Patents by Inventor Gerd Lindner

Gerd Lindner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200255799
    Abstract: The present invention describes a method for producing de novo papillae comprising the steps of a) providing isolated dermal papilla fibroblasts (DPF) from at least one dermal papilla (DP) from at least one hair follicle, b) providing isolated connective tissue sheath fibroblasts (CTSF) from at least one hair follicle and c) co-culturing the DPF with the CTSF under substantially non-adherent cell culture conditions to form spheroid cell aggregates.
    Type: Application
    Filed: November 14, 2016
    Publication date: August 13, 2020
    Applicant: TECHNISCHE UNIVERSIT√ĄT BERLIN
    Inventor: Gerd LINDNER
  • Publication number: 20200255808
    Abstract: A method for producing a skin equivalent comprising the steps of: a) producing a dermal matrix containing a first layer and a second layer comprises the steps of i) providing the first layer; ii) providing a polymerizable solution comprising a liquid and at least one polymer; iii) adding the polymerizable solution to the first layer; iv) polymerizing the solution to form the second layer; v) compressing the second layer, wherein as a result of the compression the liquid content of the second layer is reduced and the first layer and second layer are joined together to form the dermal matrix; and vi) introducing at least one cavity into the dermal matrix; b) introducing at least one hair follicle and/or hair follicle germ into the at least one cavity of the dermal matrix produced in step a) to produce a skin surrogate; and c) adding at least one further cell population.
    Type: Application
    Filed: November 14, 2016
    Publication date: August 13, 2020
    Applicant: TECHNISCHE UNIVERSIT√ĄT BERLIN
    Inventor: Gerd LINDNER
  • Patent number: 9764064
    Abstract: The present invention relates to a method for producing hair microfollicles comprising the steps of: a) providing de novo papillae, b) providing other cell populations selected from the group of fibroblasts, keratinocytes and melanocytes, and co-culturing the de novo papillae with at least one other cell population in non-adherent culture vessels. The present invention relates also to methods of producing de novo papillae usable in said method for producing hair microfollicles.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: September 19, 2017
    Assignee: TECHNISCHE UNIVERSITAT BERLIN
    Inventors: Gerd Lindner, Roland Lauster
  • Patent number: 9506024
    Abstract: A self-contained circulation system, which supports the formation of capillaries in capillary growth sections and allows the formation of micro organoids and/or micro tissue sections for monitoring the effect of one or more test compounds and determining efficacy, side-effects, biosafety, metabolites, mode of action or organ regeneration as well as methods of establishing such micro organoids and/or micro tissue in the self-contained circulation system.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: November 29, 2016
    Assignee: TISSUSE GMBH
    Inventors: Uwe Marx, Gerd Lindner, Reyk Horland, Silke Hoffmann, Roland Lauster
  • Patent number: 9168809
    Abstract: An air conditioning system is provided, particularly for a vehicle having a main air conditioning unit, an auxiliary air conditioning unit, wherein both the main air conditioning unit and the auxiliary air conditioning unit contain a blower, an evaporator and a heater core, a cold pass is attached to the evaporator, a hot pass is affiliated to the heater core and the cold pass is separated from the hot pass by at least one temperature door. By an air conditioning system, especially for a vehicle, which uses the conditioned air in the vehicle cabin for engine cooling, an additional pass is arranged before the heater core in the auxiliary air conditioning unit wherein said hot pass ends in a body exhauster during the cooling mode of said auxiliary air conditioning unit.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: October 27, 2015
    Assignee: MAHLE International GmbH
    Inventors: Bjoern Gerd Lindner, Barbara Ruhland-Lindner
  • Publication number: 20140370070
    Abstract: The present invention relates to a method for producing hair microfollicles comprising the steps of: a) providing de novo papillae, b) providing other cell populations selected from the group of fibroblasts, keratinocytes and melanocytes, and co-culturing the de novo papillae with at least one other cell population in non-adherent culture vessels. The present invention relates also to methods of producing de novo papillae usable in said method for producing hair microfollicles.
    Type: Application
    Filed: August 26, 2014
    Publication date: December 18, 2014
    Inventors: Gerd LINDNER, Roland LAUSTER
  • Patent number: 8841124
    Abstract: The present invention relates to a method for producing hair microfollicles comprising the steps of: a) providing de novopapillae, b) providing other cell populations selected from the group of fibroblasts, keratinocytes and melanocytes, and co-culturing the de novopapillae with at least one other cell population in non-adherent culture vessels. The present invention relates also to methods of producing de novo papillae usable in said method for producing hair microfollicles.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: September 23, 2014
    Assignee: Technische Universitat Berlin
    Inventors: Gerd Lindner, Roland Lauster
  • Publication number: 20130295598
    Abstract: A self-contained circulation system, which supports the formation of capillaries in capillary growth sections and allows the formation of micro organoids and/or micro tissue sections for monitoring the effect of one or more test compounds and determining efficacy, side-effects, biosafety, metabolites, mode of action or organ regeneration as well as methods of establishing such micro organoids and/or micro tissue in the self-contained circulation system.
    Type: Application
    Filed: August 5, 2011
    Publication date: November 7, 2013
    Applicant: TECHNISCHE UNIVERSITAET BERLIN
    Inventors: Uwe Marx, Gerd Lindner, Reyk Horland, Silke Hoffman, Roland Lauster
  • Publication number: 20110086079
    Abstract: The present invention relates to a method for producing hair microfollicles comprising the steps of: a) providing de novopapillae, b) providing other cell populations selected from the group of fibroblasts, keratinocytes and melanocytes, and co-culturing the de novopapillae with at least one other cell population in non-adherent culture vessels. The present invention relates also to methods of producing de novo papillae usable in said method for producing hair microfollicles.
    Type: Application
    Filed: March 23, 2009
    Publication date: April 14, 2011
    Inventors: Gerd Lindner, Roland Lauster
  • Publication number: 20110033287
    Abstract: A blower assembly for use with an HVAC module is provided. The blower assembly includes a scroll or volute shaped housing having an air inlet in a wall of the housing for receiving air to be blown by an impeller, and an air outlet from which the blown air passes from the housing. A blower wheel is secured to a rotatable motor-driven shaft extending along a central axis of the air inlet. At least one venture is provided adjacent to the air inlet of the housing, the at least one venturi connectable to an aspirator that is in fluid communication with a sensor unit. Wherein, during operation, the blower wheel pulls air both through the air inlet to the housing and through the at least one venturi.
    Type: Application
    Filed: August 10, 2009
    Publication date: February 10, 2011
    Inventors: Bjoern Gerd Lindner, Stefan Scherer, Greg Rademacher
  • Publication number: 20080199311
    Abstract: A blower scroll comprising a base and a wall extending from an outer edge of the base. The base may include an outlet formed in the base a diverting device extending about at least a portion of the outlet. The diverting device may obstruct the flow of water droplets in the blower scroll into the outlet.
    Type: Application
    Filed: January 29, 2008
    Publication date: August 21, 2008
    Inventors: Bjoern Gerd LINDNER, Thomas Adler, David Merrow, Vasile Hasnas