Abstract: A device and a process detect a leak during artificial ventilation of a patient. A measurement system with a sensor arrangement and a sensor fluid guide unit is monitored. A fluid connection is established between a patient-side coupling unit and a medical device with a patient fluid guide unit. A gas sample is branched off from the patient fluid guide unit and guided through the sensor fluid guide unit to the sensor arrangement. A thermal conductivity time course of the gas sample reaching the sensor arrangement is determined with sensor arrangement measured values. Depending on a temporal change in the determined thermal conductivity, a decision is made as to whether there is an indication of a leak between the patient's fluid-guiding unit and the sensor arrangement. The leak establishes a fluid connection between the sensor fluid guide unit and/or the sensor arrangement and the environment.

Abstract: The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to amplified epidermal growth factor receptor (EGFR) and to the de2-7 EGFR truncation of the EGFR. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof.

Abstract: The invention relates to a loudspeaker, preferably a planar loudspeaker, comprising a tone panel (10), a holder (12), at least one drive unit (14), preferably fastened to the holder (12), for driving the tone panel (10), the drive unit (14) having a coil body (20) with a coil, and having a magnet device (16), the tone panel (10) having a curvature and/or arching and an end face of the coil body (20) fixed to the tone panel (10) being adapted to the shape of the curvature and/or arching.

Abstract: A gas measuring device (1000) for determining the concentration of a gas component in a breathing gas mixture includes a radiation source (1) with a illuminant (2) and a mirror arrangement (3) for emitting light radiation. A sample gas cuvette (5) is formed as a hollow body. A detector arrangement (15) with at least two bandpass filter elements (17, 18) and at least two detector elements (20, 21) receives the filtered light radiation. A control unit (42) is configured to detect signals from the detector elements (20, 21) and determine a concentration of a gas component in the breathing gas mixture. A light guide element (11) is provided in the form of a hollow body.

Abstract: A process (10), with a computer program, a device (30) and a ventilation system (40) detect a leak in a patient gas module, which suctions and analyzes a continuous sample gas stream from a ventilated patient (20), in a ventilation system for ventilating a patient (20). The process includes a determination (12) of a first time curve of a carbon dioxide concentration in a breathing gas mixture of the patient (20) and the determination (14) of a second time curve of a concentration of another gas in the breathing gas mixture, which gas is different from carbon dioxide. The process (10) further includes a determination (16) of a statistical similarity indicator between the first time curve and the second time curve and the detection (18) of the leak based on the similarity indicator.

Abstract: A photoacoustic sensor (100) is capable of detecting a predefined target gas in an area (Um). A process is capable of detecting the target gas with the use of such a sensor (100). A sample chamber (3) holds a gas sample (Gp) to be tested. Electromagnetic waves (eW) from a radiation source (1) pass through the sample chamber (3) and the detection chamber (4). The waves elicit in the detection chamber (4) an acoustic effect, which is measured by an acoustic sensor (7). The acoustic effect is correlated with the concentration of the target gas in the sample chamber (3). The detection chamber (4) is fluid-tightly sealed, is free from target gas and is filled with a replacement gas (Eg). The transmission of the replacement gas (Eg) has a spectral response similar to that of the transmission of the target gas in a predefined target gas wavelength range.

Abstract: Planar loudspeaker comprising a planar sound panel (10), a mounting (12), at least one drive unit (14) for driving the sound panel (10), said drive unit preferably being attached to the mounting (12), and at least one stabilizing device (22) for stabilizing a movement of the sound panel (10), wherein the stabilizing device (22) is arranged between the sound panel (10) and the mounting (12) and comprises at least a stroke section (28), which is configured so as to be movable, flexible and/or elastic, and at least one centering device (36) for centering the sound panel (10) and/or at least a part of the drive unit (14), wherein the centering device (36) is arranged in a different plane than the stabilizing device (22) and comprises at least a stroke section (28), which is configured so as to be movable, flexible and/or elastic.

Abstract: A photoacoustic sensor (100) is capable of detecting a predefined target gas in an area (Um). A process is capable of detecting the target gas with the use of such a sensor (100). A sample chamber (3) holds a gas sample (Gp) to be tested. Electromagnetic waves (eW) from a radiation source (1) pass through the sample chamber (3) and the detection chamber (4). The waves elicit in the detection chamber (4) an acoustic effect, which is measured by an acoustic sensor (7). The acoustic effect is correlated with the concentration of the target gas in the sample chamber (3). The detection chamber (4) is fluid-tightly sealed, is free from target gas and is filled with a replacement gas (Eg). The transmission of the replacement gas (Eg) has a spectral response similar to that of the transmission of the target gas in a predefined target gas wavelength range.

Abstract: Embodiments create an arrangement and a method for analyzing a fluid. The arrangement (10) for analyzing a fluid comprises beam splitter and mixer optics (12) configured to spatially mix an optical signal and split the same into at least two spatial sub-beams and a flow cell (14) configured to spectrally influence at least the two spatial sub-beams (15a; 15b) by means of a probe of the fluid. The arrangement further comprises a measurement system (16) configured to measure the at least two spatially separated sub-beams (15a; 15b).

Abstract: Planar loudspeaker comprising a planar sound panel (10), a mounting (12), at least one drive unit (14) for driving the sound panel (10), said drive unit preferably being attached to the mounting (12), and at least one stabilizing device (22) for stabilizing a movement of the sound panel (10), wherein the stabilizing device (22) is arranged between the sound panel (10) and the mounting (12) and comprises at least a stroke section (28), which is configured so as to be movable, flexible and/or elastic, and at least one centering device (36) for centering the sound panel (10) and/or at least a part of the drive unit (14), wherein the centering device (36) is arranged in a different plane than the stabilizing device (22) and comprises at least a stroke section (28), which is configured so as to be movable, flexible and/or elastic.

Abstract: A process for monitoring a measuring system (110) for mechanical ventilation of a patient (20) is carried out while a fluid connection (40) is established between the patient (20) and a medical device (100). A gas sample is suctioned from the fluid connection (40) and is sent through a gas sensor fluid-guiding unit (52) to a gas sensor array (50). A time curve of the CO2 concentration and O2 concentration in the suctioned gas sample are determined. A concentration change curve of the change over time of the CO2 concentration and the O2 concentration are calculated. A search is made for a time period in which the two concentration change curves continuously have the same sign. Upon detecting such a time period it is checked whether a predefined first leak criterion is met. When this is the case, an indication of a leak (L) is detected.

Abstract: A process (10), with a computer program, a device (30) and a ventilation system (40) detect a leak in a patient gas module, which suctions and analyzes a continuous sample gas stream from a ventilated patient (20), in a ventilation system for ventilating a patient (20). The process includes a determination (12) of a first time curve of a carbon dioxide concentration in a breathing gas mixture of the patient (20) and the determination (14) of a second time curve of a concentration of another gas in the breathing gas mixture, which gas is different from carbon dioxide. The process (10) further includes a determination (16) of a statistical similarity indicator between the first time curve and the second time curve and the detection (18) of the leak based on the similarity indicator.

Abstract: A device 10 withdraws a breathing gas stream (A) from a ventilation system (B) and transports the breathing gas stream (A) to a gas analysis system (G). The device 10 has a tubular configuration with an inner side (41) and with an outer side (42) and includes two tube sections (11, 11?) and a drying stage (12, 14, 22) with an inner side (43, 43?) and with an outer side (44, 44?), and at least one liquid storage device (13, 21). The drying stage (12, 14, 22) includes a gas-tight and moisture-permeable material that transports moisture from the inner side (43, 43?) of the drying stage (12, 14, 22) through the gas-tight and moisture-permeable material to the outer side (42) of the tubular device (10). The drying stage (12, 14, 22) and/or the liquid storage device (13, 21) is arranged at least partially between the two tube sections (11, 11?).

Abstract: A cutter cassette for a packaging machine, the cutter cassette includes a blade shaft on which at least one longitudinal cutting blade is arranged. The blade shaft can be transferred in a reversible manner from a transporting position into an operating position by lowering the blade shaft relative to a housing. The lowering of the blade shaft takes place under gravitational force.

Abstract: Embodiments create an arrangement and a method for analyzing a fluid. The arrangement (10) for analyzing a fluid comprises beam splitter and mixer optics (12) configured to spatially mix an optical signal and split the same into at least two spatial sub-beams and a flow cell (14) configured to spectrally influence at least the two spatial sub-beams (15a; 15b) by means of a probe of the fluid. The arrangement further comprises a measurement system (16) configured to measure the at least two spatially separated sub-beams (15a; 15b).

Abstract: The present invention relates to a longitudinal cotter cassette having a blade shaft, on which at least one longitudinal cutting blade is arranged, wherein to blade shaft can be reversibly moved from a transport position to a making position by means of lowering relative so a housing. The present invention further relates to a packaging machine comprising the longitudinal cutter cassette according to the invention.

Abstract: A device 10 withdraws a breathing gas stream (A) from a ventilation system (B) and transports the breathing gas stream (A) to a gas analysis system (G). The device 10 has a tubular configuration with an inner side (41) and with an outer side (42) and includes two tube sections (11, 11?) and a drying stage (12, 14, 22) with an inner side (43, 43?) and with an outer side (44, 44?), and at least one liquid storage device (13, 21). The drying stage (12, 14, 22) includes a gas-tight and moisture-permeable material that transports moisture from the inner side (43, 43?) of the drying stage (12, 14, 22) through the gas-tight and moisture-permeable material to the outer side (42) of the tubular device (10). The drying stage (12, 14, 22) and/or the liquid storage device (13, 21) is arranged at least partially between the two tube sections (11, 11?).

Abstract: A lamp for automotive front lighting and a vehicle headlight comprising the lamp are described, as well as a method of manufacturing the lamp. The lamp 10 comprises a base 12 for mechanical and electrical connection to an automotive headlight 50. A burner 14 is fixed to the base 12 and comprises an enclosed transparent vessel 22. A first filament 34 is arranged within the vessel 22. A holding wire 30c is arranged within the vessel, and a baffle 40 is arranged proximate to the first filament 34 to partially shield light emitted from the first filament 34. The baffle 40 is fixed to the holding wire 30c. The transparent vessel 22 comprises a vessel wall including a cylindrical portion 24 surrounding the first filament 34. In order to obtain a lamp which may withstand vibration, the vessel wall comprises, within the cylindrical portion 24, a deformed material portion 38 which contacts the baffle 40 or the holding wire 30c. The deformed material portion 38 is shielded from the first filament 34 by the baffle 40.

Abstract: A starter for an internal combustion engine comprises a starter motor and a starter pinion which can be displaced transversely to the longitudinal axis of the motor. The starter pinion is rotatably mounted in an eccentric component which is connected in a rotationally fixed manner to a rotatable transmission component of a transmission that is disposed between the starter motor and the starter pinion.

Abstract: A lamp for automotive front lighting and a vehicle headlight comprising the lamp are described, as well as a method of manufacturing the lamp. The lamp 10 comprises a base 12 for mechanical and electrical connection to an automotive headlight 50. A burner 14 is fixed to the base 12 and comprises an enclosed transparent vessel 22. A first filament 34 is arranged within the vessel 22. A holding wire 30c is arranged within the vessel, and a baffle 40 is arranged proximate to the first filament 34 to partially shield light emitted from the first filament 34. The baffle 40 is fixed to the holding wire 30c. The transparent vessel 22 comprises a vessel wall including a cylindrical portion 24 surrounding the first filament 34. In order to obtain a lamp which may withstand vibration, the vessel wall comprises, within the cylindrical portion 24, a deformed material portion 38 which contacts the baffle 40 or the holding wire 30c. The deformed material portion 38 is shielded from the first filament 34 by the baffle 40.