Abstract: A device for characterizing particles of exhaled air. The device comprises an inlet line directed towards an outer environment with a filter for filtering particles. The inlet line is fluidly connected to a breathing line which comprises an interface through which air is breathable. A measurement line is fluidly connected to the breathing line and is fluidly connected to a particle measurement device for determining a parameter corresponding to the particles of the exhaled air. An inventive method comprises the following steps: Directing ex- haled air to a particle measurement device and determining a parameter corresponding to the particles of exhaled air, the parameter being at least one of the following parameters: Particle number, particle concentration (density), particle diameter, particle mass, particle size distribution, particle mass distribution, particle mass concentration, particle number concentration.

Abstract: The invention provides a compound, namely acetylsalicylic acid (ASA) or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising ASA or a pharmaceutically acceptable salt thereof, for use in the treatment of a patient, e.g. a human being, suffering from a severe influenza virus infection and/or a symptom or condition associated therewith (namely, nasal congestion, sore throat, cough, fever, fatigue, headache and myalgias), wherein said use comprises the administration of a composition comprising ASA or a pharmaceutically acceptable salt thereof to the patient by inhalation.

Abstract: The invention provides a compound, namely acetylsalicylic acid (ASA) or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising ASA or a pharmaceutically acceptable salt thereof, for use in the treatment of a patient, e.g. a human being, suffering from a severe influenza virus infection and/or a symptom or condition associated therewith (namely, nasal congestion, sore throat, cough, fever, fatigue, headache and myalgias), wherein said use comprises the administration of a composition comprising ASA or a pharmaceutically acceptable salt thereof to the patient by inhalation.

Abstract: The invention provides a compound, namely acetylsalicylic acid (ASA) or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising ASA or a pharmaceutically acceptable salt thereof, for use in the treatment of a patient, e.g. a human being, suffering from a severe influenza virus infection and/or a symptom or condition associated therewith (namely, nasal congestion, sore throat, cough, fever, fatigue, headache and myalgias), wherein said use comprises the administration of a composition comprising ASA or a pharmaceutically acceptable salt thereof to the patient by inhalation.

Abstract: A drug and device combination system used in a method for treatment of patients suffering from severe and oral corticosteroid-dependent asthma and other respiratory diseases requiring a treatment with orally administered steroids. The method for administration of the inhalable corticosteroid by a flow rate and volume regulated inhalation. The combination system of the inhalable corticosteroid and the device for regulating flow rate and volume of the inhalable corticosteroid and thus achieving delivery of said inhalable corticosteroid into the small airways of the lungs. The individually programmable device that assures safe and reproducible corticosteroid delivery compliant with treatment protocol.

Abstract: Methods, devices and compositions for treatment of severe and uncontrolled asthma are provided by which high amounts of an inhaled corticosteroid are directed to the small airways of the lower lungs. The invention provides for a substantial decrease in the dose of concurrently administered oral corticosteroids. A particular advantage of the invention is the significant reduction in corticosteroid-related adverse effects.

Abstract: The present invention is directed to the administration of aerosolized particles to specific area of the lungs, and in particular to the targeted delivery of aerosolized pharmaceutical formulations to a specific area of the lungs. More specifically, the present invention relates to devices and methods for depositing aerosolized particles to a specific area of the lungs by regulating aerosolizing parameters of the device. The present invention also relates to devices, systems and methods for disease management, where the aerosolizing parameters are adjusted based on monitoring at least one health parameter.

Abstract: A drug and device combination system used in a method for treatment of patients suffering from severe and oral corticosteroid-dependent asthma and other respiratory diseases requiring a treatment with orally administered steroids. The method for administration of the inhalable corticosteroid by a flow rate and volume regulated inhalation. The combination system of the inhalable corticosteroid and the device for regulating flow rate and volume of the inhalable corticosteroid and thus achieving delivery of said inhalable corticosteroid into the small airways of the lungs. The individually programmable device that assures safe and reproducible corticosteroid delivery compliant with treatment protocol.

Abstract: Methods, devices and compositions for treatment of severe and uncontrolled asthma are provided by which high amounts of an inhaled corticosteroid are directed to the small airways of the lower lungs. The invention provides for a substantial decrease in the dose of concurrently administered oral corticosteroids. A particular advantage of the invention is the significant reduction in corticosteroid-related adverse effects.

Abstract: An inhalation device may include a control and an air pump that is connected to the control. The air pump is controlled by the control such that the air pump supplies an inhalation flow, or inhalation volume or both according to a predetermined time course to a nebulizer connected to the air pump. The inhalation flow, inhalation volume or both is controlled by controlling the air pump, rather than by using valves.

Abstract: A method for treatment of severe and uncontrollable asthma by providing means for delivery of high doses of a suitable inhalable corticosteroid directly to the small airways of the lower lungs with substantial decrease in need for simultaneous administration of oral corticosteroids and with a significant reduction in undesirable secondary side effects in an oropharyngeal area. The method utilizes devices allowing individualization of treatment parameters in asthmatic patients having compromised breathing pattern due to severe and uncontrollable asthma.

Abstract: A device for the controlled inhalation of therapeutic aerosols comprises means providing individual patient parameters and/or aerosol parameters for the inhalation. The aerosol doses, such as the tidal volume and the respiratory flow, are individually adjusted on the basis of these individual parameters. Thus, the inhalation device may be individually adjusted to the patient to be treated.

Abstract: The invention relates to a component for an inhalation device comprising a first flow channel for inhalation, a second flow channel for exhalation, a mouthpiece forming a part of the first flow channel, a filter assigned to the second flow channel and a protection element which circumferentially surrounds the mouthpiece and is sealingly connected the mouthpiece at the end opposing the tip of the mouthpiece.

Abstract: The present invention is directed to the administration of aerosolized particles to specific area of the lungs, and in particular to the targeted delivery of aerosolized pharmaceutical formulations to a specific area of the lungs. More specifically, the present invention relates to devices and methods for depositing aerosolized particles to a specific area of the lungs by regulating aerosolizing parameters of the device. The present invention also relates to devices, systems and methods for disease management, where the aerosolizing parameters are adjusted based on monitoring at least one health parameter.

Abstract: The invention describes a means for the treatment of diseases of the tracheo-bronchial tract, particularly of COPD.

Abstract: An inhalation device comprising a control and an air pump connected to the control, the air pump being controlled by the control such that it supplies an inhalation flow, or inhalation volume or both according to a predetermined time course to a nebulizer connected to the air pump.

Abstract: The invention relates to a component for an inhalation device comprising a first flow channel for inhalation, a second flow channel for exhalation, a mouthpiece forming a part of the first flow channel, a filter assigned to the second flow channel and a protection element which circumferentially surrounds the mouthpiece and is sealingly connected the mouthpiece at the end opposing the tip of the mouthpiece.

Abstract: A stationary inhalation apparatus for the individual controlled inhalation of therapeutic aerosols comprises a drug-release means 3, at least one drug reservoir 2, a reader 4 for reading out a patient's individual parameters and/or the aerosol parameters stored in a memory means and a control unit connected to the drug-release means 3 and the reader 4 for releasing the drug as a function of the read-out parameters. This stationary inhalation apparatus 1 permits the administration of different drugs to a multitude of patients.

Abstract: The invention describes a means for the treatment of diseases of the tracheo-bronchial tract, particularly of COPD.

Abstract: The invention describes a means for the treatment of diseases of the tracheo-bronchial tract, particularly of COPD.