Patents by Inventor Germain Trugnan

Germain Trugnan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11013783
    Abstract: A method for preventing or treating an inflammatory disease, such as inflammatory bowel disease and Crohn disease, is presented. The method includes administering to a patient a polypeptide having the amino acid sequence of SEQ ID NO: 1, a conservative derivative or a fragment thereof, a nucleic acid sequence encoding said polypeptide, a vector comprising said nucleic acid sequence or a host cell that has been transfected, infected or transformed by said nucleic acid sequence and/or by said vector.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: May 25, 2021
    Assignee: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Philippe Langella, Benedicte Pigneur-Arnaud, Jean-Marc Chatel, Elodie Quevrain, Philippe Seksik, Germain Trugnan, Florian Chain, Luis G Bermudez-Humaran, Marie-Anne Maubert, Christophe Michon, Harry Sokol
  • Publication number: 20180085429
    Abstract: A method for preventing or treating an inflammatory disease, such as inflammatory bowel disease and Crohn disease, is presented. The method includes administering to a patient a polypeptide having the amino acid sequence of SEQ ID NO: 1, a conservative derivative or a fragment thereof, a nucleic acid sequence encoding said polypeptide, a vector comprising said nucleic acid sequence or a host cell that has been transfected, infected or transformed by said nucleic acid sequence and/or by said vector.
    Type: Application
    Filed: November 3, 2017
    Publication date: March 29, 2018
    Inventors: Philippe LANGELLA, Benedicte PIGNEUR-ARNAUD, Jean-Marc CHATEL, Elodie QUEVRAIN, Philippe SEKSIK, Germain TRUGNAN, Florian CHAIN, Luis G BERMUDEZ-HUMARAN, Marie-Anne MAUBERT, Christophe MICHON, Harry SOKOL
  • Publication number: 20150335705
    Abstract: A polypeptide including or consisting of the amino acid sequence SEQ ID NO: 1, for use in the treatment or prevention of an inflammatory disease. A nucleic acid sequence encoding the polypeptide, a vector including the nucleic acid and a host cell including the nucleic acid sequence and/or a vector, for use in the treatment or prevention of an inflammatory disease are also described. A pharmaceutical composition including the polypeptide, the nucleic acid sequence, the vector or the host cell and a pharmaceutically acceptable carrier, for the treatment of inflammatory disease are also disclosed.
    Type: Application
    Filed: December 26, 2013
    Publication date: November 26, 2015
    Inventors: Philippe LANGELLA, Benedicte PIGNEUR-ARNAUD, Jean-Marc CHATEL, Elodie QUEVRAIN, Philippe SEKSIK, Germain TRUGNAN, Florian CHAIN, Luis G BERMUDEZ-HUMARAN, Marie-Anne MAUBERT, Christophe MICHON, Harry SOKOL
  • Patent number: 8728743
    Abstract: The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteria, which consists in measuring the average fluorescence intensity variation of HT29-MTX cells incubated in the presence of a lectin coupled with a fluorochrome after being in contact with the supernatant of the strain concerned. Said lactic acid bacteria strains can be used, optionally in the form of their active fraction, for preparing food compositions or medicines or food supplements, modulating glycosylation of glycoproteins of intestinal epithelial cells.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: May 20, 2014
    Assignee: Compagnie Gervais Danone
    Inventors: Jean-Michel Antoine, Miguel Freitas, Chantal Cayuela, Germain Trugnan
  • Publication number: 20060078548
    Abstract: The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteria, which consists in measuring the average fluorescence intensity variation of HT29-MTX cells incubated in the presence of a lectin coupled with a fluorochrome after being in contact with the supernatant of the strain concerned. Said lactic acid bacteria strains can be used, optionally in the form of their active fraction, for preparing food compositions or medicines or food supplements, modulating glycosylation of glycoproteins of intestinal epithelial cells.
    Type: Application
    Filed: November 16, 2005
    Publication date: April 13, 2006
    Inventors: Jean-Michel Antoine, Miguel Freitas, Chantal Cayuela, Germain Trugnan
  • Patent number: 7008785
    Abstract: The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteria, which consists in measuring the average fluorescence intensity variation of HT29-MTX cells incubated in the presence of a lectin coupled with a fluorochrome after being in contact with the supernatant of the strain concerned. Said lactic acid bacteria strains can be used, optionally in the form of their active fraction, for preparing food compositions or medicines or food supplements, modulating glycosylation of glycoproteins of intestinal epithelial cells.
    Type: Grant
    Filed: July 4, 2001
    Date of Patent: March 7, 2006
    Assignee: Compagnie Gervais Danone
    Inventors: Jean-Michel Antoine, Miguel Freitas, Chantal Cayuela, Germain Trugnan
  • Publication number: 20040058409
    Abstract: The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteria, which consists in measuring the average fluorescence intensity variation of HT29-MTX cells incubated in the presence of a lectin coupled with a fluorochrome after being in contact with the supernatant of the strain concerned. Said lactic acid bacteria strains can be used, optionally in the form of their active fraction, for preparing food compositions or medicines or food supplements, modulating glycosylation of glycoproteins of intestinal epithelial cells.
    Type: Application
    Filed: September 11, 2003
    Publication date: March 25, 2004
    Inventors: Jean-Michel Antoine, Miguel Freitas, Chantal Cayuela, Germain Trugnan