Patents by Inventor Germaine Fuh

Germaine Fuh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-HER ANTIBODIES
    Publication number: 20140056899
    Abstract: The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists.
    Type: Application
    Filed: October 29, 2013
    Publication date: February 27, 2014
    Applicant: GENENTECH, INC.
    Inventors: Germaine Fuh, Lauric Haber, Gabriele Schaefer, Mark X. Sliwkowski
  • Anti-VEGF-C Antibodies and Methods Using Same
    Publication number: 20130344072
    Abstract: The invention provides VEGF-C antagonists, such as anti-VEGF-C antibodies, and their use in the prevention and treatment of tumor progression.
    Type: Application
    Filed: June 17, 2013
    Publication date: December 26, 2013
    Applicant: GENENTECH, INC.
    Inventors: Anil D. Bagri, Germaine Fuh, Chingwei V. Lee
  • Multispecific anti-HER antibodies
    Patent number: 8597652
    Abstract: The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: December 3, 2013
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Lauric Haber, Gabriele Schaefer, Mark X. Sliwkowski
  • ANTI-VEGF ANTIBODIES
    Publication number: 20130315918
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Application
    Filed: June 27, 2013
    Publication date: November 28, 2013
    Applicant: Genentech, Inc.
    Inventors: GERMAINE FUH, HANS-PETER GERBER, WEI-CHING LIANG, FREDERIC FELLOUSE, SACHDEV S. SIDHU, CHRISTIAN WIESMANN
  • ANTI-VEGF ANTIBODIES
    Publication number: 20130266581
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Application
    Filed: June 25, 2013
    Publication date: October 10, 2013
    Inventors: Germaine FUH, Hans-Peter Gerber, Wei-Ching Liang, Frederic Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • Anti-VEGF antibodies
    Patent number: 8512699
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: August 20, 2013
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • Anti-VEGF antibodies
    Patent number: 8492527
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: July 23, 2013
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • Anti-VEGF-C antibodies and methods using same
    Patent number: 8486397
    Abstract: The invention provides VEGF-C antagonists, such as anti-VEGF-C antibodies, and their use in the prevention and treatment of tumor progression.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: July 16, 2013
    Assignee: Genentech, Inc.
    Inventors: Anil D. Bagri, Germaine Fuh, Chingwei V. Lee
  • ANTI-VEGF ANTIBODIES
    Publication number: 20120322982
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Application
    Filed: December 22, 2011
    Publication date: December 20, 2012
    Applicant: Genentech, Inc.
    Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • Multispecific antibodies
    Patent number: 8193321
    Abstract: The invention provides multispecific antibodies and methods of making and using such antibodies.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: June 5, 2012
    Assignee: Genentech, Inc.
    Inventors: Jenny M. Bostrom, Germaine Fuh
  • BISPECIFIC ANTI-HER ANTIBODIES
    Publication number: 20120121596
    Abstract: The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists.
    Type: Application
    Filed: March 19, 2010
    Publication date: May 17, 2012
    Inventors: Germaine Fuh, Lauric Haber, Gabriele M. Schaefer, Mark X. Sliwkowski
  • ANTI-VEGF-C ANTIBODIES AND METHODS USING SAME
    Publication number: 20120052566
    Abstract: The invention provides VEGF-C antagonists, such as anti-VEGF-C antibodies, and their use in the prevention and treatment of tumor progression.
    Type: Application
    Filed: September 15, 2010
    Publication date: March 1, 2012
    Inventors: Anil D. Bagri, Germaine Fuh, Chingwei V. Lee
  • Anti-VEGF antibodies
    Patent number: 8101177
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naive libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: January 24, 2012
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • Anti-VEGF antibodies
    Patent number: 8092797
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: January 10, 2012
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • Synthetic antibody phage libraries
    Patent number: 7985840
    Abstract: The invention provides comprising variant amino acids in CDRs of antibody variable domains. These polypeptides provide a source of great sequence diversity that can be used as a source for identifying novel antigen binding polypeptides. The invention also provides these polypeptides as fusion polypeptides to heterologous polypeptides such as at least a portion of phage or viral coat proteins, tags, and linkers. Libraries comprising a plurality of these polypeptides are also provided. In addition, methods of and compositions for generating and using these polypeptides and libraries are provided.
    Type: Grant
    Filed: September 9, 2004
    Date of Patent: July 26, 2011
    Assignee: Genentech, Inc
    Inventors: Germaine Fuh, Sachdev S. Sidhu
  • ANTI-VEGF ANTIBODIES
    Publication number: 20110159009
    Abstract: The invention herein provides isolated antibodies that bind to VEGF. The invention further provides methods of making anti-VEGF antibodies, and polynucleotides encoding anti-VEGF antibodies.
    Type: Application
    Filed: March 3, 2011
    Publication date: June 30, 2011
    Applicant: Genentech, Inc.
    Inventors: Germaine Fuh, Chingwei V. Lee
  • MULTISPECIFIC ANTIBODIES
    Publication number: 20110142852
    Abstract: The invention provides multispecific antibodies and methods of making and using such antibodies.
    Type: Application
    Filed: February 18, 2011
    Publication date: June 16, 2011
    Applicant: Genentech, Inc.
    Inventors: Jenny M. Bostrom, Germaine Fuh
  • ANTI-VEGF-C ANTIBODIES AND METHODS USING SAME
    Publication number: 20110143428
    Abstract: The invention provides VEGF-C antagonists, such as anti-VEGF-C antibodies, and their use in the prevention and treatment of tumor progression.
    Type: Application
    Filed: September 15, 2010
    Publication date: June 16, 2011
    Inventors: Anil D. Bagri, Germaine Fuh, Chingwei V. Lee
  • Anti-VEGF antibodies
    Patent number: 7910098
    Abstract: The invention herein provides isolated antibodies that bind to VEGF. The invention further provides methods of making anti-VEGF antibodies, and polynucleotides encoding anti-VEGF antibodies.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: March 22, 2011
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Chingwei V. Lee
  • ANTI-VEGF ANTIBODIES
    Publication number: 20110020346
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Application
    Filed: July 27, 2010
    Publication date: January 27, 2011
    Applicant: Genentech, Inc.
    Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann