Patents by Inventor Gerd-Uwe Flechsig

Gerd-Uwe Flechsig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170335474
    Abstract: The present invention relates to a method for producing at least one product by electrochemical synthesis on a directly electrically-heated working electrode (1), in which at least one educt reacts on the heated working electrode (1) to the at least one product. The invention also relates to the use of a directly electrically-heated working electrode (1) for the electrochemical synthesis of at least one product. The invention relates in particular to a working electrode (1), particularly in the form of a three-dimensional, preferably conical spiral, designed for the electrochemical synthesis. Another object of the invention is the synthesis/regeneration of an enzymatic cofactor on a working electrode (1) according to the invention.
    Type: Application
    Filed: September 25, 2015
    Publication date: November 23, 2017
    Inventor: Gerd-Uwe FLECHSIG
  • Patent number: 9823215
    Abstract: This invention relates to an electrochemical sensor (1), comprising a base element (3), which is made of electrically insulating material and has a planar surface (9), and a pair of conductors (5), which are attached to said planar surface (9) of the base element (3), wherein the two conductors (5) of the pair are connected by at least one wire-shaped electrochemical working electrode (7). The invention further related to a sensor array (21), which has several previously described sensors (1), and to a method for coating a working electrode (7) of the previously described sensor (1).
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: November 21, 2017
    Assignee: Gensoric GmbH
    Inventors: Gerd-Uwe Flechsig, Anne Walter, Martin Jacobsen
  • Patent number: 9273348
    Abstract: The invention includes a method and array for replicating and analyzing one or a plurality of different target sequences in nucleic acid samples. The different reactions for replicating the target sequences occur simultaneously on an array with selectively heatable array elements with their reaction surfaces, some of which have been modified differently, and in the sample solution disposed thereabove. The target sequences are analyzed using molecular detection on reaction surfaces of said array that have been modified with probe strands. The target strands are replicated and analyzed simultaneously, successively, or alternately.
    Type: Grant
    Filed: February 10, 2006
    Date of Patent: March 1, 2016
    Assignee: Universitaet Rostock
    Inventors: Gerd-Uwe Flechsig, Joerg Peter
  • Publication number: 20140326618
    Abstract: This invention relates to an electrochemical sensor (1), comprising a base element (3), which is made of electrically insulating material and has a planar surface (9), and a pair of conductors (5), which are attached to said planar surface (9) of the base element (3), wherein the two conductors (5) of the pair are connected by at least one wire-shaped electrochemical working electrode (7). The invention further related to a sensor array (21), which has several previously described sensors (1), and to a method for coating a working electrode (7) of the previously described sensor (1).
    Type: Application
    Filed: August 1, 2012
    Publication date: November 6, 2014
    Inventors: Gerd-Uwe Flechsig, Anne Walter, Martin Jacobsen
  • Publication number: 20140228247
    Abstract: The invention relates to a method for the sequence-specific analysis of nucleic acids in a sample in which the nucleic acid is present at least partially as a double strand, which method uses electrochemical detection methods (e.g. with [OsO4(bipy)]). In particular, the methods comprise steps in which the at least partially double-stranded nucleic acid strands are converted by thermal denaturation to single strands which are termed target strands, and at least one nucleic acid strand designated protective strand is added, which protective strand can hybridize with a target strand, in order to form partial double-stranded segments, wherein the protective strands are shorter than the target strands, wherein the temperature of the sample is rapidly lowered to a temperature of below 5° C., preferably below 0° C.
    Type: Application
    Filed: September 25, 2012
    Publication date: August 14, 2014
    Applicant: Universitat Rostock
    Inventors: Gerd-Uwe Flechsig, Maren Mix, Simone Krüger
  • Patent number: 8216446
    Abstract: The invention relates to a method of labelling and analysing nucleic acids. More specifically, the invention relates to a method of analysing nucleic acids, which comprises contacting the nucleic acids to be detected, which are in the form of single-stranded nucleic acid strands partially (i.e. over a part of the total length of the nucleic acid strands) hybridized with protective strands, with substances which specifically react with nucleobases of the single-stranded sections of the nucleic acid strands, and which are capable of subsequently participating in a reversible redox reaction in electroanalytical processes known to the skilled worker.
    Type: Grant
    Filed: August 17, 2006
    Date of Patent: July 10, 2012
    Assignee: Universität Rostock
    Inventors: Gerd-Uwe Flechsig, Thomas Reske
  • Patent number: 8211291
    Abstract: A sensor apparatus for an electrochemical measuring device. The apparatus has at least one electrode, which can be heated using a heating current in the form of an alternating current, and a first and a second connection for the supply line for the heating current. The electrochemical measuring device is connected to the electrode by a third connection. In this case, the apparatus has the third connection connected to the electrode by a bridge circuit, which is also connected to the first and second connections. There also is provided a method for carrying out electrochemical measurements at elevated temperature. The sensor apparatus and the method for carrying out electrochemical measurements enable electrochemical measurements with little interference and directly heated electrodes in conjunction with a simplified design of the electrodes.
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: July 3, 2012
    Assignee: Universitaet Rostock
    Inventors: Gerd-Uwe Flechsig, Jan Gimsa, Peter Gründler, Harald Grabow
  • Publication number: 20090184001
    Abstract: A sensor apparatus for an electrochemical measuring device. The apparatus has at least one electrode, which can be heated using a heating current in the form of an alternating current, and a first and a second connection for the supply line for the heating current. The electrochemical measuring device is connected to the electrode by a third connection. In this case, the apparatus has the third connection connected to the electrode by a bridge circuit, which is also connected to the first and second connections. There also is provided a method for carrying out electrochemical measurements at elevated temperature. The sensor apparatus and the method for carrying out electrochemical measurements enable electrochemical measurements with little interference and directly heated electrodes in conjunction with a simplified design of the electrodes.
    Type: Application
    Filed: February 6, 2007
    Publication date: July 23, 2009
    Applicant: UNIVERSITÄT ROSTOCK
    Inventors: Gerd-Uwe Flechsig, Jan Gimsa, Peter Gründler, Harald Grabow
  • Publication number: 20080269066
    Abstract: The invention includes a method and array for replicating and analyzing one or a plurality of different target sequences in nucleic acid samples. The different reactions for replicating the target sequences occur simultaneously on an array with selectively heatable array elements with their reaction surfaces, some of which have been modified differently, and in the sample solution disposed thereabove. The target sequences are analyzed using molecular detection on reaction surfaces of said array that have been modified with probe strands. The target strands are replicated and analyzed simultaneously, successively, or alternately.
    Type: Application
    Filed: February 10, 2006
    Publication date: October 30, 2008
    Inventors: Gerd-Uwe Flechsig, Joerg Peter