Patents by Inventor Gerhard Jahne

Gerhard Jahne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of polycyclic 2-aminothiazole systems for the treatment of obesity
    Patent number: 6476059
    Abstract: The invention relates to the use of polycyclic 2-aminothiazole systems and their physiologically tolerated salts and physiologically functional derivatives for the treatment of obesity. The treatment involves administration of a compound of formula I, in which the radicals have the stated meanings, and of their physiologically tolerated salts and physiologically functional derivatives.
    Type: Grant
    Filed: February 10, 2000
    Date of Patent: November 5, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
  • Substituted benzimidazoles
    Patent number: 6358978
    Abstract: Compounds of formula I are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in whose course an increased activity of NF&kgr;B is involved.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: March 19, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Olaf Ritzeler, Hans Ulrich Stilz, Bernhard Neises, William Jerome Bock, Jr., Armin Walser, Gary A. Flynn, Jörg Habermann, Gerhard Jähne
  • Use of polycyclic thiazole systems for the treatment of obesity
    Patent number: 6329407
    Abstract: The invention relates to the use of polycyclic thiazole systems and their physiologically tolerated salts and physiologically functional derivatives for the treatment of obesity. The treatment involves administration of a compound of formula I, in which the radicals have the stated meanings, and of their physiologically tolerated salts and physiologically functional derivatives.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: December 11, 2001
    Assignee: AventisPharma Deutschland GmbH
    Inventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
  • Polycyclic thiazol-2-ylidene amines, processes for their preparation and their use as medicaments
    Patent number: 6288094
    Abstract: The invention relates to polycyclic thiazolidin-2-ylidene amines and their physiologically tolerated salts and physiologically functional derivatives. Polycyclic thiazolidin-2-ylidene amines of the formula I, in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation are described. The compounds are suitable, for example as anorectics and in the treatment or prophylaxis of type II diabetes.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: September 11, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
  • Polycyclic thiazol-2-ylidene amines, processes for their preparation and their use as medicaments
    Patent number: 6288093
    Abstract: The invention relates to polycyclic thiazolidin-2-ylidene amines and their physiologically tolerated salts and physiologically functional derivatives. Polycyclic thiazolidin-2-ylidene amines of the formula I, in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation are described. The compounds are suitable, for example as anorectics and in the treatment or prophylaxis of type II diabetes.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: September 11, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
  • Polycyclic thiazol-2-ylidene amines, processes for their preparation and their use as medicaments
    Publication number: 20010011096
    Abstract: The invention relates to polycyclic thiazolidin-2-ylidene amines and their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: January 31, 2001
    Publication date: August 2, 2001
    Inventors: Gerhard Jahne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
  • Polycyclic 2- aminothiazole systems, processes for their preparation and pharmaceuticals comprising these compounds
    Patent number: 6251922
    Abstract: The invention relates to polycyclic 2-aminothiazole systems and their physiologically tolerated salts and physiologically functional derivatives. The polycyclic 2-aminothiazole systems are according to formula I, in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation are described. The compounds are suitable, for example, as anorectics.
    Type: Grant
    Filed: February 10, 2000
    Date of Patent: June 26, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
  • Polycyclic thiazol-2-ylidene amines, processes for their preparation and their use as medicaments
    Patent number: 6207689
    Abstract: The invention relates to polycyclic thiazolidin-2-ylidene amines and their physiologically tolerated salts and physiologically functional derivatives. Polycyclic thiazolidin-2-ylidene amines of the formula I, in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation are described. The compounds are suitable, for example as anorectics and in the treatment or prophylaxis of type II diabetes.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: March 27, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
  • Polycyclic thiazole systems, processes for their preparation and pharmaceuticals comprising these compounds
    Patent number: 6187801
    Abstract: The invention relates to polycyclic thiazole systems and their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I, in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation are described. The compounds are suitable, for example, as anorectics.
    Type: Grant
    Filed: February 10, 2000
    Date of Patent: February 13, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
  • Compounds for treating disorders of lipid metabolism and their preparation
    Patent number: 5939424
    Abstract: The invention relates to 4-Amino-2-ureidopyrimidine-5-carboxamides of the formula I ##STR1## in which R.sup.1 is H or (C.sub.1 -C.sub.8)-alkyl, where one or more H can be replaced by F; R.sup.2 is selected from the group consisting of F, Cl, Br, H, -O-(C.sub.1 -C.sub.8)-alkyl, and -S-(C.sub.1 -C.sub.8)-alkyl, where the alkyl groups have one or more H replaced by F; R.sup.3 is -O-(C.sub.1 -C.sub.8)-alkyl or -S-(C.sub.1 -C.sub.8)-alkyl, where the alkyl groups have one or more H replaced by F; or R.sup.2 and R.sup.3 together form -O-(C.sub.1 -C.sub.5)-alkylene-O-, where the alkylene portion has one or more H replaced by F; and their physiologically tolerable salts. The invention further provides processes for preparing the compounds of formula I. The compounds are suitable for the treatment of disorders of lipid metabolism.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: August 17, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Georg Boger, Axel Hoffmann, Gerhard Jahne, Norbert Krass, Hans-Ludwig Schafer
  • Process for the preparation of 5-substituted cytosines and other 4,5-disubstituted pyrimidin-2(1H)-ones, and intermediates arising in the course of this
    Patent number: 5359067
    Abstract: Process for the preparation of 5-substituted cytosines and other 4,5-disubstituted pyrimidin-2(1H)-ones, and intermediates arising in the course of thisThe process for the preparation of compounds of the formula I, ##STR1## wherein compounds of the formula II ##STR2## are converted into an azole derivative of the formula III or an azine derivative of the formula IV ##STR3## which can subsequently be converted into a compound of the formula I using a nucleophile XH.
    Type: Grant
    Filed: November 19, 1992
    Date of Patent: October 25, 1994
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Gerhard Jahne
  • Process for the preparation of acylals
    Patent number: 5231221
    Abstract: Compounds of the formula ##STR1## can advantageously be prepared by reacting compounds the formula II ##STR2## in which the substituents R.sup.1 -R.sup.4 have the meanings given, with the anhydride of the formula III ##STR3## in the presence of dimethyl sulfoxide and the acid corresponding to the anhydride of the formula III.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: July 27, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Winfried Hertzsch, Gerhard Jahne
  • Process for the preparation of substituted acyclic nucleosides, and intermediates occurring therein
    Patent number: 5225550
    Abstract: It is possible, by using symmetrical formaldehyde acetals of the formula ##STR1## in which the substituents R.sup.1 -R.sup.3 have the specified meanings, advantageously to introduce the substituent ##STR2## into nitrogen-containing heterocyclic systems to form acyclic nucleoside analogs.
    Type: Grant
    Filed: June 25, 1991
    Date of Patent: July 6, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Gerhard Jahne