Patents by Inventor Gerhard Cullman

Gerhard Cullman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting acid-resistant microorganisms in the stool
    Patent number: 7736859
    Abstract: The invention relates to a method for detecting an infection of a mammal with an acid-resistant microorganism, wherein (a) a stool sample of a mammal is incubated with at least two different monoclonal antibodies, fragments or derivatives thereof or aptamers under conditions allowing a complex formation of antigens of the acid-resistant microorganism with antibodies, fragments or derivatives thereof or the aptamers, and wherein (aa) the first monoclonal antibody or the fragment or the derivative thereof or the first aptamer specifically binds an epitope of the first antigen, which shows at least with some mammals a structure after the intestinal passage that corresponds to the native structure or the structure which a mammal produces antibodies against after being infected or immunised with the acid-resistant microorganism or an extract or lysate thereof or a protein therefrom or a fragment thereof or a synthetic peptide; (ab) the second monoclonal antibody or the fragment or the derivative thereof or the sec
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: June 15, 2010
    Assignee: Oxoid (ELY) Limited
    Inventors: Christian Reiter, Gerhard Cullman, Ulrike Friedrichs, Petra Heppner, Meret Lakner, Achim Ringeis
  • Method for detecting acid-resistant microorganisms in the stool
    Publication number: 20070009975
    Abstract: The invention relates to a method for detecting an infection of a mammal with an acid-resistant microorganism, wherein (a) a stool sample of a mammal is incubated with at least two different monoclonal antibodies, fragments or derivatives thereof or aptamers under conditions allowing a complex formation of antigens of the acid-resistant microorganism with antibodies, fragments or derivatives thereof or the aptamers, and wherein (aa) the first monoclonal antibody or the fragment or the derivative thereof or the first aptamer specifically binds an epitope of the first antigen, which shows at least with some mammals a structure after the intestinal passage that corresponds to the native structure or the structure which a mammal produces antibodies against after being infected or immunised with the acid-resistant microorganism or an extract or lysate thereof or a protein therefrom or a fragment thereof or a synthetic peptide; (ab) the second monoclonal antibody or the fragment or the derivative thereof or the sec
    Type: Application
    Filed: August 31, 2006
    Publication date: January 11, 2007
    Applicant: DakoCytomation Denmark A/S
    Inventors: Christian Reiter, Gerhard Cullman, Ulrike Friedrichs, Petra Heppner, Meret Lakner, Achim Ringeis
  • Immuno-chromatographic rapid assay in order to detect acid-resistant microorganisms in the stool
    Patent number: 7129053
    Abstract: The invention relates to a method for detecting an infection of a mammal with an acid-resistant microorganism comprising the following steps: (a) provision of an immunochromatographic test with a sample application area for the application of a stool sample of the mammal with an antigen and application of the stool sample, (b) incubation of the stool sample using (i) a first receptor under conditions permitting a complex formation of the antigen from the acid resistant microorganism with the receptor; or (ii) at least two different first receptors under conditions permitting a complex formation of the antigen from the acid-resistant microorganism with the at least two first receptors and wherein the first receptor according to (i) or the first receptors according to (ii) specifically bind(s) an antigen which shows, at least with some mammals, a structure after passage through the intestine that corresponds to the native structure or the structure against which a mammal produces antibodies against after being
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: October 31, 2006
    Assignee: Dakocytomation Denmark A/S
    Inventors: Christian Reiter, Gerhard Cullman, Meret Lakner, Andreas Trüe, Sonja Dehnert, Georg Schwartz
  • Method for detecting acid-resistant microorganisms in the stool
    Patent number: 7122320
    Abstract: The invention relates to a method for detecting an infection of a mammal with an acid-resistant microorganism, wherein (a) a stool sample of a mammal is incubated with at least two different monoclonal antibodies, fragments or derivatives thereof or aptamers under conditions allowing a complex formation of antigens of the acid-resistant microorganism with antibodies, fragments or derivatives thereof or the aptamers, and wherein (aa) the first monoclonal antibody or the fragment or the derivative thereof or the first aptamer specifically binds an epitope of the first antigen, which shows at least with some mammals a structure after the intestinal passage that corresponds to the native structure or the structure which a mammal produces antibodies against after being infected or immunised with the acid-resistant microorganism or an extract or lysate thereof or a protein therefrom or a fragment thereof or a synthetic peptide; (ab) the second monoclonal antibody or the fragment or the derivative thereof or the sec
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: October 17, 2006
    Assignee: Gesellschaft zur Optimierung von Forschung und Entwicklung mbH
    Inventors: Christian Reiter, Gerhard Cullman, Ulrike Friedrichs, Petra Heppner, Meret Lakner, Achim Ringeis