Patents by Inventor Gerhard Konig

Gerhard Konig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKERS FOR DIAGNOSING ALZHEIMER'S DISEASE
    Publication number: 20140194318
    Abstract: A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies detection of specific peptide markers, e.g., using mass spectrometric analysis.
    Type: Application
    Filed: March 18, 2014
    Publication date: July 10, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Õzkan Yalkinoglu, Gerhard König, Denis F. Hochstrasser, Jean-Charles Sanchez, Odile Carrette
  • Biomarkers for diagnosing alzheimer's disease
    Patent number: 8772042
    Abstract: A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies detection of specific peptide markers, e.g., using mass spectrometric analysis.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: July 8, 2014
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Özkan Yalkinoglu, Gerhard König, Denis Francois Hochstrasser, Jean-Charles Sanchez, Odile Carrette
  • BIOMARKERS FOR DIAGNOSING ALZHEIMER'S DISEASE
    Publication number: 20120016205
    Abstract: A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies detection of specific peptide markers, e.g., using mass spectrometric analysis.
    Type: Application
    Filed: May 2, 2011
    Publication date: January 19, 2012
    Applicant: BAYER HEALTHCARE AG
    Inventors: Õzkan Yalkinoglu, Gerhard Kõnig, Denis Francois Hochstrasser, Jean-Charles Sanchez, Odile Carrette
  • MORPHINE-BRIDGED INDAZOLE DERIVATIVES
    Publication number: 20090023717
    Abstract: The present invention relates to novel morpholine-bridged indazole derivatives which stimulate soluble guanylate cyclase, to process for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of disorders of the central nervous system.
    Type: Application
    Filed: September 18, 2008
    Publication date: January 22, 2009
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard Konig, Johannes-Peter Stasch, Frank Wunder, Dieter Lang, Elke Stahl, Thomas Schenke, Rudy Schreiber
  • Morpoline-bridged indazole derivatives
    Patent number: 7427617
    Abstract: The present invention relates to novel morpholine-bridged indazole derivatives having the formula which stimulate soluble guanylate cyclase, to a process for the preparation thereof, and to pharmaceutical compositions containing them. These compounds are useful for the treatment of disorders of the central nervous system.
    Type: Grant
    Filed: September 16, 2003
    Date of Patent: September 23, 2008
    Assignee: Bayer Healthcare AG
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard König, Johannes-Peter Stasch, Frank Wunder, Dieter Lang, Elke Stahl, Thomas Schenke, Rudy Schreiber
  • 4-amino-substituted pyrimidine derivatives
    Patent number: 7410973
    Abstract: The present invention relates to novel 4-amino-substituted pyrimidine derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of central nervous system diseases.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: August 12, 2008
    Assignee: Bayer Healthcare AG
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard König, Johannes-Peter Stasch, Elke Stahl, Rudy Schreiber, Frank Wunder, Dieter Lang
  • Compression Ignition Internal Combustion Engine
    Publication number: 20080135014
    Abstract: A method for operating an internal combustion engine, injects fuel directly into a combustion chamber as a main injection, a postinjection and optionally also as a preinjection. An injection nozzle with a plurality of injection bores effects the preinjection and the postinjection preferably which is carried out cyclically. To minimize wetting of the combustion chamber walls, during the postinjection the partial quantities of fuel and a lift of the nozzle needle of the injection nozzle are set so that, for each partial quantity of the postinjection injected into the combustion chamber, the reach of the respective fuel jet in the combustion chamber is limited and the reach is less than the distance to a combustion chamber boundary.
    Type: Application
    Filed: June 25, 2004
    Publication date: June 12, 2008
    Applicant: DaimlerChrysler AG
    Inventors: Matthias Blessing, Harald Braun, Frank Keller, Gerhard Konig, Christian Krueger, Alois Raab
  • Biomarkers for diagnosing alzheimer's disease
    Publication number: 20060240561
    Abstract: A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies detection of specific peptide markers, e.g., using mass spectrometric analysis.
    Type: Application
    Filed: August 11, 2003
    Publication date: October 26, 2006
    Inventors: Ozkan Yalkinoglu, Gerhard Konig, Denis Hochstrasser, Jean-Charles Sanchez, Odile Carrette
  • 2,5-disubstituted pyrimidine derivatives
    Patent number: 7091198
    Abstract: The present invention relates to novel 2,5-disubstituted pyrimidine derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of central nervous system diseases.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: August 15, 2006
    Assignee: Bayer HealthCare AG
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard König, Johannes-Peter Stasch, Elke Stahl, Rudy Schreiber, Frank Wunder
  • Reduction-stable zinc ferrite pigments, process for producing them and their use
    Publication number: 20060162613
    Abstract: The present invention relates to zinc ferrite pigments, to a process for producing them and to their use. It relates in particular to pale, yellow zinc ferrite pigments featuring enhanced reduction stability.
    Type: Application
    Filed: January 12, 2006
    Publication date: July 27, 2006
    Inventors: Carsten Rosenhahn, Udo Krauter, Ralf-Gerhard Konig
  • 2,5-DISUBSTITUTED PYRIMIDINE DERIVATIVES
    Publication number: 20060167016
    Abstract: The present invention relates to novel 2,5-disubstituted pyrimidine derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of central nervous system diseases.
    Type: Application
    Filed: July 7, 2003
    Publication date: July 27, 2006
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard Konig, Johannes-Peter Stasch, Elke Stahl, Rudy Schreiber, Frank Wunder
  • Morpoline-bridged indazole derivatives
    Publication number: 20060128700
    Abstract: The present invention relates to novel morpholine-bridged indazole derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of disorders of the central nervous system.
    Type: Application
    Filed: September 16, 2003
    Publication date: June 15, 2006
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard Konig, Johannes-Peter Stasch, Frank Wunder, Dieter Lang, Elke Stahl, Thomas Schenke, Rudy Schreiber
  • Selective PDE 2 inhibitors as pharmaceuticals for improving perception
    Patent number: 7022709
    Abstract: The invention relates to the use of selective phosphodiesterase 2 (PDE 2) inhibitors for producing pharmaceuticals for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: July 23, 2001
    Date of Patent: April 4, 2006
    Inventors: Frank-Gerhard Böss, Martin Hendrix, Gerhard König, Ulrich Niewöhner, Karl-Heinz Schlemmer, Rudy Schreiber, Franz-Josef Van Der Staay, Dagmar Schauss
  • Substituted imidazotriazinones
    Patent number: 6998402
    Abstract: The invention relates to novel substituted imidazotriazinones, to a method for their production and to the use thereof for producing medicaments, in particular to improve perception, powers of concentration, learning capacity and/or memory retentiveness.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: February 14, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Maria Theresia Niewöhner, legal representative, Dagmar Schauss, Gerhard König, Martin Hendrix, Frank-Gerhard Böss, Franz-Josef van der Staay, Rudy Schreiber, Karl-Heinz Schlemmer, Toshiya Moriwaki, Ulrich Niewöhner, deceased
  • 4-amino-substituted pyrimidine derivatives
    Publication number: 20060014951
    Abstract: The present invention relates to novel 4-amino-substituted pyrimidine derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of central nervous system diseases.
    Type: Application
    Filed: July 7, 2003
    Publication date: January 19, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard Konig, Johannes-Peter Stasch, Elke Stahl, Rudy Schreiber, Frank Wunder, Dieter Lang
  • Phenyl sulfoxides and phenyl sulfones
    Publication number: 20050227995
    Abstract: The invention relates to phenyl sulfoxides and sulfones and processes for their preparation, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially Alzheimer's disease.
    Type: Application
    Filed: January 7, 2003
    Publication date: October 13, 2005
    Inventors: Martin Hendrix, Karlheinz Baumann, Rolf Grosser, Gerhard Konig, Vera Dusterhus, Joachim Kruger
  • Novel substituted imidazotriazinones
    Publication number: 20050009822
    Abstract: The invention relates to novel substituted imidazotriazinones, to a method for their production and to the use thereof for producing medicaments, in particular to improve perception, powers of concentration, learning capacity and/or memory retentiveness.
    Type: Application
    Filed: February 11, 2002
    Publication date: January 13, 2005
    Inventors: Ulrich Niewohner, Maria Niewohner, Dagmar Schauss, Gerhard Konig, Martin Hendrix, Frank-Gerhard Boss, Franz-Josef Staay, Rudy Schreiber, Karl-Heinz Schlemmer, Toshiya Moriwaki
  • Method for the injection of fuel
    Patent number: 6644268
    Abstract: In a method for the injection of Diesel fuel into a combustion chamber of a Diesel engine by way of a fuel injection valve with a plurality of pilot and main fuel injection ports, the fuel is injected during partial load operation only by way of the pilot injection ports such that a homogeneous mixture is formed and, under full load operation, fuel is additionally injected—after a pause—through the main fuel injection ports in such a way that a fuel jet bundle is formed in combination with the fuel jets formed by the pilot ports which is extends over the whole periphery of the combustion chamber. The fuel injection valve has the main fuel ports arranged in a piezo-actuated tappet in series in the direction of the opening movement of the tappet behind the associated pilot ports. With the piezo drive the opening stroke of the tappet can be controlled so as to provide fuel injection pauses between the pilot fuel injection and the main fuel injection.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: November 11, 2003
    Assignee: DaimlerChrysler AG
    Inventors: Gerhard König, Heinz Öing, Gregor Renner
  • Substituted imidazotriazinones
    Patent number: 6573263
    Abstract: The present invention relates to new substituted imidazotriazinones, processes for their preparation, and their use for the production of medicaments, in particular for improving perception, concentration power, learning power and/or memory power.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: June 3, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewöhner, Dagmar Schauss, Martin Hendrix, Gerhard König, Frank-Gerhard Böss, Franz-Josef Van Der Staay, Rudy Schreiber, Karl-Heinz Schlemmer, Rolf Grosser
  • Method for operating a reciprocating-piston internal combustion engine
    Patent number: 6505601
    Abstract: A method for operating a reciprocating-piston internal combustion engine with direct fuel injection.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: January 14, 2003
    Assignee: DaimlerChrysler AG
    Inventors: Rainer Werner Jorach, Gerhard König, Alois Raab, Eckart Schloz, Petra Stapf