Patents by Inventor Gerhard Laub

Gerhard Laub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11730388
    Abstract: In the field of MRI, a model-based MRI image reconstruction technique is provided. The model-based reconstruction technique increases the performance of Time-of-Flight MRA. In a learning phase, a model is calculated from a sufficiently large set of data acquired at both low and high magnetic fields, using deep learning strategies. In a clinical phase, the model is applied to measured data generating high MR image quality.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: August 22, 2023
    Assignee: SIEMENS HEALTHCARE GMBH
    Inventors: Gerhard Laub, Peter Schmitt, David Grodzki, Waqas Majeed, Wuyi Zhao
  • Publication number: 20200405175
    Abstract: In the field of MRI, a model-based MRI image reconstruction technique is provided. The model-based reconstruction technique increases the performance of Time-of-Flight MRA. In a learning phase, a model is calculated from a sufficiently large set of data acquired at both low and high magnetic fields, using deep learning strategies. In a clinical phase, the model is applied to measured data generating high MR image quality.
    Type: Application
    Filed: June 10, 2020
    Publication date: December 31, 2020
    Applicant: Siemens Healthcare GmbH
    Inventors: Gerhard LAUB, Peter SCHMITT, David GRODZKI, Waqas MAJEED, Wuyi ZHAO
  • Patent number: 10649056
    Abstract: Embodiments can provide a computer-implemented method for free breathing three dimensional diffusion imaging, the method comprising initiating, via a k-space component processor, diffusion/T2 preparation, comprising generating diffusion contrast; and adjusting one or more of amplitude, duration, and polarity to set a first order moment; applying, via an image data processor, a stack of stars k-space ordering, comprising acquiring a radial/spiral view for all members of a plurality of partitions in a partition-encoding direction; increasing an azimuthal angle until a complete set of radial/spiral views are sampled; and applying diffusion gradients along each of three axis simultaneously; and calculating, via the image data processor, an apparent diffusion coefficient map.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: May 12, 2020
    Assignees: Siemens Healthcare GmbH, Cedars-Sinai Medical Center
    Inventors: Xiaoming Bi, Christopher T. Nguyen, Zhaoyang Fan, Yutaka Natsuaki, Debiao Li, Gerhard Laub
  • Patent number: 10605880
    Abstract: A method for performing 3D body imaging includes performing a 3D MRI acquisition of a patient to acquire k-space data and dividing the k-space data into k-space data bins. Each bin includes a portion of the k-space data corresponding to a distinct breathing phase. 3D image sets are reconstructed from the bins, with each 3D image set corresponding to a distinct k-space data bin. For each bin other than a selected reference bin, forward and inverse transforms are calculated between the 3D image set corresponding to the bin and the 3D image set corresponding to the reference bin. Then, a motion corrected and averaged image is generated for each bin by (a) aligning the 3D image set from each other bin to the 3D image set corresponding to the bin using the transforms, and (b) averaging the aligned 3D image sets to yield the motion corrected and averaged image.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: March 31, 2020
    Assignees: Siemens Healthcare GmbH, Cedars-Sinai Medical Center
    Inventors: Xiaoming Bi, Jianing Pang, Zhaoyang Fan, Matthias Fenchel, Gerhard Laub, Debiao Li
  • Patent number: 10534056
    Abstract: A system uses multiple RF coils in MR imaging and an RF (Radio Frequency) signal generator generates RF excitation pulses in anatomical regions of interest and enables subsequent acquisition of associated RF echo data. A magnetic field gradient generator generates anatomical volume select magnetic field gradients for phase encoding and readout RF data acquisition. The RF signal generator and the gradient generator substantially concurrently acquire first and second volumes of first and second different anatomical regions by providing, a first RF pulse having a first asymmetric shape followed by a successive second RF pulse substantially having the first asymmetric shape but reversed in time, to substantially reduce echo time (TE) differences between acquisition of the first and second volumes and a phase encoding magnetic field gradient prepares for acquisition of data representing the first and second volumes.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: January 14, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Vibhas S Deshpande, Gerhard Laub
  • Patent number: 10354416
    Abstract: A method for acquiring an image volume using a magnetic resonance imaging device includes performing an acquisition process to acquire a first dataset corresponding to a first portion of an anatomical region of interest at a first slice resolution, wherein the first dataset comprises a first plurality of three-dimensional slabs or a first plurality of two-dimensional slice regions. Additionally, one or more additional acquisition processes is performed to acquire a second dataset corresponding to a second portion of the anatomical region of interest at a second slice resolution that is lower or higher than the first slice resolution, wherein the second dataset comprises a second plurality of three-dimensional slabs or a second plurality of two-dimensional slice regions. Once the datasets are acquired, a reconstruction process is applied to jointly reconstruct the first dataset and the second dataset as a single consistent volume.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: July 16, 2019
    Assignee: Siemens Healthcare GmbH
    Inventors: Yutaka Natsuaki, Xiaoming Bi, Gerhard Laub
  • Publication number: 20190079155
    Abstract: Embodiments can provide a computer-implemented method for free breathing three dimensional diffusion imaging, the method comprising initiating, via a k-space component processor, diffusion/T2 preparation, comprising generating diffusion contrast; and adjusting one or more of amplitude, duration, and polarity to set a first order moment; applying, via an image data processor, a stack of stars k-space ordering, comprising acquiring a radial/spiral view for all members of a plurality of partitions in a partition-encoding direction; increasing an azimuthal angle until a complete set of radial/spiral views are sampled; and applying diffusion gradients along each of three axis simultaneously; and calculating, via the image data processor, an apparent diffusion coefficient map.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 14, 2019
    Inventors: Xiaoming Bi, Christopher T. Nguyen, Zhaoyang Fan, Yutaka Natsuaki, Debiao Li, Gerhard Laub
  • Patent number: 10197658
    Abstract: A method for using flexible triggered segmentation to optimize magnetic resonance imaging includes partitioning a k-space table into a plurality of k-space segments, each respective k-space segment comprising one or more phase-encoding steps from a plurality of slice-encoding lines. A cardiac cycle is monitored using an electrical signal tracking system and used to trigger acquisition of the plurality of k-space segments over a plurality of acquisition windows.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: February 5, 2019
    Assignee: Siemens Healthcare GmbH
    Inventors: Yutaka Natsuaki, Randall Kroeker, Gerhard Laub, Peter Schmitt
  • Patent number: 10145926
    Abstract: A system includes applying, to patient tissue, a first imaging sequence comprising first balanced gradient pulse trains and RF pulses, where phases of successive RF pulses in the first imaging sequence differ by a first pulse phase increment, detecting first signals emitted from the patient tissue in response to the first imaging sequence, and to generate a first image based on the first signals, applying, to the patient tissue, a second imaging sequence comprising second balanced gradient pulse trains and RF pulses, where phases of successive RF pulses in the second imaging sequence differ by a second pulse phase increment different from the first pulse phase increment, detecting second signals emitted from the patient tissue in response to the second imaging sequence, and to generate a second image based on the second signals, applying motion-correction processing to the first image to generate a first motion-corrected image, applying motion-correction processing to the second image to generate a second mot
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: December 4, 2018
    Assignee: Siemens Healthcare GmbH
    Inventors: Xiaoming Bi, Yutaka Natsuaki, Kevin Johnson, Gerhard Laub
  • Patent number: 10052033
    Abstract: A magnetic resonance method and system are provided for providing improved 3D imaging of blood vessels and the like, which provides suppression of both blood and fat signals and is insensitive to subject motion, thereby facilitating improved visualization of vessel walls. The image data pulse sequence includes a plurality of pulse series, where each series includes a dark-blood sequence, a fat-suppression sequence, and a data readout sequence. Each data readout sequence samples a particular radial direction within each partition (Kz value) that passes through the Kz axis, and different radial orientations are sampled in subsequent series to provide a stack-of-stars sampling scheme.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: August 21, 2018
    Assignees: Siemens Healthcare GmbH, Cedars-Sinai Medical Center
    Inventors: Xiaoming Bi, Yutaka Natsuaki, Zhaoyang Fan, Debiao Li, Gerhard Laub
  • Publication number: 20170330353
    Abstract: A method for acquiring an image volume using a magnetic resonance imaging device includes performing an acquisition process to acquire a first dataset corresponding to a first portion of an anatomical region of interest at a first slice resolution, wherein the first dataset comprises a first plurality of three-dimensional slabs or a first plurality of two-dimensional slice regions. Additionally, one or more additional acquisition processes is performed to acquire a second dataset corresponding to a second portion of the anatomical region of interest at a second slice resolution that is lower or higher than the first slice resolution, wherein the second dataset comprises a second plurality of three-dimensional slabs or a second plurality of two-dimensional slice regions. Once the datasets are acquired, a reconstruction process is applied to jointly reconstruct the first dataset and the second dataset as a single consistent volume.
    Type: Application
    Filed: May 12, 2016
    Publication date: November 16, 2017
    Inventors: Yutaka Natsuaki, Xiaoming Bi, Gerhard Laub
  • Publication number: 20170328970
    Abstract: A method for performing 3D body imaging includes performing a 3D MRI acquisition of a patient to acquire k-space data and dividing the k-space data into k-space data bins. Each bin includes a portion of the k-space data corresponding to a distinct breathing phase. 3D image sets are reconstructed from the bins, with each 3D image set corresponding to a distinct k-space data bin. For each bin other than a selected reference bin, forward and inverse transforms are calculated between the 3D image set corresponding to the bin and the 3D image set corresponding to the reference bin. Then, a motion corrected and averaged image is generated for each bin by (a) aligning the 3D image set from each other bin to the 3D image set corresponding to the bin using the transforms, and (b) averaging the aligned 3D image sets to yield the motion corrected and averaged image.
    Type: Application
    Filed: May 9, 2017
    Publication date: November 16, 2017
    Inventors: Xiaoming Bi, Jianing Pang, Zhaoyang Fan, Matthias Fenchel, Gerhard Laub, Debiao Li
  • Publication number: 20170153310
    Abstract: A system includes applying, to patient tissue, a first imaging sequence comprising first balanced gradient pulse trains and RF pulses, where phases of successive RF pulses in the first imaging sequence differ by a first pulse phase increment, detecting first signals emitted from the patient tissue in response to the first imaging sequence, and to generate a first image based on the first signals, applying, to the patient tissue, a second imaging sequence comprising second balanced gradient pulse trains and RF pulses, where phases of successive RF pulses in the second imaging sequence differ by a second pulse phase increment different from the first pulse phase increment, detecting second signals emitted from the patient tissue in response to the second imaging sequence, and to generate a second image based on the second signals, applying motion-correction processing to the first image to generate a first motion-corrected image, applying motion-correction processing to the second image to generate a second mot
    Type: Application
    Filed: November 30, 2015
    Publication date: June 1, 2017
    Inventors: Xiaoming Bi, Yutaka Natsuaki, Kevin Johnson, Gerhard Laub
  • Publication number: 20160266223
    Abstract: A magnetic resonance method and system are provided for providing improved 3D imaging of blood vessels and the like, which provides suppression of both blood and fat signals and is insensitive to subject motion, thereby facilitating improved visualization of vessel walls. The image data pulse sequence includes a plurality of pulse series, where each series includes a dark-blood sequence, a fat-suppression sequence, and a data readout sequence. Each data readout sequence samples a particular radial direction within each partition (Kz value) that passes through the Kz axis, and different radial orientations are sampled in subsequent series to provide a stack-of-stars sampling scheme.
    Type: Application
    Filed: February 8, 2016
    Publication date: September 15, 2016
    Inventors: Xiaoming Bi, Yutaka Natsuaki, Zhaoyang Fan, Debiao Li, Gerhard Laub
  • Patent number: 9442961
    Abstract: A system orders acquisition of frequency domain components representing MR image data for storage in a storage array (e.g., k-space). A storage array of individual data elements stores corresponding individual frequency components comprising an MR dataset. The array of individual data elements has a designated center and individual data elements individually have a radius to the designated center. A magnetic field generator generates a magnetic field for use in acquiring multiple individual frequency components corresponding to individual data elements in the storage array. The individual frequency components are successively acquired in an order in which radius of respective corresponding individual data elements increases and decreases as the multiple individual frequency components are sequentially acquired during acquisition of an MR dataset representing an MR image.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: September 13, 2016
    Assignees: Siemens Medical Solutions USA, Inc., Siemens Aktiengesellschaft
    Inventors: Peter Schmitt, Gerhard Laub, Yutaka Natsuaki, Randall Kroeker
  • Publication number: 20150038829
    Abstract: A method for using flexible triggered segmentation to optimize magnetic resonance imaging includes partitioning a k-space table into a plurality of k-space segments, each respective k-space segment comprising one or more phase-encoding steps from a plurality of slice-encoding lines. A cardiac cycle is monitored using an electrical signal tracking system and used to trigger acquisition of the plurality of k-space segments over a plurality of acquisition windows.
    Type: Application
    Filed: July 11, 2014
    Publication date: February 5, 2015
    Inventors: Yutaka Natsuaki, Randall Kroeker, Gerhard Laub, Peter Schmitt
  • Publication number: 20140002077
    Abstract: A system uses multiple RF coils in MR imaging and an RF (Radio Frequency) signal generator generates RF excitation pulses in anatomical regions of interest and enables subsequent acquisition of associated RF echo data. A magnetic field gradient generator generates anatomical volume select magnetic field gradients for phase encoding and readout RF data acquisition. The RF signal generator and the gradient generator substantially concurrently acquire first and second volumes of first and second different anatomical regions by providing, a first RF pulse having a first asymmetric shape followed by a successive second RF pulse substantially having the first asymmetric shape but reversed in time, to substantially reduce echo time (TE) differences between acquisition of the first and second volumes and a phase encoding magnetic field gradient prepares for acquisition of data representing the first and second volumes.
    Type: Application
    Filed: April 5, 2013
    Publication date: January 2, 2014
    Applicant: SIEMENS MEDICAL SOLUTIONS USA, INC.
    Inventors: Vibhas S. Deshpande, Gerhard Laub
  • Publication number: 20130119990
    Abstract: A system orders acquisition of frequency domain components representing MR image data for storage in a storage array (e.g., k-space). A storage array of individual data elements stores corresponding individual frequency components comprising an MR dataset. The array of individual data elements has a designated center and individual data elements individually have a radius to the designated center. A magnetic field generator generates a magnetic field for use in acquiring multiple individual frequency components corresponding to individual data elements in the storage array. The individual frequency components are successively acquired in an order in which radius of respective corresponding individual data elements increases and decreases as the multiple individual frequency components are sequentially acquired during acquisition of an MR dataset representing an MR image.
    Type: Application
    Filed: January 8, 2013
    Publication date: May 16, 2013
    Applicants: Siemens Aktiengesellschaft, Siemens Medical Solutions USA, Inc.
    Inventors: Peter Schmitt, Gerhard Laub, Yutaka Natsuaki, Randall Kroeker
  • Patent number: 8378678
    Abstract: A system orders acquisition of frequency domain components representing MR image data for storage in a storage array (e.g., k-space). A storage array of individual data elements stores corresponding individual frequency components comprising an MR dataset. The array of individual data elements has a designated center and individual data elements individually have a radius to the designated center. A magnetic field generator generates a magnetic field for use in acquiring multiple individual frequency components corresponding to individual data elements in the storage array. The individual frequency components are successively acquired in an order in which radius of respective corresponding individual data elements increases and decreases as the multiple individual frequency components are sequentially acquired during acquisition of an MR dataset representing an MR image.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: February 19, 2013
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Peter Schmitt, Gerhard Laub, Yutaka Natsuaki, Randall Kroeker
  • Patent number: 8378680
    Abstract: An MR imaging system without the use of a contrast agent, in a first repetition time interval, generates a non-selective magnetization preparation pulse for magnetizing an anatomical volume encompassing blood flowing into a selected slab within the volume for blood signal suppression, generates RF excitation pulses and acquires a first MR imaging dataset of the selected slab within the volume with a suppressed blood signal. The system in a second repetition time interval succeeding the first repetition time interval, generates a selected slab magnetization preparation pulse for magnetizing the selected slab, generates RF excitation pulses and acquires a second MR imaging dataset of the selected slab within the volume. An image data processor substantially subtracts imaging data of the first MR imaging dataset from the second MR imaging dataset to provide an image enhancing a vessel structure in the selected slab and also substantially averages imaging data to provide an MR anatomical image.
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: February 19, 2013
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: John William Grinstead, Gerhard Laub