Patents by Inventor Gerhard Grundler

Gerhard Grundler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7531540
    Abstract: The compounds of formula I in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: May 12, 2009
    Assignee: Nycomed GmbH
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • Publication number: 20070129373
    Abstract: The compounds of formula I in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: December 29, 2006
    Publication date: June 7, 2007
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Sterk
  • Patent number: 7179810
    Abstract: The compounds of formula I in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: February 20, 2007
    Assignee: Altana Pharma AG
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • Publication number: 20060148796
    Abstract: The present invention relates to 6-substituted imidazopyrazines of formula 1 in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
    Type: Application
    Filed: February 16, 2004
    Publication date: July 6, 2006
    Inventors: Peter Zimmermann, Wilm Buhr, M. Chiesa, Andreas Palmer, Christof Brehm, Gerhard Grundler, Joerg Senn-Bilfinger, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer
  • Patent number: 7022696
    Abstract: The compounds of formula I in which R1, R2, R3, A, X, s and R9 have the meanings as given in the description are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: April 4, 2006
    Assignee: Altana Pharma AG
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • Publication number: 20050234062
    Abstract: The compounds of formula I in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: June 3, 2005
    Publication date: October 20, 2005
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Sterk
  • Patent number: 6953853
    Abstract: The compounds of a formula I, in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: October 11, 2005
    Assignee: Altana Pharma AG
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • Patent number: 6818651
    Abstract: 3,4-Dihydroisoquinoline and isoquinoline compounds of formula I, in which Ar represents a phenyl raidcal of the formulae IIa, IIb or IIc are novel effective PDE7 inhibitors.
    Type: Grant
    Filed: August 21, 2003
    Date of Patent: November 16, 2004
    Assignee: Altana Pharma AG
    Inventors: Steffen Weinbrenner, Beate Schmidt, Gerhard Grundler, Josef Stadlwieser, Armin Hatzelmann, Geert Jan Sterk
  • Patent number: 6818642
    Abstract: Benzylaminopyrimidine compounds of a certain general formula I, in which the substituents and symbols are as defined in the description, are suitable for controlling Helicobacter bacteria.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: November 16, 2004
    Assignee: Altana Pharma AG
    Inventor: Gerhard Grundler
  • Publication number: 20040158066
    Abstract: Pyridylmethylaminopyrimidine compounds of a certain general formula I, in which the substituents and symbols are as defined in the description, are suitable for controlling Helicobacter bacteria.
    Type: Application
    Filed: April 7, 2004
    Publication date: August 12, 2004
    Inventors: Vittoria Chiesa, Gerhard Grundler
  • Publication number: 20040152714
    Abstract: Benzylaminopyrimidine compounds of a certain general formula I, in which the substituents and symbols are as defined in the description, are suitable for controlling Helicobacter bacteria.
    Type: Application
    Filed: March 23, 2004
    Publication date: August 5, 2004
    Inventor: Gerhard Grundler
  • Publication number: 20040132721
    Abstract: The compounds of formula I, in which R1, R2, R3, A, X, s and R9 have the meanings as given in the description are novel effecfive PDE4 inhibitors.
    Type: Application
    Filed: October 23, 2003
    Publication date: July 8, 2004
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • Publication number: 20040067946
    Abstract: The compounds of a formula I, in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: August 13, 2003
    Publication date: April 8, 2004
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • Patent number: 6479514
    Abstract: Compounds of formula (I) in which the substituents and symbols have the meanings indicated in the description, are suitable for the control of Helicobacter bacteria.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: November 12, 2002
    Assignee: Altana Pharma AG
    Inventors: Peter Zimmerman, Gerhard Grundler
  • Patent number: 6395732
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, and R3 are hydrogen, 1-4C-alkyl, or halogen; R4, R5, R6, and R9 are hydrogen or 1-4C-alkyl; R7 and R8 are hydrogen, 1-4C-alkyl, 1-4C-alkoxy, or halogen; A is 1-7C-alkylene, 2-7C-alkenylene, 3-7C-cycloalkylene, or phenylene; G is hydrogen, hydroxyl, 1-7C-alkyl, 1-4C-alkyl substituted by fluorine, 2-7C-alkenyl, 3-7C-cycloalkyl, a mono- or di-1-4C-alkylcarbamoyl or -thiocarbamoyl, N-1-4C-alkyl-N′-cyanoamidino, 1-N-1-4C-alkylamino-2-nitroethylene, N-2-propynyl-N′-cyanoamidino, aminosulfonylamidino, —N(R10)R11, the part of the compound of formula (I) bonded to A, glucopyranoside, or a cyclic system or bicyclic system which is optionally substituted by R12 and R13; X is oxygen, N-1-4C-alkyl, NH, or S; Y is oxygen, N-1-4C-alkyl, NH, S, 1,4-piperazinylene, or 1,4-piperidinylene; Z is oxygen, N-1-4C-alkyl, NH, S, or CO; m is from 1 to 7; n is from 0 to 4; t is 0, 1, or 2; and u is 0 or 1, and their salts suitable for controllin
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: May 28, 2002
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Peter Zimmermann, Gerhard Grundler
  • Patent number: 6197783
    Abstract: Tetrahydropyrido compounds of formula (I) in which the substituents have the meanings mentioned in the description, are suitable for the prevention or treatment of gastrointestinal diseases.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: March 6, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Jörg Senn-Bilfinger, Gerhard Grundler
  • Patent number: 6162809
    Abstract: Pyridinylthiomethyl- and pyrimidinylthiomethyl-pyridines and their pharmacologically-acceptable compositions are useful for controlling Helicobacter bacteria and for treating those afflicted with diseases based on Helicobacter bacteria.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: December 19, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Bernhard Kohl, Gerhard Grundler, Jorg Senn-Bilfinger
  • Patent number: 6124313
    Abstract: Imidazopyridine-azolidinones are useful for treating or preventing amenable gastro-intestinal ailments.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: September 26, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Gerhard Grundler, Jorg Senn-Bilfinger, Ulrich Thibaut, Georg Rainer
  • Patent number: 6107312
    Abstract: Thiopyridines of formula (I) ##STR1## in which the substituents and symbols are as defined in the specification are suitable for use in controlling Helicobacter bacteria. They are compounded into medicament compositions and administered to subjects afflicted with a disease based on Helicobacter bacteria.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: August 22, 2000
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Bernhard Kohl, Gerhard Grundler, Jorg Senn-Bilfinger
  • Patent number: 6096758
    Abstract: The invention relates to certain substituted imidazo[1,2-a]pyridines useful in the treatment of gastro-intestinal disorders.
    Type: Grant
    Filed: July 24, 1998
    Date of Patent: August 1, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Gerhard Grundler, Jorg Senn-Bilfinger