Patents by Inventor Gerhard Matthias Kresbach
Gerhard Matthias Kresbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8053225Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: GrantFiled: January 28, 2010Date of Patent: November 8, 2011Assignee: Bayer Technology Services GmbHInventors: Eveline Schürmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Schärer-Hernández, Eginhard Schick
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Patent number: 7927868Abstract: A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The sealing layer includes a multitude of recesses at least open towards the sensor platform, which form a corresponding multitude of sample compartments in a 2-dimensional arrangement.Type: GrantFiled: March 17, 2010Date of Patent: April 19, 2011Assignee: Bayer Technology Services GmbHInventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Eveline Schürmann-Mader
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Publication number: 20100227773Abstract: A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The sealing layer includes a multitude of recesses at least open towards the sensor platform, which form a corresponding multitude of sample compartments in a 2-dimensional arrangement.Type: ApplicationFiled: March 17, 2010Publication date: September 9, 2010Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Eveline Schürmann-Mader
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Patent number: 7708945Abstract: A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The sealing layer includes a multitude of recesses at least open towards the sensor platform, which form a corresponding multitude of sample compartments in a 2-dimensional arrangement.Type: GrantFiled: August 3, 2000Date of Patent: May 4, 2010Assignee: Bayer Technology Services GmbHInventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Eveline Schürmann-Mader
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Patent number: 7678565Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: GrantFiled: February 21, 2008Date of Patent: March 16, 2010Assignee: Bayer Technology Services GmbHInventors: Eveline Schürmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Schärer-Hernández, Eginhard Schick
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Patent number: 7645612Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a), at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes, means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionally means for the calibration of one or more luminescences genType: GrantFiled: April 4, 2008Date of Patent: January 12, 2010Assignee: Bayer Technology Services GmbHInventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schürmann-Mader, Martin Andreas Bopp
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Publication number: 20080299008Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: ApplicationFiled: February 21, 2008Publication date: December 4, 2008Inventors: Eveline Schurmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Scharer-Hernandez, Eginhard Schick
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Publication number: 20080212070Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a), at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes, means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionally means for the calibration of one or more luminescences genType: ApplicationFiled: April 4, 2008Publication date: September 4, 2008Inventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schurmann-Mader, Martin Andreas Bopp
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Patent number: 7396675Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a), at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes, means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionally means for the calibration of one or more luminescences genType: GrantFiled: May 25, 2001Date of Patent: July 8, 2008Assignee: Bayer Technology Services GmbHInventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schürmann-Mader, Martin Andreas Bopp
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Patent number: 7358079Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: GrantFiled: December 13, 2000Date of Patent: April 15, 2008Assignee: Bayer Technology Services GmbHInventors: Eveline Schürmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Schärer-Hernández, Eginhard Schick
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Publication number: 20040058385Abstract: The invention relates to various embodiments of a kit for simultaneous qualitative and/or quantitative determination of numerous analytes, which in particular enables the density of immobilized biological or biochemical or synthetic recognition elements for the determination of said analytes, i.e. the coating density of the measurement area dedicated for these recognition elements, to be referenced. The invention also relates to analytical systems based on the kit according the invention as well as to methods carried out therewith to determine one or more analytes and the use thereof.Type: ApplicationFiled: May 15, 2003Publication date: March 25, 2004Inventors: Andreas Peter Abel, Gerhard Matthias Kresbach, Gert Ludwig Duveneck, Nania Graciela Scharer-Hernandez
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Publication number: 20040046128Abstract: A sensor platform, based on a planar optical thin-film waveguide is used to determine one or more luminescences from one or more measurement areas on the sensor platform. The sensor platform has a first optically transparent layer on a second optically transparent layer of lower refractive index than the first optically transparent layer, and at least one grating structure to incouple excitation light to the measurement areas or to outcouple luminescence light from the measurement areas. An optical system is also used for luminescence determination. Further, an analytical system having the sensor platform, the optical system, and a supply device to bring one or more samples in contact with the measurement areas on the sensor platform is used for luminescence determination.Type: ApplicationFiled: August 28, 2003Publication date: March 11, 2004Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach
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Publication number: 20030148542Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprisingType: ApplicationFiled: November 27, 2002Publication date: August 7, 2003Inventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schurmann-Mader, Martin Andreas Bopp
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Publication number: 20020182631Abstract: The invention is related to a one- or two-dimensional arrangement of flow cells, as part of an array of sample compartments, with at least one in- and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with said base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: ApplicationFiled: June 17, 2002Publication date: December 5, 2002Inventors: Eveline Schurmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Scharer-Hernandez, Eginhard Schick
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Publication number: 20020074513Abstract: The invention is related to a variable embodiment of a sensor platform based on a planar thin-film waveguide for the determination of one or more luminescences from one or more measurement areas on said sensor platform, comprising an optical film waveguide of different layers (“stratified waveguide”) with a first optically transparent layer (a) on a second optically transparent layer (b) of lower refractive index than layer (a) and at least one grating structure for the incoupling of excitation light to the measurement areas or outcoupling of luminescence light from the measurement areas. The invention is also related to an optical system for luminescence determination and to an analytical system, comprising a sensor platform according to the invention, an optical system according to the invention, and supply means for contacting one or more samples with the measurement areas on the sensor platform.Type: ApplicationFiled: December 4, 2001Publication date: June 20, 2002Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach