Abstract: The methods and apparatus according to embodiments of the present invention provide substantially complete and rapid air cleaning and/or disinfection in the rooms that are substantially closed to outside air and have the typical complement and arrangement of furniture and people present, i.e. a “normal”environment. A study of air flow patterns in a variety of room configurations and arrangements demonstrates that EFA location within the room as well as furniture and people play a crucial role in air movement and airflow throughout the room, in minimizing or eliminating “dead spots” of stagnant air, and in achieving a goal of cleaning and disinfecting substantially all of the air.