Abstract: The present invention concerns lyophilized pharmaceutical preparations of G-CSF that contain maltose, raffinose, sucrose, trehalose or amino sugar as stabilizing agents. In additon the invention concerns a process for the production of stabilized lyophilisates as well as the use of maltose, raffinose, sucrose, trehalose or amino sugar as stabilizing agents of pharmaceutical agents containing G-CSF.

Abstract: Aqueous pharmaceutical preparations of G-CSF are disclosed that are stable on storage and a buffer selected from the group consisting of a salt of citrate, maleate, a combination of phosphate and citrate, and arginine; and at least one surfactant.

Abstract: A multi-pole, variable SMD terminal arrangement mountable on a circuit substrate has a stamped metallic element with at least three terminal poles connected with one another by means of a common connecting strip that can be removed after the soldering, the terminal poles having variably formed contact areas on the substrate side that are respectively deflected on one side from the plane of the connecting strip in basically z-shaped fashion, so that the contact areas deflected towards opposite sides form a support base for the terminal arrangement during assembly and soldering. The contact areas comprise end areas that form a contact plane that is coplanar to the substrate during assembly and soldering.

Abstract: The invention concerns pharmaceutical preparations that are stable on storage, which contain at least one diphosphonic acid and/or at least one physiologically acceptable salt of such an acid as the active substance.

Abstract: A thermal fuse includes a leaf spring formed of a narrow sheet metal strip. The leaf spring has ends and at least two contact points at the ends. At least one of the contact points is a soldering point for connection with corresponding circuit contacts of a circuit substrate. The leaf spring has at least one spring arm interconnecting the contact points. The spring arm has a roof-shaped deformation in the vicinity of one contact point. The spring arm has a flat and elongated spring segment with a transition adjoining the deformation and a transition extending to the other contact point. The spring segment is bending resistant in the vicinities of the transitions, for transforming a compressive deformation applied to the roof-shaped deformation into a lateral movement and into an arching of the spring segment, with both ends of the leaf spring attached to the circuit substrate without pretensioning.

Abstract: A method for the production of a radiographic screen comprising the following steps:1) dispersing phosphor particles in an organic liquid in the presence of a charge controlling agent that charges said phosphor particles with a positive or negative net charge,2) arranging said dispersion between a pair of electrodes, wherein one of said electrodes is or carries a conductive support of said radiographic screen,3) applying and maintaining between said electrodes a sufficiently high direct current voltage to deposit charged phosphor particles onto said conductive support, and4) separating said support carrying electrophoretically deposited phosphor particles from said organic liquid,wherein the dispersing of said phosphor particles proceeds by means of an organic surface active compound acting as dispersing agent for said phosphor particles, and said phosphor particles are electrostatically charged through adsorption thereon of ionic components of said organic surface active compound and/or through adsorption of

Abstract: The present invention concerns a process for the production of well-tolerated, preserved injection or infusion solutions containing human protein.

Abstract: A method for the production of a radiographic screen comprising the following steps:1) dispersing phosphor particles in an organic liquid in the presence of a charge controlling agent that charges said phosphor particles with a positive or negative net charge,2) arranging said dispersion between a pair of electrodes, wherein one of said electrodes is or carries a conductive support of said radiographic screen,3) applying and maintaining between said electrodes a sufficiently high direct current voltage to deposit charged phosphor particles onto said conductive support, and4) separating said support carrying electrophoretically deposited phosphor particles from said organic liquid,wherein the dispersing of said phosphor particles proceeds by means of an organic surface active compound acting as dispersing agent for said phosphor particles, and said phosphor particles are electrostatically charged through adsorption thereon of ionic components of said organic surface active compound and/or through adsorption of

Abstract: Colored corundum composite with a matrix of .alpha.-Al.sub.2 O.sub.3, as formed by sol-gel process ending in sintering and size reduction steps with addition of oxide pigments (or precursors of such oxide pigments, formable to the oxide pigment in sinter heating) added to the sol before full gelation thereof.

Abstract: Sintered composite abrasive material useful in abrasives (grinding wheels, abrasive discs and paper, etc.) and cutting tools, comprising an .alpha.-Al.sub.2 O.sub.3 matrix of sub-micron crystallite size made by sol-gel processing with a dispersed phase therein of mechanically resistant material, preferably essentially isotropic grains, added directly to the sol or gel stage of matrix formation.

Abstract: A metal plate is connected over a large area to one side of a glass or ceramic substrate for good heat distribution and removal. The metal plate consists of three layers, namely two outer copper layers and a center Invar layer having the thickness ratio of the layers of approximately 20:60:20. As a result of such a selected thickness ratio, the metal plate exhibits approximately the same coefficient of thermal expansion as the substrate and an inadmissible bending of the substrate or overstressing of the solder or adhesive line between the substrate and metal plate is prevented.

Abstract: The invention relates to a device for supporting the last in a toe lasting machine in which the last, with its sole facing down, is supported on a last support and is held with its heel portion on a heel support carrier which can be adjusted to the length of the last and has an abutment face more or less adapted or adaptable to the shape of the heel portion. To prevent tipping moments from acting on the last during lasting, provision is made for the mounting of the heel support carrier to enable it to pivot relative to the last support about an axis which is vertically below the last support. This pivot axis is substantially parallel to the support plane of the last support for the last and is substantially perpendicular to the longitudinal direction of the heel support carrier holding a last which is clamped for a toe lasting operation.

Abstract: A track recording support for recording devices is suggested with a support (10) made of paper or plastic on which a metallic coating (12) is mounted by means of evaporation and being able to be burned off by means of recording electrodes, in particular an aluminum coating. A lubricant in a finely dispersed form is added to contrast coating (11) for reducing of scratching and grinding traces on the surface of metal coating (12) which reaches metal coating (12) and the freely exposed surface thereof by means of diffusion. Preferably, the lubricant is fed to the contrast substance in a powdery form before the processing of the same. On the one hand, it acts in a physical point of view by a reduction of the slide friction on the surface and, on the other hand, in a chemical point of view in that it substantially prevents the build up of combustion residues from the contrast layer on the recording electrodes.

Abstract: To prevent the formation of scratches, surface discontinuities, slide tracks or striations, for example due to sliding of electrodes (20) over the metal layer (12) of a metalized recording medium, a protective surface coating (13) of low-friction sliding protective material is applied in the form of discontinuous islands over the metal layer (12). The discontinuities permit electrical contact between the electrode (20) and the metal layer (12) although the protective surface coating (13) has insulating properties. The coating (13) may be polymerized hexamethyl-disiloxane, hexafluoropropylene, or Teflon, polymerized, preferably in a hot cathode glow discharge; or a metallic soap. The protective layer is hydrophobic in the form of islands of a thickness of between 10.sup.-9 m to 10.sup.-7 m, preferably about 1 to 2.times.10.sup.-8 m, thus protecting the underlying metal layer (12) against damage by the electrode (20), and attack by moisture or dampness from the ambient atmosphere.

Abstract: To reduce adherence of particles to electrodes and improve the contrast of recording paper, particles of oversized pigments are including in a contrast lacquer or ink layer which have a diameter such that the oversized particles or grains extend out from the lacquer or contrast layer, that is, have a diameter which is greater than the thickness of the ink layer. Suitable particles are carbon black, and calcium carbonate, particularly if darkly colored, present in about 3%-by weight-of the wet content of the lacquer layer which, for example, is a layer of nitrocellulose with finely grained carbon black pigment therein, of a thickness in the order of 1 to 10 .mu.m; the additional oversized pigment granules will have a thickness in the order of about 2 to 20 .mu.m, preferably, on the average, about 5 .mu.m and embedded in lacquer layer of about 2 .mu.m thickness, over which a vapor deposited layer of aluminum of between 0.01 and 0.1 .mu.m is applied. A typical substrate is paper.

Abstract: A shoe lasting machine having a receiving device for a last, a heel band for holding a shoe upper on the last, a first wiper for shearing a heel portion of the shoe upper, a second wiper for wiping a side portion of the shoe upper, and a pincer disposed between the first and second wiper for gripping an edge portion of the upper, wherein the pincer moves over the last in a direction away from the last so that a pull directed away from the last is exerted on the edge portion to avoid forming a pocket in the upper. The pincer includes a pincer part articulated on a pincer base body for gripping the edge portion, wherein the pulling force for each individual pincher part and pincer base body is adjustable. The time point of the pincer opening is adjustable with respect to the movement of the wipers and the heel band. Preferably, the receiving device is arranged to receive the last in an upward-directed position, whereby the pincer is moved upwardly away from the last.

Abstract: Steel, wood and other structural elements and substrates are flameproofed by being coated with a composition comprising at least one metal salt of a phosphonocarboxylic or phosphonophosphonic acid of the formula ##STR1## in which R.sub.1 =a carboxy group, a phosphono group, an alkyl, alkoxy or alkylamino radical optionally substituted one or more times by oxygen and/or nitrogen and containing at least one substituent from the group comprising the substitutents --COOH and --PO.sub.3 H.sub.2, the alkyl group containing from 1 to 12 carbon atoms, preferably from 1 to 4 carbon atoms, and the sum of the number of carboxyl and phosphono groups being from 1 to 8, preferably from 1 to 4; or a hydroxyalkyl or aminoalkyl radical containing from 1 to 12 and preferably from 1 to 4 carbon atoms,R.sub.2 =hydrogen, chlorine, bromine, an alkyl radical with 1 to 12 carbon atoms, preferably with 1 to 4 carbon atoms; a hydroxyl, amino, acylamino such as C.sub.

Abstract: Titanates of zinc and/or alkaline earth metals are produced by simultaneously adding to a suspension of finely divided TiO.sub.2, maintained at a substantially constant pH above about 8, a solution of a salt of zinc and/or alkaline earth metal and alkali to form a hydroxide precipitate. Filtration produces a filter cake mixture of TiO.sub.2 and hydroxide and calcination at above 500.degree. C. produces the desired titanate of narrow particle size distribution and desirable optical properties. Non-simultaneous addition results in a non-filterable material. Zinc, magnesium and/or calcium are preferred and doping elements such as aluminum, phosphorus, boron and/or silicon may also be present.

Abstract: In a two-stage process for producing black iron oxide pigments wherein an iron salt solution is alkalized in a first stage to precipitate about 55 to 70% of the iron, the solution is oxidized to convert the precipitate to goethite, the solution is further alkalized in a second stage to precipitate the balance of the iron, the precipitated iron II hydroxide is allowed to react with goethite to form magnetite, the improvement which comprises effecting the second stage in the presence of an inorganic ionic compound of at least one metal selected from the group consisting of copper, nickel, aluminum, chromium, titanium, zirconium and vanadium in about 0.05 to 5% calculated as metal based on the weight of the final pigment. The resulting pigment is of high color intensity, narrow grain distribution range and pronounced magnetite structure.

Abstract: To prevent the formation of scratches, surface discontinuities, slide tracks or striations, for example due to sliding of electrodes (20) over the metal layer (12) of a metalized recording medium, a protective surface coating (13) of low-friction sliding protective material is applied in the form of discontinuous islands over the metal layer (12). The discontinuities permit electrical contact between the electrode (20) and the metal layer (12) although the protective surface coating (13) has insulating properties. The coating (13) may be polymerized hexamethyl-disiloxane, hexafluoropropylene, or Teflon, polymerized, preferably in hot cathode glow discharge; or a metallic soap. The protective layer is hydrophobic in the form of islands of a thickness of between 10.sup.-9 m to 10.sup.-7 m, preferably about 1 to 2.times.10.sup.-8 m, thus protecting the underlying metal layer (12) against damage by the electrode (20), and attack by moisture or dampness from the ambient atmosphere.