Patents by Inventor Gerhard Barnickel

Gerhard Barnickel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-amino-quinazolines
    Patent number: 7829566
    Abstract: Quinazolines of the formula I in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent Claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: November 9, 2010
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark R. Player, Edward Jaeger, Richard Soll
  • 4-amino-quinazolines
    Patent number: 7547702
    Abstract: Quinazolines of the formula (I) in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein 1bIX antagonists.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: June 16, 2009
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Werner Mederski, Maria Devant, legal representative, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark R. Player, Edward Jaegar, Richard Soll, Ralf Devant
  • Squaric Acid Derivatives as Protein Kinase Inhibitors
    Publication number: 20080312244
    Abstract: Compounds of the formula I, in which R, X, R1, R2, R3, R4 and R5 have the meanings indicated in Claim 1, are inhibitors of CHK1 CHK2 and SGK kinases and can be employed, inter alia, for the treatment of cancer.
    Type: Application
    Filed: June 30, 2006
    Publication date: December 18, 2008
    Inventors: Werner Mederski, Ulrich Emde, Gerhard Barnickel, Frank Zenke, Hartmut Greiner, Frank Stieber
  • Squaric Acid Derivatives II
    Publication number: 20080234266
    Abstract: Compounds of the formula (I), in which R, X, X? and R2, R2?, R2?, R3?, R2?? and R7 have the meanings indicated in claim 1, are inhibitors of CHK1 CHK2 and SGK kinases and can be employed, inter alia, for the treatment of cancer.
    Type: Application
    Filed: June 30, 2006
    Publication date: September 25, 2008
    Inventors: Werner Mederski, Ulrich Emde, Gerhard Barnickel, Frank Zenke, Hartmut Greiner, Frank Stieber
  • Use Of Thienopyrimidines
    Publication number: 20080045529
    Abstract: The invention relates to compounds of formula (I), wherein R1, R2, R3, R4, X and n have the meanings cited in claim (1). Said compounds are inhibitors of tyrosinkinases, especially TIE-2, and Raf-Kinases and can be used, for example, in the treatment of tumours.
    Type: Application
    Filed: October 14, 2004
    Publication date: February 21, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Hans-Michael Eggenweiler, Alfred Jonczyk, Gerhard Barnickel, Wilfried Rautenberg, Helga Drosdat, Arne Sutter
  • 4-Amino-quinazolines
    Publication number: 20070293667
    Abstract: Quinazolines of the formula I in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent Claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Application
    Filed: December 14, 2005
    Publication date: December 20, 2007
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark Player, Edward Jaeger, Richard Soll
  • INHIBITORS OF POLYQ-AGGREGATION
    Publication number: 20070259887
    Abstract: Compounds of formula I, wherein R1, R2, R3, R4 and R5 have the meanings as given in claim 1, and their pharmaceutically tolerable derivatives, solvates and stereoisomers and their use for the preparation of a pharmaceutical for inhibiting the formation of polyQ-aggregation.
    Type: Application
    Filed: June 8, 2007
    Publication date: November 8, 2007
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: HENNING BOTTCHER, Christian Herhaus, Gerhard Barnickel, Erich Wanker, Volker Heiser, Hans Lehrach, Wolfgang Broecker, Ilona Dunkel
  • Quinazolinones
    Patent number: 7060706
    Abstract: Quinazolinones of formula (I) in which R, R1, R2, R3, R4, Y, n and m have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: June 13, 2006
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, Guido Melzer, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark Player, Richard Soll
  • 4-Amino-quinazolines
    Publication number: 20060019974
    Abstract: Quinazolines of the formula (I) in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Application
    Filed: September 17, 2001
    Publication date: January 26, 2006
    Inventors: Werner Mederski, Ralf Devant, Maria Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark Player, Edward Jaeger, Richard Soll
  • Quinazolinones
    Patent number: 6890930
    Abstract: Quinazolinones of formula (I) in which R, R1, R2, R3, R4, Y, Z, and m have the meaning indicated in patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: May 10, 2005
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Werner Mederski, Maria Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, Guido Melzer, Bertram Cezane, Dalijit Dhanoa, Bao-Ping Zhoa, James Rinker, Mark Player, Richard Soll, Ralf Devant
  • Method for determining pharmaceutically active substances
    Publication number: 20040093170
    Abstract: The present invention relates to a method for determining pharmaceutically active substances with the aid of test series, in which the action of a large number of different substances on one or more biological targets is tested and a hit list of those substances which actually or apparently have shown a pharmaceutical action on at least one biological target is prepared, whereupon a selection is made from the hits for more detailed investigations of pharmaceutical activity and/or applicability.
    Type: Application
    Filed: August 19, 2003
    Publication date: May 13, 2004
    Inventors: Soheila Anzali, Gerhard Barnickel, Bertram Cezanne, Michael Krug, Joachim Marz
  • 4-amino-quinazolines
    Publication number: 20040044204
    Abstract: Quinazolines of the formula I, in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Application
    Filed: March 20, 2003
    Publication date: March 4, 2004
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark R Player, Edward Jaeger, Richard Soll
  • Sulphonyloxazolamines as therapeutic active ingredients
    Patent number: 6441013
    Abstract: The present invention relates to sulphonylexazolamines of general formula (I), wherein R1, R2 represent independently from each other H, A, —(CH2)n—Ar or alkenyl with 2-6 C atoms, R1 and R2 together also represent a mononuclear saturated heterocycle with 1-2 N, O and/or S atoms, Z is H, A, CF3, NO2, Hal, OH, OA, NH2, NHA or NH2. A represents alkyl with 1-6 C atoms, Ar is Z-monosubstituted or Z-disubstituted phenyl, Hal is F, Cl, Br, or L n is 1 or 2 of the physiologically acceptable salts or solvates thereof. Said sulphonyloxazolamines are used as therapeutic active ingredients. The invention also relates to the use of sulphonyloxazolamines as therapeutic active ingredients and/or to the production of pharmaceutical preparations to combat diseases of the central nervous system. The invention further relates to a pharmaceutical preparation and the production thereof.
    Type: Grant
    Filed: June 14, 2001
    Date of Patent: August 27, 2002
    Assignee: Merck Patent GmbH
    Inventors: Hartmut Greiner, Gerd Bartoszyk, Henning Böttcher, Gerhard Barnickel, Bertram Cezanne