Patents by Inventor Gergely Héja

Gergely Héja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4393008
    Abstract: 2-(3-phenoxy-phenyl)-propionic acid or its pharmaceutical treatments, are prepared by hydrolyzing and partially decarboxylating ##STR1## wherein R=C.sub.1 -C.sub.6 alkyl or amino, the latter compounds being themselves new and, where R=C.sub.1 -C.sub.6 alkyl, have antiinflammatory pharmaceutical properties.
    Type: Grant
    Filed: August 12, 1981
    Date of Patent: July 12, 1983
    Assignee: Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt
    Inventors: Endre Palosi, Gergely Heja, Dezso Korbonits, Pal Kiss, Csaba Gunczi, Judit Cser, Ida Szvoboda, Gabor Szabo, Tamas Kallay, Laszlo Ledniczky, Maria Szomor
  • Patent number: 4391821
    Abstract: The present invention relates to novel 7-substituted benzopyranes of formula (I), whereinR.sub.1 and R.sub.2 are hydrogen, alkyl of from 1 to 6 carbon atoms, hydroxyalkyl, alkenyl, cycloalkyl, phenylalkyl, dimethoxy-phenylalkyl, or R.sub.1 and R.sub.2 together with the joining nitrogen atom may represent a 5-7-membered heterocyclic ring,R.sub.3 is hydrogen, alkyl of from 1 to 4 carbon atoms or phenyl,R.sub.4 is hydrogen,R.sub.5 is hydrogen or phenyl, orR.sub.4 and R.sub.5 together may represent a bonding electron pair between the second and the third carbon atoms of the benzopyrane ring,R.sub.6 and R.sub.7 are hydrogen or they may represent an oxygen atom together,n is 1 or 2,with the proviso, that the pyrane ring may bear only one alkyl or phenyl substituent, and preparation process thereof.The novel compounds have valuable therapeutical effects, mainly in cardiotherapy.
    Type: Grant
    Filed: July 17, 1981
    Date of Patent: July 5, 1983
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Dezso Korbonits, Mihaly Nogradi, Borbala Vermes nee Szluha, Janos Strelisky, Andras Wolfner, Gergely Heja, Gabor Kovacz, Jozsef Szegi, Sandor Virag
  • Patent number: 4385004
    Abstract: New compounds of the formula (VIIIa) are disclosed ##STR1## wherein R.sup.1 is hydrogen, methyl or ethyl;R.sup.2 is hydrogen, fluoro, or alkyl having 1 to 4 carbon atoms;R.sup.3 is hydrogen, phenyl, alkoxy having 1 to 6 carbon atoms; phenoxy, thenoyl, or benzoyl; orR.sup.2 and R.sup.3 together with the phenyl group to which they are attached form a naphthyl group which is unsubstituted or substituted by C.sub.1 to C.sub.4 alkyl or C.sub.1 to C.sub.4 alkoxy;R.sup.10 is phenylaminocarbonyl, 1-phenyl-5-tetrazolyl, a group --SO.sub.2 OMe, wherein Me is a metal atom selected from the group which consists of sodium or potassium, or a group --SO.sub.2 R.sup.6 in which R.sup.6 is alkyl having 1 to 4 carbon atoms, 4-methylphenyl, amino, C.sub.1 to C.sub.4 alkoxycarbonyl-amino, or benzoylamino, or R.sup.10 is a group ##STR2## in which R.sup.7 is cycloalkyl having 5 to 6 carbon atoms, and R is vinyl. The compounds are intermediates useful in the preparation of arylacetic acids having antiinflammatory compounds.
    Type: Grant
    Filed: March 23, 1981
    Date of Patent: May 24, 1983
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Endre Palosi, Dezso Korbonits, Pal Kiss, Csaba Gonczy, Gergely Heja, Judit Cser nee Kun, Rudolf Szebeni, Maria Szomor nee Wundele, Ida Szvoboda nee Kanzel
  • Patent number: 4317920
    Abstract: Arylacetic acid derivatives of the formula ##STR1## with R.sup.1, R.sup.2 and R.sup.3 specifically defined and which are useful as antirheumatic and antiinflammatory pharmaceuticals are practiced by catalytic hydrogenation of new compounds of the formula ##STR2## in which R and R.sup.10 are also specifically defined. The method of making the latter compound is also set forth.
    Type: Grant
    Filed: May 21, 1979
    Date of Patent: March 2, 1982
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Endre Palosi, Dezso Korbonits, Pal Kiss, Csaba Gonczy, Gergely Heja, Judit Cser nee Kun, Rudolf Szebeni, Maria Szomor nee Wundele, Ida Szvoboda nee Kanzel
  • Patent number: 4304938
    Abstract: 3-Phenoxybenzene derivatives are prepared by a method which comprises the steps of(a) chlorinating benzaldehyde with chlorine gas in the presence of a hydrocarbon and a Lewis acid catalyst to obtain 3-chlorobenzaldehyde; (b) reacting the 3-chlorobenzaldehyde with ethylene glycol to obtain 2-(3-chlorophenyl)-1,3-dioxolane; (c) etherifying said dioxolane with an alkali phenolate to yield the intermediate 2-(3-phenoxyphenyl)-1,3-dioxolane and converting this intermediate to the corresponding aldehyde, cyanohydrin, sulfonic acid salt or oxime derivative.
    Type: Grant
    Filed: December 21, 1979
    Date of Patent: December 8, 1981
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara RT
    Inventors: Endre Palosi, Gergely Heja, Dezso Korbonits, Pal Kiss, Csaba Gonczi, Judit Cser nee Kun, Ida Szvoboda nee Kauzel, Gabor Kovacs, Gabor Szabo, Tamas Kallay, Laszlo Ledniczky
  • Patent number: 4304930
    Abstract: 2-(3-Phenoxy-phenyl)-propionic acid or its pharmaceutical treatments, are prepared by hydrolyzing and partially decarboxylating ##STR1## wherein R=C.sub.1 -C.sub.6 alkyl or amino, the latter compounds being themselves new and, where R=C.sub.1 -C.sub.6 alkyl, have antiinflammatory pharmaceutical properties.
    Type: Grant
    Filed: December 21, 1979
    Date of Patent: December 8, 1981
    Assignee: Chinoin Gyogyszer- es Vegyeszeti Termekek Gyara Rt
    Inventors: Endre Palosi, Gergely Heja, Dezso Korbonits, Pal Kiss, Csaba Gonczi, Judit Cser nee Kun, Ida Szvoboda nee Kanzel, Gabor Szabo, Tamas Kallay, Laszlo Ledniczky, Maria Szomor nee Wundele
  • Patent number: 4259344
    Abstract: A process for the preparation of anthelmintic compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen or --COOR;R.sup.5 is C.sub.1 to C.sub.4 alkyl;R.sup.2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; andR.sup.4 is hydrogen, alkyl, cycloalkyl; alkenyl, alkynyl or aralkyl;or pharmaceutically acceptable salts thereof comprises subjecting a bis compound of the formula: ##STR2## to reduction to cleave the disulfide linkage and where R.sup.4 is other then hydrogen, subsequent reaction of the mercapto group. Intermediate compounds and a process for preparing same are also disclosed.
    Type: Grant
    Filed: June 22, 1979
    Date of Patent: March 31, 1981
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Csaba Gonczi, Dezso Korbonits, Pal Kiss, Endre Palosi, Gergely Heja, Ida Szvoboda nee Kanzel, Judit Cser nee Kun, Maria Szomor nee Wundele, Gyorgy Kormoczi, Andras Kelemen
  • Patent number: 4010193
    Abstract: A basic ester having the formula ##STR1## wherein Ac is benzoyl substituted by at least two substituents selected from the group which consist of halogen atoms, lower alkyl, lower alkoxy, hydroxy, nitro and sulfamoyl, and A B are hydrogen or lower alkyl or are cycloalkyl together. The compounds are therapeutic for cardic conditions.
    Type: Grant
    Filed: April 26, 1973
    Date of Patent: March 1, 1977
    Assignee: Chinoin Gyogyszer-es Vegyeszeti Termekek Gyara RT
    Inventors: Kalman Harsanyi, Laszlo Szekeres, Gergely Heja, Gyula Papp, Dezso Korbonits, Pal Kiss