Patents by Inventor Gerd Walz
Gerd Walz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11046932Abstract: The present invention relates to a method for producing renal cells, comprising overexpressing Hnf1b and Pax8, and optionally Hnf4a and/or Emx2 in differentiated cells.Type: GrantFiled: January 25, 2017Date of Patent: June 29, 2021Assignee: Albert-Ludwigs-Universitaet FreiburgInventors: Soeren Lienkamp, Michael Kaminski, Sebastian Arnold, Gerd Walz
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Publication number: 20190071646Abstract: The present invention relates to a method for producing renal cells, comprising overexpressing Hnf1b and Pax8, and optionally Hnf4a and/or Emx2 in differentiated cells.Type: ApplicationFiled: January 25, 2017Publication date: March 7, 2019Applicant: Albert-Ludwigs-Universitaet FreiburgInventors: Soeren LIENKAMP, Michael KAMINSKI, Sebastian ARNOLD, Gerd WALZ
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Publication number: 20110229895Abstract: The present invention relates to the diagnosis of renal disorders, in particular of polycystic kidney disease (PKD). The invention provides methods for diagnosing or monitoring the progression of PKD and test kits useful in those methods.Type: ApplicationFiled: January 17, 2007Publication date: September 22, 2011Inventor: Gerd Walz
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Patent number: 6613746Abstract: Disclosed is a method of inhibiting the binding of a cell bearing a cell adhesion protein to a molecule or cell bearing a carbohydrate determinant specific for the cell adhesion molecule. The method involves contacting the cell adhesion protein-bearing cell with an AGP-antibody bearing the carbohydrate determinant. Also disclosed are AGP-antibody fusion proteins to which are covalently bonded carbohydrate moieties which interfere with the antibody portion's ability to fix complement and bind an Fc receptor. The methods of the invention may be used, for example, in any antibody-based therapy, for example, to reduce inflammation.Type: GrantFiled: June 7, 1995Date of Patent: September 2, 2003Assignee: The General Hospital CorporationInventors: Brian Seed, Gerd Walz
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Patent number: 6156881Abstract: Disclosed is a method of inhibiting the binding of a cell bearing a cell adhesion protein to a molecule or cell bearing a carbohydrate determinant specific for the cell adhesion molecule. The method involves contacting the cell adhesion protein-bearing cell with an inhibitor molecule bearing the carbohydrate determinant. Also disclosed is a method of inhibiting the binding of the first member of a specific binding pair to the second member of the specific binding pair, involving contacting the first member with an antibody which is specific for the first member and which is covalently bonded to a carbohydrate moiety which interferes with the antibody's ability to fix complement and bind an F.sub.c receptor. The methods of the invention may be used, for example, to reduce inflammation.Type: GrantFiled: January 12, 1999Date of Patent: December 5, 2000Assignee: The General Hospital CorporationInventors: Brian Seed, Gerd Walz
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Patent number: 5977247Abstract: An aqueous coating composition useful as electro-deposition coatings includes (A') an aqueous dispersion of a resin (A) having functional groups which are reactive toward isocyanate, and (B') an aqueous, solvent-free dispersion of a solubilized masked polyisocyanate (B). The coating is cured by baking at a temperature which regenerates the isocyanate groups.Type: GrantFiled: October 3, 1997Date of Patent: November 2, 1999Assignee: Vianova Resins GmbH & Co. KGInventors: Markus A. Schafheutle, Achim Voelker, Susanne Wehner, Gerd Walz
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Patent number: 5932636Abstract: Aqueous synthetic resin dispersions comprising (A) an ionic resin, based on aralkylated epoxy resins, (B) a blocked polyisocyanate and (C) a polymer of at least one olefinically unsaturated monomer which is capable of undergoing free-radical polymerization are useful, for example, as binders in processes of coating by electrodeposition.Type: GrantFiled: April 30, 1997Date of Patent: August 3, 1999Assignee: Vianova Resins GmbHInventors: Uwe Neumann, Michael Hoenel, Achim Voelker, Gerd Walz, Susanne Wehner, Peter Ziegler
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Patent number: 5858983Abstract: Disclosed is a method of inhibiting the binding of a cell bearing a cell adhesion protein to a molecule or cell bearing a carbohydrate determinant specific for the cell adhesion molecule. The method involves contacting the cell adhesion protein-bearing cell with an inhibitor molecule bearing the carbohydrate determinant. Also disclosed is a method of inhibiting the binding of the first member of a specific binding pair to the second member of the specific binding pair, involving contacting the first member with an antibody which is specific for the first member and which is covalently bonded to a carbohydrate moiety which interferes with the antibody's ability to fix complement and bind an F.sub.c receptor. The methods of the invention may be used, for example, to reduce inflammation.Type: GrantFiled: June 5, 1995Date of Patent: January 12, 1999Assignee: The General Hospital CorporationInventors: Brian Seed, Gerd Walz
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Patent number: 5859169Abstract: Urethane-modified novolaks which are prepared by simultaneous reaction of a monohydric or polyhydric phenol (A) with an oxo compound (aldehyde or ketone) (B) and a urethane (C) in the presence of an acidic catalyst (D) at an elevated temperature of 60.degree. to 200.degree. C. and contain no interfering amounts of free starting phenol, and their use as adhesion improvers in rubbers, in particular rubbers containing reinforcing media such as steel cord or textile fibers.Type: GrantFiled: September 8, 1997Date of Patent: January 12, 1999Assignee: Vianora Resins GmbHInventors: Thomas Burkhart, Siegfried Wallenwein, Gerhard Brindoepke, Gerd Walz
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Patent number: 5801044Abstract: Disclosed is a method of inhibiting the binding of a cell bearing a cell adhesion protein to a molecule or cell bearing a carbohydrate determinant specific for the cell adhesion molecule. The method involves contacting the cell adhesion protein-bearing cell with an inhibitor molecule bearing the carbohydrate determinant. Also disclosed is a method of inhibiting the binding of the first member of a specific binding pair to the second member of the specific binding pair, involving contacting the first member with an antibody which is specific for the first member and which is covalently bonded to a carbohydrate moiety which interferes with the antibody's ability to fix complement and bind an F.sub.c receptor. The methods of the invention may be used, for example, to reduce inflammation.Type: GrantFiled: June 5, 1995Date of Patent: September 1, 1998Assignee: The General Hospital CorporationInventors: Brian Seed, Gerd Walz
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Patent number: 5723583Abstract: Disclosed is a method of inhibiting the binding of a cell bearing a cell adhesion protein to a molecule or cell bearing a carbohydrate determinant specific for the cell adhesion molecule. The method involves contacting the cell adhesion protein-bearing cell with an inhibitor molecule bearing the carbohydrate determinant. Also disclosed is a method of inhibiting the binding of the first member of a specific binding pair to the second member of the specific binding pair, involving contacting the first member with an antibody which is specific for the first member and which is covalently bonded to a carbohydrate moiety which interferes with the antibody's ability to fix complement and bind an F.sub.c receptor. The methods of the invention may be used, for example, to reduce inflammation.Type: GrantFiled: June 7, 1995Date of Patent: March 3, 1998Assignee: The General Hospital CorporationInventors: Brian Seed, Gerd Walz
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Patent number: 5691425Abstract: Polyurethane dispersions prepared by polymerization, initiated by free radicals, of polyurethane macromonomers containing carboxyl, phosphonic acid or sulfonic acid groups and lateral vinyl groups and optionally terminal vinyl, hydroxyl, urethane, thiourethane and/or urea groups.These polyurethane dispersions are suitable for the production of coatings on substrates, as adhesives or as binders in printing inks.Type: GrantFiled: July 2, 1992Date of Patent: November 25, 1997Assignee: Hoechst AGInventors: Heinz-Peter Klein, Gerd Walz, Markus A. Schafheutle
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Patent number: 5646236Abstract: Polyesters obtained by reacting from 5 to 50 parts of at least one linear or branched, aliphatic or cycloaliphatic, at least dihydric alcohol, from 2 to 40 parts of at least one at least dibasic, aromatic carboxylic acid, from 0 to 40 parts of at least one 2-alkenyldicarboxylic anhydride, from 10 to 30 parts of at least one at least dibasic, linear or branched, aliphatic carboxylic acid, from 0 to 15 parts of an aliphatic, linear or branched hydroxy acid, from 0 to 15 parts of an aliphatic, linear or branched polyamine having at least one primary and at least one secondary or tertiary amino group, from 0 to 15 parts of a glycidyl ester of a branched, aliphatic monocarboxylic acid or of a glycidyl ether of a branched, aliphatic alcohol, and from 0 to 15 parts of polyhydroxyamine are useful, for example, as additives in coating compositions.Type: GrantFiled: January 30, 1995Date of Patent: July 8, 1997Assignee: Hoechst AktiengesellschaftInventors: Markus A. Schafheutle, Achim Voelker, Susanne Wehner, Gerd Walz, Joachim Zoeller
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Patent number: 5620751Abstract: Binders for powder coatings comprising A) a solid unsaturated polyester and B) a polyurethane comprising (meth)acryloyl groups. These polyester-containing mixtures are distinguished by an improved blocking stability compared with polyurethane alone.Type: GrantFiled: March 14, 1996Date of Patent: April 15, 1997Assignee: Hoechst AktiengesellschaftInventors: Gerhard Brindoepke, Dietmar Fink, Gerd Walz
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Patent number: 5589535Abstract: An aqueous coating composition containing at least one water-dispersible polyurethane resin containing air-drying groups and optionally further binder resins and conventional paint additives, which polyurethane resin contains structural units derived from(A) polyisocyanates,(B) polyols containing air-drying groups,(C) optionally polyols which are free of air-drying groups,(D) compounds having at least two groups which are reactive with isocyanate groups and at least one group capable of anion formation,(E) optionally monoalcohls containing air-drying groups,(F) and/or compounds which differ from (B), (C), (D) and (E) and contain at least one group which is reactive with NCO groups, which has excellent pigment compatibility and the coatings produced therefrom have good corrosion protection and good mechanical properties even in the absence of siccatives.Type: GrantFiled: May 30, 1995Date of Patent: December 31, 1996Assignee: Hoechst AktiengesellschaftInventors: Michael Schwab, Gerd Walz, Gerhard Merten
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Patent number: 5580908Abstract: Polymer mixtures comprising at least one amino group-containing polymer A) and at least one polymer B) of ethylenically unsaturated monomers, which mixtures are obtained by reacting an epoxide with an amine in the presence of the ethylenically unsaturated monomers, and then arrying out free-radical polymerization. These polymer mixtures are employed for the preparation of binder vehicles for water-based printing inks and print varnishes.Type: GrantFiled: August 15, 1995Date of Patent: December 3, 1996Assignee: Hoechst AktiengesellschaftInventors: Astrid Giencke, Robert Kiehl, Gerd Walz, Bernd Mergardt
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Patent number: 5565508Abstract: Aqueous synthetic resin dispersions comprising A) an ionic resin, preferably a cationic resin, B) a blocked polyisocyanate and C) a polymer of at least one ethylenically unsaturated monomer which can be polymerized by free-radical polymerization. These synthetic resin dispersions are used as binders in electrodeposition coating baths.Type: GrantFiled: April 23, 1994Date of Patent: October 15, 1996Assignee: Hoechst AktiengesellschaftInventors: Michael Hoenel, Achim Voelker, Gerd Walz, Peter Ziegler
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Patent number: 5545678Abstract: Amino-containing polymer systems which are suitable for the preparation of binders for printing inks can be obtained by synthesizing a polymer or polymer mixture A from at least one compound from each of the groups(a) epoxides, carbonates, epoxide-carbonates,(b) amines and(c) phenols,at least partial neutralization of the resulting polymer or polymer mixture A, and transfer to water, and optionally, preparing a water-insoluble polymer B which can be prepared by polymerization of ethylenically unsaturated monomers in the presence of the polymer or polymer mixture A.Type: GrantFiled: November 2, 1994Date of Patent: August 13, 1996Assignee: Hoechst AktiengesellschaftInventors: Astrid Giencke, Uwe Neumann, Bernd Mergardt, Gerd Walz
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Patent number: 5525666Abstract: Solvent-free aqueous synthetic-resin dispersions comprising a polymer (A) which is obtained by polymerization of (A1) capped polyisocyanates in which some of the capping groups contain an ethylenically unsaturated group, and (A2) ethylenically unsaturated monomers in the presence of an ionic resin (B). The resin is useful in electrodeposition coatings.Type: GrantFiled: August 29, 1994Date of Patent: June 11, 1996Assignee: Hoechst AktiengesellschaftInventors: Michael Hoenel, Markus A. Schafheutle, Achim Voelker, Gerd Walz, Susanne Wehner, Peter Ziegler
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Patent number: 5521267Abstract: Emulsifier-free synthetic resins and mixtures of synthetic resins with water are used as binders for water-borne printing inks and printing varnishes. The resins contain: (a) a polymer resin A containing acid groups which may have been neutralized or partially neutralized and can be prepared by in-situ polymerization of ethylenically unsaturated compounds containing acid groups with further ethylenically unsaturated compounds and condensation with monohydroxy compounds and, if desired, neutralization or partial neutralization, and (b) if desired, a water-insoluble polymer resin B in the form of latex particles which can be prepared by emulsion polymerization of ethylenically unsaturated compounds in the presence of the polymer resin A.Type: GrantFiled: September 6, 1994Date of Patent: May 28, 1996Assignee: Hoechst AktiengesellschaftInventors: Astrid Giencke, Petra Ulrich, Gerd Walz, Bernd Mergardt