Patents by Inventor Gerhard Johann

Gerhard Johann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190077873
    Abstract: Provided herein are, inter alia, humanized 1E9 antibodies capable of binding CD73. The humanized antibodies are useful for the treatment of cancer. Further provided are nucleic acids encoding humanized 1E9 antibodies and methods of inhibiting cell proliferation using the humanized antibodies provided herein.
    Type: Application
    Filed: December 9, 2016
    Publication date: March 14, 2019
    Inventors: Emily Piccione Griffin, Richard A. Miller, Gerhard Johann Frey, Hwai Wen Chang
  • Publication number: 20190000944
    Abstract: Provided are compositions for use in methods for treating diseases associated with expression of mesothelin comprising administering a cell that expresses a chimeric antigen receptor (CAR) specific to mesothelin in combination with a PD-L1 inhibitor.
    Type: Application
    Filed: December 21, 2016
    Publication date: January 3, 2019
    Inventors: Jennifer Brogdon, Hwai Wen Chang, Boris Engels, Gordon James Freeman, Gerhard Johann Frey, Jennifer Marie Mataraza, Reshma Singh, Arlene Helen Sharpe
  • Publication number: 20180340025
    Abstract: Combination therapies comprising antibody molecules that specifically bind to LAG-3 are disclosed. The combination therapies can be used to treat, prevent and/or diagnose cancerous or infectious disorders.
    Type: Application
    Filed: July 28, 2016
    Publication date: November 29, 2018
    Applicants: Novartis AG, Immutep S.A.S.
    Inventors: Glenn Dranoff, Frédéric Triebel, Chrystelle Brignone, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Publication number: 20180222982
    Abstract: Combination therapies comprising antibody molecules that specifically bind to PD-1 disclosed. The combination therapies can be used to treat or prevent cancerous or infectious conditions and disorders.
    Type: Application
    Filed: July 28, 2016
    Publication date: August 9, 2018
    Inventors: Glenn Dranoff, Gordon James Freeman, Arlene Helen Sharpe, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Publication number: 20180186882
    Abstract: Antibody molecules that specifically bind to PD-L1 are disclosed. Combination therapies comprising the anti-PD-L1 antibody molecules are also disclosed. The anti-PD-L1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Application
    Filed: February 20, 2018
    Publication date: July 5, 2018
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Gerhard Johann Frey, Hwai Wen Chang, Jennifer Marie Mataraza, Glenn Dranoff
  • Publication number: 20180155427
    Abstract: Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Application
    Filed: October 6, 2017
    Publication date: June 7, 2018
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Patent number: 9988452
    Abstract: Antibody molecules that specifically bind to PD-L1 are disclosed. Combination therapies comprising the anti-PD-L1 antibody molecules are also disclosed. The anti-PD-L1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: June 5, 2018
    Assignees: Novartis AG, DANA-FARBER CANCER INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Gerhard Johann Frey, Hwai Wen Chang, Jennifer Marie Mataraza, Glenn Dranoff
  • Publication number: 20180086830
    Abstract: Antibody molecules that specifically bind to LAG-3 are disclosed. The anti-LAG-3 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious disorders.
    Type: Application
    Filed: December 1, 2017
    Publication date: March 29, 2018
    Inventors: Frédéric Triebel, Chrystelle Brignone, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Patent number: 9908936
    Abstract: Antibody molecules that specifically bind to LAG-3 are disclosed. The anti-LAG-3 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious disorders.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: March 6, 2018
    Assignees: Novartis AG, Immutep S.A.S.
    Inventors: Frédéric Triebel, Chrystelle Brignone, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Patent number: 9815898
    Abstract: Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: November 14, 2017
    Assignees: Novartis AG, PRESIDENT AND FELLOWS OF HARVARD COLLEGE, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Publication number: 20170258087
    Abstract: Herbicidal oil dispersions comprising (a) desmedipham and/or phenmedipham, ethofumesate and lenacil, (b) one or more surfactants, c) one or more compounds which as far as possible are polar but at the same time are water-insoluble or have a solubility in water of up to 5 g/l, from the group of fully esterified organic phosphates and fully esterified phosphonates, as solvents, d) optionally further organic solvents, e) optionally further, customary formulating auxiliaries, f) optionally water are stable formulations and are suitable for controlling weeds, particularly for selective control in beet crops.
    Type: Application
    Filed: May 31, 2017
    Publication date: September 14, 2017
    Inventors: Gerhard JOHANN, Udo BICKERS, Mandy DENNER, Rainer BUCKPESCH, Frank SIXL
  • Patent number: 9750251
    Abstract: Herbicidal oil dispersions comprising (a) desmedipham and/or phenmedipham, ethofumesate and lenacil, (b) one or more surfactants, c) one or more compounds which as far as possible are polar but at the same time are water-insoluble or have a solubility in water of up to 5 g/l, from the group of fully esterified organic phosphates and fully esterified phosphonates, as solvents, d) optionally further organic solvents, e) optionally further, customary formulating auxiliaries, f) optionally water are stable formulations and are suitable for controlling weeds, particularly for selective control in beet crops.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: September 5, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Gerhard Johann, Udo Bickers, Mandy Denner, Rainer Buckpesch, Frank Sixl
  • Publication number: 20170247456
    Abstract: Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Application
    Filed: May 15, 2017
    Publication date: August 31, 2017
    Applicants: Novartis AG, PRESIDENT AND FELLOWS OF HARVARD COLLEGE, DANA-FARBER CANCER INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Publication number: 20170210804
    Abstract: Antibody molecules that specifically bind to LAG-3 are disclosed. The anti-LAG-3 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious disorders.
    Type: Application
    Filed: March 24, 2017
    Publication date: July 27, 2017
    Inventors: Frédéric Triebel, Chrystelle Brignone, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Patent number: 9686994
    Abstract: The present invention relates to the use of the ALS inhibitor herbicides for controlling unwanted vegetation in ALS inhibitor herbicide tolerant Beta vulgaris plants, more especially, present invention relates to the use of ALS inhibitor herbicides for control of unwanted vegetation in Beta vulgaris, preferably in sugar beet growing areas in which the Beta vulgaris, preferably sugar beet comprise mutations in the ALS gene where the tryptophan at position 569 in the encoded ALS enzyme is substituted by another amino acid (preferably by leucine), and a mutation in the ALS gene where the proline at position 188 in the encoded ALS enzyme is substituted by another amino acid (preferably by serine).
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: June 27, 2017
    Assignee: BAYER CROPSCIENCE AG
    Inventors: Ruediger Hain, Gerhard Johann
  • Patent number: 9683048
    Abstract: Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: June 20, 2017
    Assignees: NOVARTIS AG, DANA-FARBER CANCER INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Publication number: 20160298129
    Abstract: The present invention relates to an ALS inhibitor herbicide tolerant crop plants, such as allotetraploid Brassica plants, such as B. napus plants, progeny and parts thereof comprising mutations in acetolactase genes.
    Type: Application
    Filed: December 1, 2014
    Publication date: October 13, 2016
    Applicants: BAYER CROPSCIENCE NV, BAYER CROPSCIENCE LP
    Inventors: Rene RUITER, Rudiger HAIN, Gerhard JOHANN, Bernd LABER, Bart LAMBERT
  • Publication number: 20160208277
    Abstract: The present invention relates to an ALS inhibitor herbicide tolerant polyploid plants, such as B. napus or B. juncea plants, progeny and parts thereof comprising mutations in all acetolactase genes.
    Type: Application
    Filed: August 20, 2014
    Publication date: July 21, 2016
    Inventors: Rene RUITER, Rudiger HAIN, Gerhard JOHANN, Bernd LABER
  • Patent number: 9370183
    Abstract: The present invention relates to the use of the ALS inhibitor herbicides for controlling unwanted vegetation in ALS inhibitor herbicide tolerant Brassica plants, more especially, the present invention relates to the use of ALS inhibitor herbicides for control of unwanted vegetation in Brassica growing areas which Brassica plants comprise non-transgenic mutations of their endogenous acetolactate synthase (ALS) genes I and III.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: June 21, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Ruediger Hain, Gerhard Johann, Udo Bickers
  • Publication number: 20160160232
    Abstract: The present invention relates to an ALS inhibitor herbicide tolerant polyploid plants, such as B. napus or B. juncea plants, progeny and parts thereof comprising a mutation of all acetolactase genes.
    Type: Application
    Filed: July 10, 2014
    Publication date: June 9, 2016
    Inventors: Rene RUITER, Rüdiger HAIN, Gerhard JOHANN, Bernd LABER