Patents by Inventor Gerhard Keilhauer

Gerhard Keilhauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160045523
    Abstract: A pharmaceutical formulation, comprising a phosphatidylcholine product of formula (I), wherein R1 is the residue of a saturated or unsaturated fatty acid with 12-24 carbon atoms, and R2 is the residue of a saturated or unsaturated fatty acid with 12-24 carbon atoms, and wherein the phosphatidylcholine product (PC) contains the following amounts of fatty acids: 55-72 linoleic acid; 10 18 palmitic acid; 07 15 oleic acid; 02 08 linolenic acid; 02 08 stearic acid, and at least one excipient for delayed release, can be used for the improved treatment of ulcerative colitis.
    Type: Application
    Filed: March 25, 2014
    Publication date: February 18, 2016
    Inventor: Gerhard KEILHAUER
  • Patent number: 5981753
    Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
    Type: Grant
    Filed: July 15, 1997
    Date of Patent: November 9, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Keilhauer, Cynthia Romerdahl, Miguel Fernandez Brana, Xiao-Dong Qian, Peter Bousquet, Jose Maria Castellano Berlanga, Marina Moran Moset, Maria Jesus Perez De Vega
  • Patent number: 5789418
    Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: August 4, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Keilhauer, Cynthia Romerdahl, Miguel Fernandez Brana, Xiao-Dong Qian, Peter Bousquet, Jose Maria Castellano Berlanga, Marina Moran Moset, Maria Jesus Perez De Vega
  • Patent number: 5622953
    Abstract: This invention relates to 1-amino-3-phenoxy-propane-derivatives of formula 1: ##STR1## (in which A, B, R, R.sup.x, X and Z are defined as in the specification described) and methods for their preparation.These compounds may be used as modulators of multidrug resistance in cancer chemotherapy and for circumvention of resistance in the treatment of malaria.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 22, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernd Janssen, Andreas Kling, Stefan Mueller, Kurt Ritter, Rainer Schlecker, Gerhard Keilhauer, Cynthia Romerdahl, Ulrich Traugott
  • Patent number: 5616589
    Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
    Type: Grant
    Filed: August 9, 1994
    Date of Patent: April 1, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Keilhauer, Cynthia Romerdahl, Miguel F. Bra na, Xiao-Dong Qian, Peter Bousquet, Jose M.C. Berlanga, Marina M. Moset, Maria J.P. de Vega
  • Patent number: 5554622
    Abstract: Asymmetrically substituted bisnaphthalimides of the formula I ##STR1## in which A, B, D, R.sup.1, R.sup.2, m and have the meanings stated in the description, and the salts thereof with phsiologically tolerated acids, ale described. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: September 10, 1996
    Assignee: Knoll Aktiengesellschaft
    Inventors: Miguel F. Bra na, Jos e M. C. Berlanga, Marina M. Moset, Mar ia J. P erez de Vega, Gerhard Keilhauer, Xiao-Dong Qian, Cynthia Romerdahl
  • Patent number: 5552544
    Abstract: An antitumor 5-nitrobenzo[de]isoquinoline-1,3-dione of the formula I ##STR1## where n is 1 or 2, R.sup.1 and R.sup.2 are identical or different and are each hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -hydroxyalkyl, pyrrolidinyl, morpholino, piperidinyl or piperacinyl and R.sup.3 and R.sup.4 are identical or different and are each hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -acyl, C.sub.2 --C.sub.7 -alkoxycarbonyl, ureyl, aminocarbonyl or C.sub.2 -C.sub.7 -alkylaminocarbonyl, and its salts with physiologically tolerated acids, are described.
    Type: Grant
    Filed: June 4, 1990
    Date of Patent: September 3, 1996
    Inventors: Miguel F. Bra na, Jos e M. Castellano Berlanga, Marina Mor an Moset, Erich Schlick, Gerhard Keilhauer
  • Patent number: 5502032
    Abstract: Novel peptides of the formula ##STR1## in which R.sup.1, R.sup.2, X, A, R.sup.3, B, D, E, R.sup.7, M, Q, a, b and d have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
    Type: Grant
    Filed: January 5, 1994
    Date of Patent: March 26, 1996
    Assignee: BASF Aktiengesellschaft
    Inventors: Andreas Haupt, Bernd Janssen, Kurt Ritter, Dagmar Klinge, Gerhard Keilhauer, Cynthia Romerdahl, Teresa Barlozzari, Xiao-dong Qian
  • Patent number: 5180811
    Abstract: Derivatives of a tumor necrosis factor (TNF), which originate from a modification at the amino terminus of the TNF molecule are suitable for controlling diseases.
    Type: Grant
    Filed: May 13, 1988
    Date of Patent: January 19, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Thomas Doerper, Achim Moeller, Heinz Hillen, Gerhard Keilhauer, Franz Emling, Lothar Daum
  • Patent number: 5157106
    Abstract: Polypeptides which differ from lymphotoxin by the absence of amino acids at the N-terminal end of the lymphotoxin are described. The polypeptides can be prepared by gene manipulation and are suitable, alone or in combination with lymphokines, as pharmaceuticals.
    Type: Grant
    Filed: June 15, 1987
    Date of Patent: October 20, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Klaus Schollmeier, Achim Moeller, Wolfgang Koerwer, Thomas Doerper, Heinz Hillen, Lothar Daum, Franz Emling, Gerhard Keilhauer
  • Patent number: 4959484
    Abstract: Novel strobilurine derivatives which are suitable for the treatment of disorders and as fungicides are described.
    Type: Grant
    Filed: April 14, 1989
    Date of Patent: September 25, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Lothar Daum, Gerhard Keilhauer, Gisela Lorenz, Eberhard Ammermann, Wolfgang Weber, Wolfgang Steglich, Bert Steffan, Angela Scherer
  • Patent number: 4874863
    Abstract: Bisnaphthalimides of the formula I ##STR1## where X.sup.1 to X.sup.4 and R have the meanings stated in the description, and their preparation are described. The compounds are cytotoxic towards human cells in vitro.
    Type: Grant
    Filed: March 1, 1988
    Date of Patent: October 17, 1989
    Assignee: Knoll AG
    Inventors: Miguel F. Brana, Jose M. C. Berlanga, Gerhard Keilhauer, Erich Schlick