Abstract: A system and method is provided for creating motion-adjusted or motion-compensated images of a patient to guide an interventional medical procedure. The method includes displaying a static roadmap and a plurality of dynamic images to show the interventional medical device aligned on the static roadmap using a motion transformation. Alignment of the interventional medical device on the static roadmap is based on a user selection of one of motion compensation of the interventional medical device relative to the static roadmap to produce a plurality of images that do not show patient motion or motion adjustment of the static roadmap relative to the interventional medical device to produce a plurality of images that show patient motion.

Abstract: A system and method is provided for creating motion-adjusted or motion-compensated images of a patient to guide an interventional medical procedure. The method includes displaying a static roadmap and a plurality of dynamic images to show the interventional medical device aligned on the static roadmap using a motion transformation. Alignment of the interventional medical device on the static roadmap is based on a user selection of one of motion compensation of the interventional medical device relative to the static roadmap to produce a plurality of images that do not show patient motion or motion adjustment of the static roadmap relative to the interventional medical device to produce a plurality of images that show patient motion.

Abstract: The invention relates to a reaction vessel, a device and a method for detecting specific interactions between molecular target and probe molecules. The present invention especially relates to a reaction vessel which has a shape and size typical of a laboratory reaction vessel and in which a supporting element with probe molecules immobilised thereon on predetermined regions is arranged on its base surfaces.

Abstract: The invention relates to a reaction vessel, a device and a method for detecting specific interactions between molecular target and probe molecules. The present invention especially relates to a reaction vessel which has a shape and size typical of a laboratory reaction vessel and in which a supporting element with probe molecules immobilized thereon on predetermined regions is arranged on its base surfaces.

Abstract: The present invention relates to compounds and their use in competitive protein binding assays, for example for use with glycosyl transferase and/or glycoprocessing proteins. The present application also provides kits and apparatuses for use in the assays. In particular, the present invention provides a compound of the formula (I): wherein n is 1, 2 or 3; R1 is selected from —OH, —OPO3H, —OR4, —NHR4, R6; R2 and R3 are each independently selected from —H, —OH, optionally substituted —O-alkyl and —O-alkanoyl; R4 is selected from an optionally substituted mono or polysaccharide, -alkyl, -alkenyl, -alkynyl, and L-Z, where L is a linking agent and Z is a binding agent; R6 is an optionally substituted hydrocarbon group; A is either (i) a substituted heteroaryl group, the substituent on the heteroaryl group having a double bond conjugated to the heteroaryl group, or (ii) a substituted aryl group, the substituent on the aryl group having a double bond conjugated to the aryl group.

Abstract: The present invention relates to compounds and their use in competitive protein binding assays, for example for use with glycosyl transferase and/or glycoprocessing proteins. The present application also provides kits and apparatuses for use in the assays. In particular, the present invention provides a compound of the formula (I): wherein n is 1, 2 or 3; R1 is selected from —OH, —OPO3H, —OR4, —NHR4, R6; R2 and R3 are each independently selected from —H, —OH, optionally substituted —O-alkyl and —O-alkanoyl; R4 is selected from an optionally substituted mono or polysaccharide, -alkyl, -alkenyl, -alkynyl, and L-Z, where L is a linking agent and Z is a binding agent; R6 is an optionally substituted hydrocarbon group; A is either (i) a substituted heteroaryl group, the substituent on the heteroaryl group having a double bond conjugated to the heteroaryl group, or (ii) a substituted aryl group, the substituent on the aryl group having a double bond conjugated to the aryl group.

Abstract: The invention relates to a method for genotyping and pathotyping bacteria of the species Pseudomonas aeruginosa by means of hybridization assays on a biochip or microarray. The invention further relates to specific oligonucleotide probes, which can be employed within the scope of the detection method, as well as to biochips having such oligonucleotide probes.

Abstract: The invention relates to a reaction vessel, a device and a method for detecting specific interactions between molecular target and probe molecules. The present invention especially relates to a reaction vessel which has a shape and size typical of a laboratory reaction vessel and in which a supporting element with probe molecules immobilised thereon on predetermined regions is arranged on its base surfaces.

Abstract: The invention relates to a method for qualitatively and/or quantitatively detecting certain molecular targets using probe arrays. The inventive detection method comprises a reaction which delivers a product with a particular solubility product, this solubility product causing the precipitation or the formation of a precipitate of the product on an array element of the probe array on which an interaction has taken place between the probe and the target.