Patents by Inventor Gerhard Guthorlein

Gerhard Guthorlein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating excessive fibrinolysis with synthetically modified trypsin inhibitors
    Patent number: 3992529
    Abstract: Method of treating excessive fibrinolysis with a modified trypsin-callicrein inhibitor wherein the five carboxyl groups present in the unmodified material are amidated by--(R)(R).sub.X W groups,wherein R is prolyl or ##EQU1## X is an integer from 1 to 10, Y is hydrogen, alkyl, or substituted alkyl and W is --OH, --NH.sub.2, --NHC.sub.2 H.sub.5, --OCH.sub.3, or --OC.sub.2 H.sub.5.
    Type: Grant
    Filed: December 1, 1975
    Date of Patent: November 16, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wolfgang Konig, Oswald Zwisler, Gerhard Guthorlein
  • Synthetically modified trypsin inhibitors and process for preparing them
    Patent number: 3953417
    Abstract: Modified trypsin-callicrein inhibitor wherein the five carboxyl groups present in the unmodified material are amidated by--(R)(R).sub.X W groups,Wherein R is prolyl or ##EQU1## X is an integer from 1 to 10, Y is hydrogen, alkyl, or substituted alkyl and W is --OH, --NH.sub.2, --NHC.sub.2 H.sub.5, --OCH.sub.3, or --OC.sub.2 H.sub.5. Method for making trypsin-callicrein inhibitor so modified by amidation.
    Type: Grant
    Filed: September 4, 1974
    Date of Patent: April 27, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wolfgang Konig, Oswald Zwisler, Gerhard Guthorlein