Patents by Inventor Gerhard Pürstinger

Gerhard Pürstinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9242983
    Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: January 26, 2016
    Assignees: K.U. Leuven Research & Development
    Inventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
  • Publication number: 20140221382
    Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.
    Type: Application
    Filed: April 8, 2014
    Publication date: August 7, 2014
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Steven S. BONDY, David A. OARE, Gerhard PUERSTINGER
  • Patent number: 8779141
    Abstract: The present invention relates to imidazo[4,5-c]pyridine compounds and pharmaceutical compositions for the treatment or prevention of viral infections, wherein the imidazo[4,5-c]pyridine compounds have the formula:
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: July 15, 2014
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard Puerstinger
    Inventors: Johan Neyts, Gerhard Pürstinger, Erik De Clercq
  • Patent number: 8722677
    Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: May 13, 2014
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
  • Patent number: 8329727
    Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: December 11, 2012
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
  • Publication number: 20120258969
    Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.
    Type: Application
    Filed: June 22, 2012
    Publication date: October 11, 2012
    Inventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
  • Patent number: 8263612
    Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: September 11, 2012
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
  • Patent number: 7790730
    Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one compound having the general formula (A): wherein U is N or C; X is selected from C1-C10 alkylene, C2-10 alkenylene or C2-10 alkynylene, where each may include one or more intrachain heteroatoms selected from O, S, or NR11, provided any such heteroatom is not adjacent to the N in the ring; R3 is selected from aryl, aryloxy, arylthio, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl-N(R10)—, or heterocycle, where each said substituent is optionally substituted with at least one R17, provided that for cycloalkenyl the double bond is not adjacent to a nitrogen; and the other substituents are described in the specification.
    Type: Grant
    Filed: July 26, 2005
    Date of Patent: September 7, 2010
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Choung U. Kim, Johan Neyts, David A. Oare, Gerhard Puerstinger
  • Patent number: 7737162
    Abstract: The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine derivative having the general formula (Z): (formula). The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula and their use as a medicine or to treat or prevent viral infections.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: June 15, 2010
    Assignee: Gilead Sciences, Inc.
    Inventors: Johan Neyts, Gerhard Pürstinger, Erik De Clercq
  • Publication number: 20100028301
    Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.
    Type: Application
    Filed: October 13, 2009
    Publication date: February 4, 2010
    Inventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
  • Patent number: 7648998
    Abstract: The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening ofcompounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: January 19, 2010
    Assignees: K.U. Leuven Research & Development, Gilead Sciences, Inc.
    Inventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
  • Publication number: 20090208456
    Abstract: The present invention relates to pharmaceutical compositions for the treatment of prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyrimidine having the general formula (A), wherein the substituents are described in the specification. The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula, their pharmaceutically acceptable formulations and their use as a medicine or to treat or prevent viral infections.
    Type: Application
    Filed: July 26, 2005
    Publication date: August 20, 2009
    Applicants: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard Puerstinger
    Inventors: Gerhard Puerstinger, Choung U. Kim, Johan Neyts, David A. Oare
  • Publication number: 20080207678
    Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.
    Type: Application
    Filed: December 14, 2007
    Publication date: August 28, 2008
    Inventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
  • Patent number: 7112680
    Abstract: The invention relates to novel 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones that are derived from 2-formylpyridine, 2-acylpyridines, acetyldiazines and acetyl(iso)quinolines. The invention also relates to a novel method for producing 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones and to their use as useful anti-cancer therapeutic agents. The novel compounds are also active against multidrug-resistant cancer cells.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: September 26, 2006
    Assignee: Austria Wirtschaftsservice Gesellschaft MIT Beschrankter Haftung
    Inventors: Johann Hofmann, Gottfried Heinisch, Johnny Easmon, Gerhard Pürstinger, Heinz-Herbert Fiebig
  • Publication number: 20060052602
    Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyrimidine having the general formula (A): wherein the substituents are described in the specification. The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula, their pharmaceutically acceptable formulations and their use as a medicine or to treat or prevent viral infections.
    Type: Application
    Filed: July 26, 2005
    Publication date: March 9, 2006
    Inventors: Choung Kim, Johan Neyts, David Oare, Gerhard Puerstinger
  • Publication number: 20050222198
    Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general formula (A): wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general formula and their use in the treatment or prophylaxis of viral infections.
    Type: Application
    Filed: December 21, 2004
    Publication date: October 6, 2005
    Inventors: Steven Bondy, Eric Dowdy, Choung Kim, Johan Neyts, David Oare, Gerhard Puerstinger, Vahid Zia