Patents by Inventor Gergo Hegedus

Gergo Hegedus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of oligonucleotide sequencing by mass spectrometry
    Patent number: 8486707
    Abstract: A computer-implemented method for confirming the nucleotide sequence of an oligonucleotide is provided. In certain embodiments, the method comprises: a) inputting the nucleotide sequence of an oligonucleotide; b) executing an algorithm that provides the predicted molecular formulas of fragments of the oligonucleotide; c) comparing the predicted m/z values of the predicted molecular formulas to experimentally-obtained m/z values obtained by analysis of the oligonucleotide by tandem mass spectrometry to determine if the predicted masses correspond with the experimentally-obtained masses. The method may be used, for example, to confirm the identity of an oligonucleotide after it is synthesized.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: July 16, 2013
    Assignee: Agilent Technologies, Inc.
    Inventors: Zoltan Timar, Gergo Hegedus
  • METHOD OF OLIGONUCLEOTIDE SEQUENCING BY MASS SPECTROMETRY
    Publication number: 20120100623
    Abstract: A computer-implemented method for confirming the nucleotide sequence of an oligonucleotide is provided. In certain embodiments, the method comprises: a) inputting the nucleotide sequence of an oligonucleotide; b) executing an algorithm that provides the predicted molecular formulas of fragments of the oligonucleotide; c) comparing the predicted m/z values of the predicted molecular formulas to experimentally-obtained m/z values obtained by analysis of the oligonucleotide by tandem mass spectrometry to determine if the predicted masses correspond with the experimentally-obtained masses. The method may be used, for example, to confirm the identity of a. oligonucleotide after it is synthesized, i.e., to confirm that it has the expected sequence.
    Type: Application
    Filed: April 25, 2011
    Publication date: April 26, 2012
    Inventors: Zoltan Timar, Gergo Hegedus