationFiled: May 31, 2013Publication date: September 17, 2015Applicant: FIM BIOTECH GmbHInventors: Steffen Mitzner, Claus Kerkhoff, Frank Emmrich, Anne Breitruck, Peggy Bodammer, Gerd Kruger, Rainer Dallwig
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Publication number: 20150108080Abstract: The invention relates to a stopper (1) for a beverage container, a tapping assembly and a beverage container (100). The stopper (1) comprises an outer part (4) which has a ring flange (41) and a sleeve (42), the sleeve (42), below the ring flange (41), being circumferentially deformed to form a bulge (43), and a spreading ring (3) which has a ring flange (31) and a plurality of L-shaped elements (32) which have a pivot (D) at the angle of the “L” and the free ends of which are designed as hooks (33), and a bushing (2) and a rotational cover (5), which has a cover plate (54) and a sleeve (51). When the stopper (1) is in a position of nonuse, the spreading ring (3) is pre-positioned in the outer part (4), the bushing (2) protrudes partially into the spreading ring (3), and the hooks (33) point radially inward.Type: ApplicationFiled: April 11, 2013Publication date: April 23, 2015Applicant: Fass-Frisch GmbHInventors: Dennis Grittmann, Michael Diefenbacher, Gerd Krüger
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Patent number: 6712872Abstract: The invention relates to a valve body produced by powder metallurgical methods that exhibits high thermal and wear resistance and has the following composition by weight: 0.5% to 2.0% C; 5.0% to 16% Mo; 0.2% to 1.0% P; 0.1% to 1.4% Mn; 0% to 5% Cr; 0% to 5% S; 0% to 7% W; 0% to 3% V, <2% of other elements with the remainder being Fe. It also relates to a valve fitted with such valve body.Type: GrantFiled: November 12, 2002Date of Patent: March 30, 2004Assignees: Bleistahl-Produktions GmbH, Volkswagen AktiengesellschaftInventors: Gerd Krüger, Hans-Joachim Kaschuba, Franz-Josef Schleifstein
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Publication number: 20030136475Abstract: The invention relates to a valve body produced by powder metallurgical methods that exhibits high thermal and wear resistance and has the following composition by weight:Type: ApplicationFiled: November 12, 2002Publication date: July 24, 2003Inventors: Gerd Kruger, Hans-Joachim Kaschuba, Franz-Josef Schleifstein
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Patent number: 6112803Abstract: The cylinder head for internal combustion engines is produced by pouring liquid cylinder head material, especially aluminum, into a cylinder head mold containing a mold core having stepped sections in the region of the valve seat ring and the valve guide. The valve seat rings and valve guides are produced from a conventional material based on steel or copper by pressing and sintering in such a way that they have an open pore volume of 5 to 15%, a valve seat and/or a valve guide are laid on the stepped sections of the mold core, whereafter liquid aluminum is poured into the preheated mold and the mold core is removed in the conventional way after the molten aluminum has solidified.Type: GrantFiled: September 28, 1998Date of Patent: September 5, 2000Assignee: Bleistahl Produktions-GmbH & Co. KGInventor: Gerd Kruger
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Patent number: 5735043Abstract: In a method for mounting and finishing a valve seat ring in an operational position of a receiving bore at the entrance of a gas channel of the cylinder head of an internal combustion engine consisting of a light alloy, an annular body with a central opening is manufactured by powder pressing and sintering. A roller burnishing tool is positioned within the central of the annular body. The annular body is inserted into the receiving bore with the aid of the roller burnishing tool such that the annular body is positioned with play relative the inner wall of the receiving bore. The annular body is radially expanded by roller burnishing with the roller burnishing tool such that the annular body positive-lockingly engages the inner wall of the receiving bore and is compressed to a selected finish size of ready-to-use density.Type: GrantFiled: March 28, 1996Date of Patent: April 7, 1998Assignee: Bleistahl Produktions- GmbH & Co. KGInventors: Holger Schmidt, Gerd Kruger
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Patent number: 5187977Abstract: An apparatus for the recognition of a rising slope is provided in particular for commercial vehicles, such as trucks or busses. The device comprises at least one sensor (1) for the axle load of the rear axle and/or of the front axle, as well as a device (4) for measuring the vehicle acceleration relative to the road. The signals of the sensor (1) and of the device (4) are fed into an electronics (2). The electronics (2) recognizes from these fed-in data, whether the vehicle is disposed on an uphill grade or on a downhill grade or on level ground. The thus generated signal can be further employed in various electronic systems, for example, in an automatic drawbar force control system.Type: GrantFiled: March 28, 1991Date of Patent: February 23, 1993Assignee: WABCO Westinghouse Fahrzeugbremsen GmbHInventors: Ralf Koschorek, Gerd Kruger, Hartmut Rosendahl, Johann Rothen
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Patent number: 5084449Abstract: Disclosed are substituted bis(4-aminophenyl-sulfonees of general formula ##STR1## wherein R.sub.1 is hydrogen, alkyl or cycloalkyl; group,R.sub.2 is hydrogen or C.sub.1 -C.sub.3 alkyl,R.sub.3 is nitrile, C.sub.1 -C.sub.3 alkylaminocarbonyl, di C.sub.1 -C.sub.3 alkylaminocarbonyl, C.sub.3 -C.sub.7 N-cycloalkyl-C.sub.1 -C.sub.3 alkylaminocarbonyl C.sub.1 -C.sub.3 alkylamino, C.sub.1 -C.sub.3, di alkylaminocarbonyl alkoxy, alkylaminosulfonyl, di C.sub.1 -C.sub.3 alkylaminono, diC.sub.1 -C.sub.3 alkylaminosulfonyl, hydroxy C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkylcarbonyl, amino C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkoxy C.sub.1 -C.sub.3 alkyl groupor, when R.sub.1 and R.sub.2 are each hydrogen, R.sub.3 can be hydroxy, hydroxycarbonyl C.sub.1 -C.sub.3 alkoxy or di C.sub.1 -C.sub.3 aminocarbonylalkoxy;or, when R.sub.1 is C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 cycloalkyl and R.sub.2 is hydrogen or C.sub.1 -C.sub.3 alkyl, R.sub.Type: GrantFiled: December 7, 1990Date of Patent: January 28, 1992Assignee: Dr. Karl Thomae GmbHInventors: Joachim K. Seydel, Helmut Pieper, Gerd Kruger, Klaus Noll, Johannes Keck, Uwe Lechner
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Patent number: 4992430Abstract: Disclosed are substituted bis(4-aminophenyl)-sulfones of general formula ##STR1## wherein R.sub.1 is hydrogen, alkyl or cycloalkyl; group,R.sub.2 is hydrogen or C.sub.1 -C.sub.3 alkyl,R.sub.3 is nitrile, C.sub.1 -C.sub.3 alkylaminocarbonyl, di C.sub.1 -C.sub.3 alkylaminocarbonyl, C.sub.3 -C.sub.7 N-cycloalkyl-C.sub.1 -C.sub.3 alkylaminocarbonyl C.sub.1 -C.sub.3 alkylamino, C.sub.1 -C.sub.3, di alkylaminocarbonyl alkoxy, alkylaminosulfonyl, di C.sub.1 -C.sub.3 alkylaminono, diC.sub.1 -C.sub.3 alkylaminosulfonyl, hydroxy C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkylcarbonyl, amino C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkoxy C.sub.1 -C.sub.3 alkyl groupor, when R.sub.1 and R.sub.2 are each hydrogen, R.sub.3 can be hydroxy, hydroxycarbonyl C.sub.1 -C.sub.3 alkoxy or di C.sub.1 -C.sub.3 aminocarbonylalkoxy;or, when R.sub.1 is C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 cycloalkyl and R.sub.2 is hydrogen or C.sub.1 -C.sub.3 alkyl, R.sub.Type: GrantFiled: January 26, 1989Date of Patent: February 12, 1991Assignee: Dr. Karl Thomae GmbHInventors: Joachim K. Seydel, Helmut Pieper, Gerd Kruger, Klaus Noll, Johannes Keck, Uwe Lechner
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Patent number: 4829058Abstract: Disclosed are substituted bis(4-aminophenyl)-sulfones of general formula ##STR1## wherein R.sub.1 is hydrogen, alkyl or cycloalkyl; group,R.sub.2 is hydrogen or C.sub.1 -C.sub.3 alkyl,R.sub.3 is nitrile, C.sub.1 -C.sub.3 alkylaminocarbonyl, di C.sub.1 -C.sub.3 alkylaminocarbonyl, C.sub.3 -C.sub.7 N-cycloalkyl-C.sub.1 -C.sub.3 alkylaminocarbonyl C.sub.1 -C.sub.3 alkylamino, C.sub.1 -C.sub.3, di alkylaminocarbonyl alkoxy, alkylaminosulfonyl, di C.sub.1 -C.sub.3 alkylaminono, diC.sub.1 -C.sub.3 alkylaminosulfonyl, hydroxy C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkylcarbonyl, amino C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkoxy C.sub.1 -C.sub.3 alkyl groupor, when R.sub.1 and R.sub.2 are each hydrogen, R.sub.3 can be hydroxy, hydroxycarbonyl C.sub.1 -C.sub.3 alkoxy or di C.sub.1 -C.sub.3 aminocarbonylalkoxy;or, when R.sub.1 is C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 cycloalkyl and R.sub.2 is hydrogen or C.sub.1 -C.sub.3 alkyl, R.sub.Type: GrantFiled: June 15, 1987Date of Patent: May 9, 1989Assignee: Dr. Karl Thomae GmbHInventors: Joachim K. Seydel, Helmut Pieper, Gerd Kruger, Klaus Noll, Johannes Keck, Uwe Lechner
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Patent number: 4490369Abstract: Compounds of the formula ##STR1## wherein A is --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--, --NH--CO--, --CH.sub.2 --CO-- or ##STR2## where R.sub.7 is alkyl of 1 to 3 carbon atoms, andB is methylene, carbonyl or thiocarbonyl, orA is --CO--CO--, --N.dbd.CH--, ##STR3## where R.sub.8 is hydrogen or alkyl of 1 to 3 carbon atoms substituted by a phenyl, methoxyphenyl or dimethoxyphenyl, andB is methylene;E is n-alkylene of 2 to 4 carbon atoms optionally substituted by an alkyl of 1 to 3 carbon atoms, 2-hydroxy-n-propylene, 2-hydroxy-n-butylene or 3-hydroxy-n-butylene;G is n-alkylene of 1 to 5 carbon atoms optionally substituted by an alkyl of 1 to 3 carbon atoms, wherein one methylene group of an n-alkylene of 2 to 5 carbon atoms can be replaced by a carbonyl group, with the proviso that B represents a methylene or carbonyl group, or methylene-n-hydroxy-alkylene of 1 to 4 carbon atoms, where the methylene group is attached to the nitrogen atom; andR.sub.1 to R.sub.Type: GrantFiled: November 2, 1983Date of Patent: December 25, 1984Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter HaftungInventors: Manfred Reiffen, Joachim Heider, Norbert Hauel, Volkhard Austel, Wolfgang Eberlein, Walter Kobinger, Christian Lillie, Klaus Noll, Helmut Pieper, Gerd Kruger, Johannes Keck
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Patent number: 4362738Abstract: Compounds of the formula ##STR1## wherein each X, which may be identical or different from the other X, is oxygen or imino;R.sub.1 is hydrogen, fluorine, chlorine or bromine;R.sub.2 and R.sub.3, which may be identical or different from each other, are each hydrogen; unsubstituted or mono-substituted alkyl of 1 to 6 carbon atoms, where the substituent is phenyl or dialkylamino with 1 to 3 carbon atoms in each alkyl moiety; pyridyl; or cycloalkyl of 5 to 7 carbon atoms;R.sub.2 and R.sub.Type: GrantFiled: June 11, 1980Date of Patent: December 7, 1982Assignee: Dr. Karl Thomae GmbHInventors: Johannes Keck, Gerd Kruger, Helmut Pieper, Klaus Noll, Gunther Engelhardt, Norbert Promberger, Rainer Zimmermann
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Patent number: 4244967Abstract: The method of using compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, fluorine, chlorine, bromine, iodine or cyano,R.sub.2 is fluorine, cyano, trifluoromethyl, nitro or alkyl of 1 to 4 carbon atoms,R.sub.3 is cycloalkyl or alkyl, each of 3 to 5 carbon atoms, andR.sub.4 is hydrogen or --CO--R.sub.5, whereR.sub.5 is alkoxy of 1 to 5 carbon atoms, alkenyloxy of 2 to 5 carbon atoms, aryloxy of 6 to 10 carbon atoms, aralkoxy of 7 to 11 carbon atoms, or amino which may be mono- or di-substituted by alkyl of 1 to 5 carbon atoms, alkenyl of 2 to 5 carbon atoms, aryl of 6 to 10 carbon atoms and/or aralkyl of 7 to 11 carbon atoms,and non-toxic, pharmacologically acceptable acid addition salts thereof as antirheumatics and antiphlogistics.Type: GrantFiled: September 4, 1979Date of Patent: January 13, 1981Assignee: Boehringer Ingelheim GmbHInventors: Gunther Engelhardt, Johannes Keck, Gerd Kruger, Klaus Noll, Helmut Pieper, Rainer Zimmermann
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Patent number: 4119710Abstract: Racemic and optically active compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, fluorine, chlorine, bromine, iodine or cyano,R.sub.2 is fluorine, trifluoromethyl, nitro or cyano, andR.sub.3 is alkyl of 3 to 5 carbon atoms, hydroxy(alkyl of 3 to 5 carbon atoms), cycloalkyl of 3 to 5 carbon atoms, 1-(3,4-methylenedioxy-phenyl)-2-propyl or 1-(p-hydroxy-phenyl)-2-propyl,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as analgesics, uterospasmolytics, bronchospasmolytics and antispastics for the skeletal musculature, and especially as .beta..sub.2 -receptor mimetics and .beta..sub.1 -receptor blockers.Type: GrantFiled: December 28, 1976Date of Patent: October 10, 1978Assignee: Boehringer Ingelheim GmbHInventors: Gunther Engelhardt, Johannes Keck, Gerd Kruger, Klaus-Reinhold Noll, Helmut Pieper
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Patent number: 4113777Abstract: Compounds of the formula ##STR1## wherein X and R.sub.1 are each chlorine or bromine;R.sub.2 is isopropyl; tert.butyl; tert.pentyl; mono-, di- or tri-hydroxy-substituted branched alkyl of 3 to 5 carbon atoms; cyclohexyl; or hydroxycyclohexyl; andR.sub.3 is alkyl of 1 to 4 carbon atoms or, when R.sub.2 is other than cyclohexyl, also hydrogen;And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as secretolytics, antitussives, anti-ulcerogenics and stimulants for the production of the surfactant or antiatelectasis factor of the alveoli.Type: GrantFiled: July 1, 1977Date of Patent: September 12, 1978Assignee: Boehringer Ingelheim GmbHInventors: Johannes Keck, Sigfrid Puschmann, Gerd Kruger, Klaus-Reinhold Noll, Matyas Leitold, Helmut Pieper
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Patent number: 4101671Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or aliphatic or aromatic carboxylic acyl,R.sub.2 is hydrogen, chlorine or bromine,R.sub.3 is fluorine, alkyl of 1 to 4 carbon atoms, trifluoromethyl, cyano, carbamoyl, carboxyl, carbalkoxy, alkoxy, acetyl, 1-hydroxyethyl or ##STR2## where R.sub.6 and R.sub.7 are each alkyl, cycloalkyl, hydroxy-cycloalkyl or, together with each other and the nitrogen atom to which they are attached, pyrrolidino, piperidino or morpholino, andR.sub.4 and R.sub.5 are each hydrogen, alkyl of 1 to 5 carbon atoms, mono- or di-hydroxy (alkyl of 1 to 5 carbon atoms), alkenyl of 2 to 4 carbon atoms, cycloalkyl of 5 to 7 carbon atoms, mono- or di-hydroxy (cycloalkyl of 5 to 7 carbon atoms), benzyl, morpholinocarbonylmethyl or, together with each other and the nitrogen atom to which they are attached, pyrrolidino, piperidino, hexamethyleneimino, morpholino, N-methyl-piperazino or camphidino,Provided, however, that when R.sub.3 is carboxyl or carbalkoxy, R.sub.4 and R.sub.Type: GrantFiled: March 24, 1977Date of Patent: July 18, 1978Assignee: Boehringer Ingelheim GmbHInventors: Johannes Keck, Klaus-Reinhold Noll, Helmut Pieper, Gerd Kruger, Sigfrid Puschmann
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Patent number: 4093734Abstract: Compounds of the formula ##STR1## wherein (A) WHEN THE AMINO-SUBSTITUENT IS IN THE P-POSITION WITH RESPECT TO THE CARBONYL GROUP,R.sub.1 is chlorine in the o-position with respect to the carbonyl group,R.sub.2 is hydrogen, andR.sub.3 is ethylamino, cyclopentylamino, cyclohexylamino, cycloheptylamino, N-methyl-cyclohexylamino, benzylamino or 1-ethyl-pyrrolidyl-(2)-aminomethyl, or(b) when the amino-substituent is in the o--, m-- or p-position with respect to the carbonyl group,R.sub.1 is hydrogen, chlorine or bromine,R.sub.2 is trifluoromethyl, nitro or, when R.sub.4 is 1-(alkyl of 1 to 3 carbon atoms)-pyrrolidyl or 1-(alkyl of 1 to 3 carbon atoms)-piperidyl, also fluorine, chlorine, bromine or methyl,R.sub.3 is (alkyl of 1 to 5 carbon atoms)-amino, (cycloalkyl of 3 to 7 carbon atoms)-amino, benzylamino, quinuclidinyl-amino or --NH--(CH.sub.2).sub.n --R.sub.4where R.sub.Type: GrantFiled: October 22, 1976Date of Patent: June 6, 1978Assignee: Boehringer Ingelheim GmbHInventors: Gerd Kruger, Johannes Keck, Klaus Reinhold Noll, Helmut Pieper, Harald Ziegler, Helmut Ballhause, Joachim Kahling
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Patent number: RE29628Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or aliphatic or aromatic carboxylic acyl,R.sub.2 is hydrogen, chlorine or bromine,R.sub.3 is fluorine, alkyl of 1 to 4 carbon atoms, trifluoromethyl, cyano, carbamoyl, carboxyl, carbalkoxy, alkoxy, acetyl, 1-hydroxyethyl or ##STR2## where R.sub.6 and R.sub.7 are each alkyl, cycloalkyl, hydroxy-cycloalkyl or, together with each other and the nitrogen atom to which they are attached, pyrrolidino, piperidino or morpholino, andR.sub.4 and R.sub.Type: GrantFiled: December 2, 1976Date of Patent: May 9, 1978Assignee: Boehringer Ingelheim GmbHInventors: Johannes Keck, Klaus-Reinhold Noll, Helmut Pieper, Gerd Kruger, Sigfrid Puschmann