Patents by Inventor Germano Coppi

Germano Coppi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby
    Patent number: 9150590
    Abstract: Process for the preparation of rifaximin, pseudo-crystalline rifaximin and a new pseudo-crystalline form of rifaximin with fewer impurities obtained thereby.
    Type: Grant
    Filed: May 21, 2012
    Date of Patent: October 6, 2015
    Assignee: Friulchem Spa
    Inventors: Disma Mazzola, Silvia Moiana, Germano Coppi
  • New Process for the Synthesis of Rifaximin and a New Pseudo-Crystalline Form of Rifaximin Obtained Thereby
    Publication number: 20140155422
    Abstract: Process for the preparation of rifaximin, pseudo-crystalline rifaximin and a new pseudo-crystalline form of rifaximin with fewer impurities obtained thereby.
    Type: Application
    Filed: May 21, 2012
    Publication date: June 5, 2014
    Applicant: FRIULCHEM SPA
    Inventors: Disma Mazzola, Silvia Moiana, Germano Coppi
  • Oral, cutaneous and intravaginal pharmaceutical compositions in the form of foam
    Patent number: 5369131
    Abstract: A liquid pharmaceutical composition which can be administered as a foam by means of suitable supplying devices, without necessity of gas propeller, said composition consisting of:a) one or more natural or synthetic ionic or non ionic, acid, basic or neutral surfactants;b) a solvent or a solvent mixture;c) an active ingredient or a combination of active ingredients;d) optionally mucoadhesive or thermosetting polymers;e) optional adjuvants or excipients.
    Type: Grant
    Filed: May 20, 1993
    Date of Patent: November 29, 1994
    Assignee: Poli Industria Chimica S.p.A.
    Inventors: Stefano Poli, Germano Coppi, Cesare Busetti
  • N-(5-thioxo-L-prolyl)-L-cysteine, derivatives thereof, processes for the preparation thereof and pharmaceutical compositions containing them
    Patent number: 5254579
    Abstract: N-(5-thioxo-L-prolyl)-L-cysteine and derivatives thereof, having interesting mucolytic-expectorant, antioxidant (radical-scavenger), antielastase, antiemphysema, immunostimulating and hepatoprotective activities and a low toxicity are described, as well as processes for the preparation thereof and pharmaceutical formulations for the use in therapy.
    Type: Grant
    Filed: May 8, 1992
    Date of Patent: October 19, 1993
    Assignee: Poli Industria Chimica S.p.A.
    Inventors: Stefano Poli, Germano Coppi, Giovanni Signorelli
  • 3-L-(5-thioxo-L-prolyl)thiazolidine-4-carboxylic acid and derivatives therefrom, processes for the preparation thereof and pharmaceutical compositions containing them
    Patent number: 5212160
    Abstract: 3-L-(5-thioxo-L-prolyl)thiazolidine-4-carboxylic acid and the derivatives thereof have valuable immunostimulating, antioxidant, antiradical and antiageing properties. They are prepared by thionating the corresponding 3-L-pyroglutamyl-L-thiazolidine-4-carboxylic acid derivatives or by condensing 5-thioxo-L-proline with the corresponding L-thiazolidine-4-carboxylic acid derivatives.
    Type: Grant
    Filed: January 16, 1991
    Date of Patent: May 18, 1993
    Assignee: Poli Industria Chimica S.p.A.
    Inventors: Stefano Poli, Lucio Del Corona, Germano Coppi
  • Derivatives of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it
    Patent number: 5066644
    Abstract: Ester or amide derivatives of 3-pyroglutamylthiazolidine-4-carboxylic acid exhibit interesting immunostimulating, antitoxic, antiinflammatory, antioxidental, antiageing properties.
    Type: Grant
    Filed: February 9, 1990
    Date of Patent: November 19, 1991
    Assignee: Poli Industria Chimica S.p.A.
    Inventors: Stefano Poli, Germano Coppi, Lucio Del Corona
  • N-cycloalkylaminoethylbenzamide derivatives, their synthesis and pharmaceutical preparations
    Patent number: 5010108
    Abstract: New N-(2-cycloalkylamino)ethyl-substituted benzamides having a powerful stimulating activity on gastric motility and with a low central anti-dopaminergic activity are described. The synthesis and the pharmaceutical preparation for therapeutical use are also described.
    Type: Grant
    Filed: March 15, 1989
    Date of Patent: April 23, 1991
    Assignee: Poli Industria Chimica S.p.A.
    Inventors: Stefano Poli, Germano Coppi, Lucio Del Corona
  • Diacetylrhein salts and their therapeutical use in the treatment of arthrosis
    Patent number: 4950687
    Abstract: A therapeutic treatment for the athrosis diseases comprising administering by intraarticular route from 1 to 5 ml of an aqueous solution containing from 10 to 50 mg of a diacetyl rhein salt having formula (I): ##STR1## wherein M represents an alkali or an earth alkali metal or the residue of an organic base.The diacetyl rhein salts administered by intraarticular route exhibit higher pharmacological activity than the corresponding diacetylrhein administered orally.
    Type: Grant
    Filed: July 17, 1989
    Date of Patent: August 21, 1990
    Assignee: Proter S.p.A.
    Inventors: Leone Dall'Asta, Germano Coppi, Mario Ercole Scevola
  • Galenic formulations for oral use of rhein derivatives with delayed release for therapeutical use
    Patent number: 4861599
    Abstract: Several methods are disclosed for the preparation of oral pharmaceutical forms with delayed release of rhein and its derivatives. The pharmaceutically active ingredient is provided in the form of granules, coated with at least one of polyvinylpyrrolidone, shellac and hydroxypropylmethyl cellulose. The desired effect of the coating is to slow release of the pharmaceutically active ingredient by resisting gastric juices in the stomach, but gradually dissolving in the intestines.
    Type: Grant
    Filed: September 30, 1987
    Date of Patent: August 29, 1989
    Assignee: Proter S.p.A.
    Inventors: Vanna Springolo, Germano Coppi, Mario E. Scevola