Patents by Inventor Gerd Seibold

Gerd Seibold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10420637
    Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: September 24, 2019
    Assignee: Abbott Laboratories Vascular Enterprises Limited
    Inventors: Joost J. Fierens, Silvio R. Schaffner, Marc Gianotti, Gerd Seibold, Randolf von Oepen
  • Publication number: 20170086965
    Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
    Type: Application
    Filed: December 12, 2016
    Publication date: March 30, 2017
    Inventors: Joost J. Fierens, Silvio R. Schaffner, Marc Gianotti, Gerd Seibold, Randolf von Oepen
  • Patent number: 9517146
    Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: December 13, 2016
    Assignee: ABBOTT LABORATORIES VASCULAR ENTERPRISES LIMITED
    Inventors: Joost J. Fierens, Silvio R. Schaffner, Marc Gregory Gianotti, Gerd Seibold, Randolf von Oepen
  • Publication number: 20160244490
    Abstract: The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.
    Type: Application
    Filed: May 5, 2016
    Publication date: August 25, 2016
    Applicant: Evonik Degussa GmbH
    Inventors: Stephan Hans, Brigitte Bathe, Alexander Reth, Wilfried Claes, Reinhard Krämer, Gerd Seibold, Alexander Henrich
  • Patent number: 9359413
    Abstract: The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: June 7, 2016
    Assignee: Evonik Degussa GmbH
    Inventors: Stephan Hans, Brigitte Bathe, Alexander Reth, Wilfried Claes, Reinhard Krämer, Gerd Seibold, Alexander Henrich
  • Patent number: 9017376
    Abstract: Apparatus is provided for sealing a vascular puncture by causing a reduction in the circumference of the puncture tract through delivery of a closure agent into tissue surrounding the puncture tract. A resultant inflammatory response and volumetric increase cause the tissue to swell into the puncture tract, thereby sealing it.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: April 28, 2015
    Assignee: Abbott Laboratories Vascular Enterprises, Limited
    Inventors: Stevan Nielsen, Bodo Quint, Randolf Von Oepen, Kenneth J. Michlitsch, Gerd Seibold, Tommy Conzelmann, Ib Erling Joergensen
  • Publication number: 20140324157
    Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
    Type: Application
    Filed: July 3, 2014
    Publication date: October 30, 2014
    Inventors: Joost J. Fierens, Silvio R. Schaffner, Marc Gianotti, Gerd Seibold, Randolf von Oepen
  • Patent number: 8814926
    Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: August 26, 2014
    Assignee: Abbott Laboratories Vascular Enterprises Limited
    Inventors: Joost J. Fierens, Silvio R. Schaffner, Marc Gianotti, Gerd Seibold, Randolf von Oepen
  • Patent number: 8709074
    Abstract: A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: April 29, 2014
    Assignee: Edwards Lifesciences AG
    Inventors: Jan Otto Solem, Per-Ola Kimblad, Randolf von Oepen, Bodo Quint, Gerd Seibold, Kenneth J. Michlitsch, Suk-Woo Ha, Karl-Ludwig Eckert, Ib Joergensen, Stevan Nielsen
  • Publication number: 20130190856
    Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Apparatus and methods are also provided for use at a vessel branching. The present invention further involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such porous membranes are described in which a continuous fiber of polymer is extruded through a reciprocating extrusion head and deposited onto a substrate in a predetermined pattern. When cured, the polymeric material forms a stable, porous membrane suitable for a variety of applications, including reducing emboli release during and after stent delivery, and providing a source for release of bioactive substances to a vessel or organ and surrounding tissue.
    Type: Application
    Filed: March 13, 2013
    Publication date: July 25, 2013
    Applicant: Abbott Laboratories Vascular Enterprises Limited
    Inventors: Randolph von Oepen, Gerd Seibold, Silvio R. Schaffner, Marc G Gianotti, Joost J. Fierens, Erhard Huesler, Arik Zucker, Eric Marcoux, Philippe Nicaise, Sebastien Dubois
  • Patent number: 8303645
    Abstract: The present invention provides a stent comprising a tubular flexible body having a wall with a web structure that is expandable from a contracted delivery configuration to deployed configuration. The web structure comprises a plurality of neighboring web patterns, where each web patterns is composed of adjoining webs, and the web patterns are interconnected. Each adjoining web comprises a central section interposed between two lateral sections to form concave or convex configurations.
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: November 6, 2012
    Assignee: Abbott Laboratories Vascular Enterprises Limited
    Inventors: Randolf Von Oepen, Gerd Seibold
  • Publication number: 20120252075
    Abstract: The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.
    Type: Application
    Filed: April 3, 2012
    Publication date: October 4, 2012
    Applicant: Evonik Degussa GmbH
    Inventors: Stephan Hans, Brigitte Bathe, Alexander Reth, Wilfried Claes, Reinhard Krämer, Gerd Seibold, Alexander Henrich
  • Publication number: 20120165924
    Abstract: A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.
    Type: Application
    Filed: February 6, 2012
    Publication date: June 28, 2012
    Applicant: Edwards Lifesciences AG
    Inventors: Jan Otto Solem, Per-Ola Kimblad, Randolf von Oepen, Bodo Quint, Gerd Seibold, Kenneth J. Michlitsch, Suk-Woo Ha, Karl-Ludwig Eckert, Ib Joergensen, Stevan Nielsen
  • Patent number: 8147513
    Abstract: Apparatus is provided for sealing a puncture within a vessel or tissue to provide hemostasis, comprising a first disk coupled to either a second disk or a spring, and sealingly engaged to the vessel or tissue surrounding the puncture. At least the first disk is preferably configured to substantially conform to the profile of the vessel or tissue when deployed. In one embodiment, the disks may be released from engagement with the vessel or tissue to reposition the disks after deployment.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: April 3, 2012
    Assignee: Abbott Laboratories Vascular Enterprises Limited
    Inventors: Gerd Seibold, Kenneth J. Michlitsch, Randolf Von Oepen, Bodo Quint, Ib Erling Joergensen, Stevan Nielsen, Tommy Conzelmann
  • Patent number: 8118833
    Abstract: Apparatus is provided for sealing a puncture within a vessel or tissue to provide hemostasis, comprising a first disk coupled to either a second disk or a spring, and sealingly engaged to the vessel or tissue surrounding the puncture. At least the first disk is preferably configured to substantially conform to the profile of the vessel or tissue when deployed. In one embodiment, the disks may be released from engagement with the vessel or tissue to reposition the disks after deployment.
    Type: Grant
    Filed: July 25, 2003
    Date of Patent: February 21, 2012
    Assignee: Abbott Laboratories Vascular Enterprises Limited
    Inventors: Gerd Seibold, Kenneth J. Michlitsch, Randolf Von Oepen, Bodo Quint, Ib Erling Joergensen, Stevan Nielsen, Tommy Conzelmann
  • Patent number: 8114125
    Abstract: Apparatus is provided for sealing a puncture within a vessel or tissue to provide hemostasis, comprising a first disk coupled to either a second disk or a spring, and sealingly engaged to the vessel or tissue surrounding the puncture. At least the first disk is preferably configured to substantially conform to the profile of the vessel or tissue when deployed. In one embodiment, the disks may be released from engagement with the vessel or tissue to reposition the disks after deployment.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: February 14, 2012
    Assignee: Abbott Laboratories Vascular Enterprises Limited
    Inventors: Gerd Seibold, Kenneth J. Michlitsch, Randolf Von Oepen, Bodo Quint, Ib Erling Joergensen, Stevan Nielsen, Tommy Conzelmann
  • Patent number: 8109984
    Abstract: A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.
    Type: Grant
    Filed: January 4, 2006
    Date of Patent: February 7, 2012
    Assignee: Edwards Lifesciences AG
    Inventors: Jan Otto Solem, Per-Ola Kimblad, Randolf von Oepen, Bodo Quint, Gerd Seibold, Kenneth J. Michlitsch, Suk-Woo Ha, Karl-Ludwig Eckert, Ib Joergensen, Stevan Nielsen
  • Publication number: 20120027872
    Abstract: Apparatus is provided for sealing a vascular puncture by causing a reduction in the circumference of the puncture tract through delivery of a closure agent into tissue surrounding the puncture tract. A resultant inflammatory response and volumetric increase cause the tissue to swell into the puncture tract, thereby sealing it.
    Type: Application
    Filed: June 30, 2011
    Publication date: February 2, 2012
    Applicant: ABBOTT LABORATORIES VASCULAR ENTERPRISES, LTD.
    Inventors: Stevan Nielsen, Bodo Quint, Randolf Von Oepen, Kenneth J. Michlitsch, Gerd Seibold, Tommy Conzelmann, Ib Erling Joergensen
  • Patent number: 8088157
    Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: January 3, 2012
    Assignee: Abbott Laboratories Vascular Enterprises Limited
    Inventors: Joost J. Fierens, Silvio R. Schaffner, Marc Gianotti, Gerd Seibold, Randolf Von Oepen
  • Patent number: 8075616
    Abstract: A device for reshaping a cardiac valve (26), which is elongate and has such dimensions as to be insertable into a cardiac vessel (24). The device has two states, in a first state (K) of which the device has a shape that is adaptable to the shape of the vessel (24), and to the second state (k?) of which the device is transferable from said first state (K). Further, the device comprises a fixing means (22,23;22a,23a) for fixing the ends of the device within the vessel (24), when the device is first positioned therein, a shape-changing member (20;20a) for transferring the device to the second state (K?) by reshaping it, and a delay means (21;21a) for delaying said reshaping until the fixing of the ends of the device has been reinforced by keeping said device in said first state (K) until the delay means (21;21a) is resorbed.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: December 13, 2011
    Assignee: Edwards Lifesciences AG
    Inventors: Jan Otto Solem, Per Ola Kimblad, Randolf von Oepen, Bodo Quint, Gerd Seibold, Kenneth J. Michlitsch, Suk-Woo Ha, Karl-Ludwig Eckert, Ib Joergensen, Stevan Nielsen