Abstract: The present application relates to benzoheterocyclic derivatives of 2,3-dichlorophenoxyacetic acid, the preparation thereof and pharmaceutical compositions containing them.

Abstract: Aromatic compounds having the following formula are disclosed: ##STR1## in which, A in the heterocyclic group is selected from the group of O and S;R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be identical or different, are selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy;R.sub.5 is selected from the group consisting of hydrogen, lower alkyl and nitro;n is an integer from 1 to 3 andR.sub.6 and R.sub.7 together with the nitrogen atom to which they are attached form a 5- to 7-membered N-heterocyclic saturated group which optionally contain a second hetero atom, which may be O or N and pharmaceutically acceptable acid addition salts of the amino group thereof, said compound being in the form of the E isomer of the oximino group, the Z isomer or mixtures thereof.These novel compounds exhibit a coronary vasodilatory activity and may be used in the treatment of cardiopathies.A method of treating such disorders and a composition useful for treating same are also disclosed.

Abstract: The invention provides certain 4-keto-phenoxyacetic acids and their oximes of the formula: ##STR1## in which A is selected from oxygen and sulphur,Z is selected from oxygen and the group NOH, andX.sub.1 and X.sub.2 are radicals independently selected from hydrogen, halogen and methyl, with the proviso that the benzene nucleus is never substituted by two halogen atoms in ortho-position with respect of one another, and pharmaceutically acceptable alkaline and amine addition salts thereof.

Abstract: Compounds of the general formula I ##STR1## wherein n represents 0, 1 or 2, A represents oxygen or sulphur, Z represents oxygen or hydroxyimino, X represents hydrogen, or halogen, the dotted lines represent bonds which may be unsaturated or saturated, R.sub.1 and R.sub.2 each represent hydrogen or alkyl, and R.sub.3 represents hydrogen, halogen or methyl, and R.sub.4 represents a hydrogen atom, or R.sub.3 and R.sub.4 together with the two carbon atoms to which they are attached represent benzene, and their pharmaceutically acceptable salts are useful in therapy, in particular as uricosuric agents or as diuretic and uricosuric agents.

Abstract: Compounds of the formula I ##STR1## in which R.sub.1 and R.sub.2 each represent a hydrogen atom, a halogen atom, an alkyl group containing 1 to 3 carbon atoms, an alkoxy group containing 1 to 3 carbon atoms or a trifluoromethyl group; and R.sub.3 represents an alkyl group containing 1 to 4 carbon atoms mono- or polyhydroxyl substituted, the alcohol functions being unesterified or esterified by benzoic acid are useful as in therapy as medicaments, in particular as psychotropic and anorexigenic agents.

Abstract: Therapeutic compositions, particularly for treating intestinal disorders, and a method of treating colopathics by administering an effective amount of the compositions are described. The compositions contain a therapeutically effective amount of at least one isomer of the oximino group of the compound having the formula: ##STR1## in which: R is selected from the group consisting of halogen atoms and lower alkoxy groups;n is an integer 2 or 3, andZ.sub.1 and Z.sub.2 are the same or different lower alkyl groups, orNZ.sub.1 Z.sub.2 represents a saturated heterocyclic group which may have a second heteroatom selected from the group consisting of N and O,and the addition salts of the amino group with pharmaceutically acceptable acids,with a physiological acceptable excipient.

Abstract: Bis (2-phenoxyalkane carboxylic acids) and their esters and salts, as well as a method for their preparation. These compounds are useful for the treatment of hyperlipemia and arteriosclerosis.

Abstract: The invention relates to novel thienyl phenyl O-(aminoalkyl)-ketone oximes nd to novel furyl phenyl O-(aminoalkyl)-ketone oximes.These novel compounds exhibit a coronary vasodilatatory activity and may be used in the treatment of cardiopathies.The invention also relates to a process for preparing these novel compounds by reaction of a diaromatic ketone with a hydroxylamine.

Abstract: The present application relates to phenoxy-acetic derivatives, the preparation thereof and pharmaceutical compositions containing them.

Abstract: The invention relates to new derivatives of 3-oxo-2,3-dihydro-1,4-benzoxazine corresponding to the general formula ##SPC1##In whichR.sub.1 is selected from the group consisting of the hydrogen atom and a lower alkyl group;R.sub.2, r.sub.3 and R.sub.4 which are identical or different, are selected from the group consisting of the hydrogen atom, a halogen atom, a nitro group, a lower alkyl group, a lower alkoxy group and R.sub.4 may be an allyl group;R.sub.5 is selected from the group consisting of the hydrogen atom and an acyl group, preferably acetyl. These derivatives can be used for therapeutic purposes, more especially as analgesics and anti-oedematous agents.