Patents by Inventor Gerhard Pürstinger
Gerhard Pürstinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9242983Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: GrantFiled: April 8, 2014Date of Patent: January 26, 2016Assignees: K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
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Publication number: 20140221382Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: ApplicationFiled: April 8, 2014Publication date: August 7, 2014Applicant: GILEAD SCIENCES, INC.Inventors: Steven S. BONDY, David A. OARE, Gerhard PUERSTINGER
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Patent number: 8779141Abstract: The present invention relates to imidazo[4,5-c]pyridine compounds and pharmaceutical compositions for the treatment or prevention of viral infections, wherein the imidazo[4,5-c]pyridine compounds have the formula:Type: GrantFiled: May 19, 2009Date of Patent: July 15, 2014Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard PuerstingerInventors: Johan Neyts, Gerhard Pürstinger, Erik De Clercq
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Patent number: 8722677Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: GrantFiled: June 22, 2012Date of Patent: May 13, 2014Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
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Patent number: 8329727Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.Type: GrantFiled: October 13, 2009Date of Patent: December 11, 2012Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
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Publication number: 20120258969Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: ApplicationFiled: June 22, 2012Publication date: October 11, 2012Inventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
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Patent number: 8263612Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: GrantFiled: December 14, 2007Date of Patent: September 11, 2012Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
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Patent number: 7790730Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one compound having the general formula (A): wherein U is N or C; X is selected from C1-C10 alkylene, C2-10 alkenylene or C2-10 alkynylene, where each may include one or more intrachain heteroatoms selected from O, S, or NR11, provided any such heteroatom is not adjacent to the N in the ring; R3 is selected from aryl, aryloxy, arylthio, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl-N(R10)—, or heterocycle, where each said substituent is optionally substituted with at least one R17, provided that for cycloalkenyl the double bond is not adjacent to a nitrogen; and the other substituents are described in the specification.Type: GrantFiled: July 26, 2005Date of Patent: September 7, 2010Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Choung U. Kim, Johan Neyts, David A. Oare, Gerhard Puerstinger
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Patent number: 7737162Abstract: The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine derivative having the general formula (Z): (formula). The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula and their use as a medicine or to treat or prevent viral infections.Type: GrantFiled: July 3, 2003Date of Patent: June 15, 2010Assignee: Gilead Sciences, Inc.Inventors: Johan Neyts, Gerhard Pürstinger, Erik De Clercq
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Publication number: 20100028301Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.Type: ApplicationFiled: October 13, 2009Publication date: February 4, 2010Inventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
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Patent number: 7648998Abstract: The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening ofcompounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.Type: GrantFiled: December 21, 2004Date of Patent: January 19, 2010Assignees: K.U. Leuven Research & Development, Gilead Sciences, Inc.Inventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
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Publication number: 20090208456Abstract: The present invention relates to pharmaceutical compositions for the treatment of prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyrimidine having the general formula (A), wherein the substituents are described in the specification. The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula, their pharmaceutically acceptable formulations and their use as a medicine or to treat or prevent viral infections.Type: ApplicationFiled: July 26, 2005Publication date: August 20, 2009Applicants: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard PuerstingerInventors: Gerhard Puerstinger, Choung U. Kim, Johan Neyts, David A. Oare
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Publication number: 20080207678Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: ApplicationFiled: December 14, 2007Publication date: August 28, 2008Inventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
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Patent number: 7112680Abstract: The invention relates to novel 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones that are derived from 2-formylpyridine, 2-acylpyridines, acetyldiazines and acetyl(iso)quinolines. The invention also relates to a novel method for producing 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones and to their use as useful anti-cancer therapeutic agents. The novel compounds are also active against multidrug-resistant cancer cells.Type: GrantFiled: June 5, 2001Date of Patent: September 26, 2006Assignee: Austria Wirtschaftsservice Gesellschaft MIT Beschrankter HaftungInventors: Johann Hofmann, Gottfried Heinisch, Johnny Easmon, Gerhard Pürstinger, Heinz-Herbert Fiebig
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Publication number: 20060052602Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyrimidine having the general formula (A): wherein the substituents are described in the specification. The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula, their pharmaceutically acceptable formulations and their use as a medicine or to treat or prevent viral infections.Type: ApplicationFiled: July 26, 2005Publication date: March 9, 2006Inventors: Choung Kim, Johan Neyts, David Oare, Gerhard Puerstinger
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Publication number: 20050222198Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general formula (A): wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general formula and their use in the treatment or prophylaxis of viral infections.Type: ApplicationFiled: December 21, 2004Publication date: October 6, 2005Inventors: Steven Bondy, Eric Dowdy, Choung Kim, Johan Neyts, David Oare, Gerhard Puerstinger, Vahid Zia