Patents by Inventor Gerhard Schlingmann

Gerhard Schlingmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation, characterization and structures of new antibiotic components produced by fungal culture 07F275
    Patent number: 5789604
    Abstract: New antibacterial agents produced by fungal culture 07F275, of which the compound designated 07F275 alpha having the following structure: ##STR1## is representative. Methods for the fermentation, recovery and purification from crude solutions are also disclosed.
    Type: Grant
    Filed: May 12, 1993
    Date of Patent: August 4, 1998
    Assignee: American Cyanamid Company
    Inventors: Cedric John Pearce, Robert West, Gerhard Schlingmann
  • Fungicidal agents LL-15G256.gamma.,.delta., and .epsilon. produced by LL-15G256 (Hypoxylon oceanicum)
    Patent number: 5747304
    Abstract: This invention provides new antifungal compounds of Formula I or II: ##STR1## wherein R, R.sup.1 and R.sup.2 are defined in the specification produced by culture LL-15G256 (Hypoxylon oceanicum), NRRL 21363 and their production by fermentation and use as antifungal agents.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: May 5, 1998
    Assignee: American Cyanamid Company
    Inventors: Gerhard Schlingmann, Lisa Milne, Cedric J. Pearce, E. B. Gareth Jones, David A. Albaugh
  • Antibiotic LL-D37187.alpha.
    Patent number: 5432193
    Abstract: This invention relates to antibiotic LL-D37187.alpha. derived from the microorganism Streptomyces which is useful as an antibacterial agent.
    Type: Grant
    Filed: May 14, 1993
    Date of Patent: July 11, 1995
    Assignee: American Cyanamid Company
    Inventors: Guy T. Carter, Gerhard Schlingmann, David P. Labeda, Joseph J. Goodman
  • Process for the preparation of optically pure diastereoisomers of tetrahydrofolate compounds using 10-formyltetrahydrofolate synthetase from clostridium
    Patent number: 5334535
    Abstract: A process for the preparation of optically pure diastereoisomers of tetrahydrofolate compounds is described, comprising the conversion, for example, of only the 5,6S,7,8-tetrahydrofolic acid component of a racemic mixture of 5,6,7,8-tetrahydrofolic acid to 10-formyl-5,6S,7,8-tetrahydrofolic acid in the presence of a formyl tetrahydrofolate synthetase, followed by cyclizing, hydrolyzing and derivatizing. The process is also useful to make a desired substantially pure (6R or 6S) enantiomer of a derivative of (radiolabeled) tetrahydrofolic acid or a salt or ester thereof.
    Type: Grant
    Filed: September 18, 1992
    Date of Patent: August 2, 1994
    Assignee: American Cyanamid Company
    Inventors: Gerhard Schlingmann, Stuart A. Rosenfeld
  • Process for obtaining metal-free corrinoids
    Patent number: 4407947
    Abstract: A process for obtaining metal-free corrinoids consisting of inoculating a culture media free of added compounds of metals of the VIIIth group of the Periodic Table with a parent strain of Rhodopseudomonas, cultivating under illumination, repeating the steps of inoculating and cultivating employing said culture media and said illumination employing a part of the sequential culture from the preceding stage as an inoculum in each subsequent state, for a series of several pre-production culture stages, inoculating said culture media with the preceding sequential culture for the last time, cultivating under illumination, separating the microorganism from the culture media of the production culture stage and isolating metal-free corrinoids from the culture media of the production culture stage.
    Type: Grant
    Filed: September 14, 1981
    Date of Patent: October 4, 1983
    Assignee: Gesellschaft fur Biotechnologische Forschung mbH (GBF)
    Inventors: Volker Koppenhagen, Gerhard Schlingmann, Bernd Dresow, Ludwig Bischoff, Rosemarie Penkert, Eicke Siefert
  • Process for producing metal corrinoids
    Patent number: 4311643
    Abstract: A process for producing red metal corrinoids comprising reacting yellow metal-free corrinoids having main absorptions .lambda..sub.max of 480 and 290 nm, in a liquid medium, with complex-forming metal ions to give yellow metal corrinoids, and alkalizing said metal corrinoids by treatment with an alkali.
    Type: Grant
    Filed: March 4, 1980
    Date of Patent: January 19, 1982
    Assignee: Gesellschaft fur Biotechnologische Forschung mbH
    Inventors: Volker Koppenhagen, Gerhard Schlingmann, Bernd Dresow, Ortrud Ebelmann