Patents by Inventor Gerhard Frey

Gerhard Frey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7785855
    Abstract: The invention relates to nucleic acids encoding polypeptides having amylase activity, and methods for making and using them. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides encoded by the nucleic acids of this invention.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: August 31, 2010
    Assignee: Syngenta Participations AG
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Patent number: 7781201
    Abstract: This invention relates generally to polypeptides and peptides having an amylase activity, e.g., enzymes, polynucleotides encoding the enzymes, the use of such polypeptides and peptides. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides having amylase activity of the invention.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: August 24, 2010
    Assignee: Syngenta Participations AG
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Publication number: 20100209995
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars.
    Type: Application
    Filed: February 1, 2010
    Publication date: August 19, 2010
    Applicant: VERENIUM CORPORATION
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl Miller, Martin Kazaoka, Eric Mathur, Jay Short
  • Patent number: 7759093
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: July 20, 2010
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Kevin Gray, Janne S. Kerovuo, Malgorzata Slupska, Nelson Barton, Eileen O'Donoghue, Carl Miller
  • Publication number: 20100158679
    Abstract: A pair of one piece cast impellers having radially extending curved and twisted three dimensional blades and being in a compressor housing which is connected to a drive motor and the impellers being mounted onto a motor drive shaft by jamming or press fitting the impellers on the shaft to provide a two stage radial compressor wherein the drive motor (5), a drive shaft (14) on which there a arranged two impellers (10, 12) there is envisaged that the drive motor (5) is a fast-running asynchronous motor with a speed in excess of 10,000 rpm and a power of around 5 to 10 kW.
    Type: Application
    Filed: July 19, 2006
    Publication date: June 24, 2010
    Inventors: Norbert Aust, Gerhard Frey, Jürgen Fischer
  • Publication number: 20100136113
    Abstract: This invention relates to phytases, polynucleotides encoding them, uses of the polynucleotides and polypeptides of the invention, as well as the production and isolation of such polynucleotides and polypeptides. In particular, the invention provides polypeptides having phytase activity under high temperature conditions, and phytases that retain activity after exposure to high temperatures. The phytases of the invention can be thermotolerant and/or thermostable at low temperatures, in addition to higher temperatures. The phytases of the invention can be used in foodstuffs to improve the feeding value of phytate rich ingredients. The phytases of the invention can be formulated as foods or feeds or supplements for either to, e.g., aid in the digestion of phytate. The foods or feeds of the invention can be in the form of pellets, liquids, powders and the like.
    Type: Application
    Filed: September 21, 2007
    Publication date: June 3, 2010
    Applicant: VERENIUM CORPORATION
    Inventors: Brian Steer, Mark Dycaico, Katie A. Kline, Axel Trefzer, Thomas Todaro, Arne Solbak, Fatima El-Farrah, Alberto Alvarado, Gerhard Frey
  • Publication number: 20100138945
    Abstract: The present invention relates to novel chimeric, humanized or CDR-grafted anti-IL-6 antibodies, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Application
    Filed: November 13, 2009
    Publication date: June 3, 2010
    Applicant: BIOATLA, LLC
    Inventors: Gerhard Frey, Hwai Wen Chang, Jay Short
  • Publication number: 20100104553
    Abstract: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic antibodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.
    Type: Application
    Filed: September 14, 2007
    Publication date: April 29, 2010
    Inventors: Gerhard FREY, Bruce E. Kimmel, Abraham Anderson
  • Publication number: 20100047392
    Abstract: The invention relates to alpha amylases and to polynucleotides and polypeptides encoding the alpha amylases. In addition, methods of using the alpha amylases are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and at increased temperatures.
    Type: Application
    Filed: September 25, 2009
    Publication date: February 25, 2010
    Applicant: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Patent number: 7666633
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases, and methods of making and using them. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: February 23, 2010
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl Miller, Martin Kazaoka, Jay M. Short, Eric J. Mathur
  • Patent number: 7659102
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for malting and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into 10 sugars.
    Type: Grant
    Filed: March 24, 2003
    Date of Patent: February 9, 2010
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl A. Miller, Martin Kazaoka, Eric J. Mathur, Jay M. Short
  • Publication number: 20090285813
    Abstract: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic anti-bodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.
    Type: Application
    Filed: June 18, 2009
    Publication date: November 19, 2009
    Inventors: GERHARD FREY, BRUCE E. KIMMEL, ABRAHAM ANDERSON
  • Patent number: 7560126
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars.
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: July 14, 2009
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska, Nelson R. Barton, Eileen O'Donoghue, Eric J. Mathur, Jay M. Short
  • Publication number: 20080274155
    Abstract: The invention provides chimeric cannulae polypeptides and nanotubules and methods for making and using them. In one aspect, the invention provides compositions and methods for the identification, separation or synthesis of proteins or ligands. In one aspect, the invention provides compositions and methods for making and using nanotubules. In one aspect, the invention provides compositions and methods for the selection and purification of chiral compositions from racemic mixtures. In one aspect, the chimeric proteins and polymers (e.g., nanotubules, tubules, bundles, balls, fibers, filaments, sheets, threads, textiles) of the invention comprise a detectable moiety, e.g., a fluorescent protein. In one aspect, the invention provides a flame retardant or heat resistant device comprising a sheeting, a covering, a coating or an adhesive comprising a chimeric protein of the invention.
    Type: Application
    Filed: March 24, 2005
    Publication date: November 6, 2008
    Applicant: Verenium Corporation
    Inventors: Nelson R. Barton, Eileen O'Donoghue, Ryan Short, Gerhard Frey, David Weiner, Dan E. Robertson, Steven Briggs, Paul Zorner
  • Patent number: 7407677
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and increased temperature.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: August 5, 2008
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Publication number: 20080047037
    Abstract: The invention relates to nucleic acids encoding polypeptides having amylase activity, and methods for making and using them. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides encoded by the nucleic acids of this invention.
    Type: Application
    Filed: January 9, 2007
    Publication date: February 21, 2008
    Applicant: Diversa Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay Short, Eric Mathur, Kevin Gray, Janne Kerovuo, Malgorzata Slupska
  • Publication number: 20080032378
    Abstract: This invention relates generally to polypeptides and peptides having an amylase activity, e.g., enzymes, polynucleotides encoding the enzymes, the use of such polypeptides and peptides. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides having amylase activity of the invention.
    Type: Application
    Filed: January 9, 2007
    Publication date: February 7, 2008
    Applicant: Diversa Corporation
    Inventors: Walter CALLEN, Toby Richardson, Gerhard Frey, Jay Short, Eric Mathur, Kevin Gray, Janne Kerovuo, Malgorzata Slupska
  • Patent number: 7323336
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: January 29, 2008
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl Miller, Martin Kazaoka, Jay M. Short, Eric J. Mathur
  • Publication number: 20080021623
    Abstract: A brake control system for a vehicle, in particular a commercial vehicle, includes a service brake for braking the wheels of the vehicle. To increase operating safety, the service brake is equipped with an electronically actuatable brake unit for each wheel for actuating the brake of the respective wheel. Two redundantly connected central control devices are connected via control lines to the brake units so as to actuate the brake units independently of one another.
    Type: Application
    Filed: February 23, 2005
    Publication date: January 24, 2008
    Applicant: DaimlerChrysler AG
    Inventors: Gerhard Frey, Ottmar Gehring, Harro Heilmann, Andreas Schwarzhaupt, Gernot Spiegelberg, Armin Sulzmann
  • Publication number: 20070260382
    Abstract: A control system having an electronically controllable drive train. A coordination level is assigned to a system control device in which set point values are generated from state variables of the vehicle and from driver's wishes and actuation signals for actuating actuators are generated therefrom. An execution level is subordinate to the coordination level and has actuators for executing the actuation signal. An axle electronic module activates at least one brake actuator assigned to the vehicle axle, and is arranged in the region of the vehicle axle. The axle electronic module is connected to the coordination level in order to transmit set point values, and is designed to determine actuation signals from the set point values in order to control the respective axle actuator. The axle electronic module is connected to a controllable differential lock in order to transmit the actuation signals.
    Type: Application
    Filed: October 26, 2004
    Publication date: November 8, 2007
    Applicant: Daimlerchrysler AG
    Inventors: Gerhard Frey, Harro Heilmann, Klaus-Dieter Holloh, Eilert Martens, Christian Quinger, Andreas Schwarzhaupt, Gernot Spiegelberg, Armin Sulzmann