Patents by Inventor Gerhard Matthias Kresbach

Gerhard Matthias Kresbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8053225
    Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: November 8, 2011
    Assignee: Bayer Technology Services GmbH
    Inventors: Eveline Schürmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Schärer-Hernández, Eginhard Schick
  • Patent number: 7927868
    Abstract: A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The sealing layer includes a multitude of recesses at least open towards the sensor platform, which form a corresponding multitude of sample compartments in a 2-dimensional arrangement.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: April 19, 2011
    Assignee: Bayer Technology Services GmbH
    Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Eveline Schürmann-Mader
  • Publication number: 20100227773
    Abstract: A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The sealing layer includes a multitude of recesses at least open towards the sensor platform, which form a corresponding multitude of sample compartments in a 2-dimensional arrangement.
    Type: Application
    Filed: March 17, 2010
    Publication date: September 9, 2010
    Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Eveline Schürmann-Mader
  • Patent number: 7708945
    Abstract: A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The sealing layer includes a multitude of recesses at least open towards the sensor platform, which form a corresponding multitude of sample compartments in a 2-dimensional arrangement.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: May 4, 2010
    Assignee: Bayer Technology Services GmbH
    Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Eveline Schürmann-Mader
  • Patent number: 7678565
    Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: March 16, 2010
    Assignee: Bayer Technology Services GmbH
    Inventors: Eveline Schürmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Schärer-Hernández, Eginhard Schick
  • Patent number: 7645612
    Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a), at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes, means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionally means for the calibration of one or more luminescences gen
    Type: Grant
    Filed: April 4, 2008
    Date of Patent: January 12, 2010
    Assignee: Bayer Technology Services GmbH
    Inventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schürmann-Mader, Martin Andreas Bopp
  • Publication number: 20080299008
    Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.
    Type: Application
    Filed: February 21, 2008
    Publication date: December 4, 2008
    Inventors: Eveline Schurmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Scharer-Hernandez, Eginhard Schick
  • Publication number: 20080212070
    Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a), at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes, means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionally means for the calibration of one or more luminescences gen
    Type: Application
    Filed: April 4, 2008
    Publication date: September 4, 2008
    Inventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schurmann-Mader, Martin Andreas Bopp
  • Patent number: 7396675
    Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a), at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes, means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionally means for the calibration of one or more luminescences gen
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: July 8, 2008
    Assignee: Bayer Technology Services GmbH
    Inventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schürmann-Mader, Martin Andreas Bopp
  • Patent number: 7358079
    Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.
    Type: Grant
    Filed: December 13, 2000
    Date of Patent: April 15, 2008
    Assignee: Bayer Technology Services GmbH
    Inventors: Eveline Schürmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Schärer-Hernández, Eginhard Schick
  • Publication number: 20040058385
    Abstract: The invention relates to various embodiments of a kit for simultaneous qualitative and/or quantitative determination of numerous analytes, which in particular enables the density of immobilized biological or biochemical or synthetic recognition elements for the determination of said analytes, i.e. the coating density of the measurement area dedicated for these recognition elements, to be referenced. The invention also relates to analytical systems based on the kit according the invention as well as to methods carried out therewith to determine one or more analytes and the use thereof.
    Type: Application
    Filed: May 15, 2003
    Publication date: March 25, 2004
    Inventors: Andreas Peter Abel, Gerhard Matthias Kresbach, Gert Ludwig Duveneck, Nania Graciela Scharer-Hernandez
  • Publication number: 20040046128
    Abstract: A sensor platform, based on a planar optical thin-film waveguide is used to determine one or more luminescences from one or more measurement areas on the sensor platform. The sensor platform has a first optically transparent layer on a second optically transparent layer of lower refractive index than the first optically transparent layer, and at least one grating structure to incouple excitation light to the measurement areas or to outcouple luminescence light from the measurement areas. An optical system is also used for luminescence determination. Further, an analytical system having the sensor platform, the optical system, and a supply device to bring one or more samples in contact with the measurement areas on the sensor platform is used for luminescence determination.
    Type: Application
    Filed: August 28, 2003
    Publication date: March 11, 2004
    Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach
  • Publication number: 20030148542
    Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising
    Type: Application
    Filed: November 27, 2002
    Publication date: August 7, 2003
    Inventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schurmann-Mader, Martin Andreas Bopp
  • Publication number: 20020182631
    Abstract: The invention is related to a one- or two-dimensional arrangement of flow cells, as part of an array of sample compartments, with at least one in- and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with said base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.
    Type: Application
    Filed: June 17, 2002
    Publication date: December 5, 2002
    Inventors: Eveline Schurmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Scharer-Hernandez, Eginhard Schick
  • Publication number: 20020074513
    Abstract: The invention is related to a variable embodiment of a sensor platform based on a planar thin-film waveguide for the determination of one or more luminescences from one or more measurement areas on said sensor platform, comprising an optical film waveguide of different layers (“stratified waveguide”) with a first optically transparent layer (a) on a second optically transparent layer (b) of lower refractive index than layer (a) and at least one grating structure for the incoupling of excitation light to the measurement areas or outcoupling of luminescence light from the measurement areas. The invention is also related to an optical system for luminescence determination and to an analytical system, comprising a sensor platform according to the invention, an optical system according to the invention, and supply means for contacting one or more samples with the measurement areas on the sensor platform.
    Type: Application
    Filed: December 4, 2001
    Publication date: June 20, 2002
    Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach