Patents by Inventor Gernot Köhler

Gernot Köhler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230066416
    Abstract: A test kit for detecting organophosphate compounds, includes a support apparatus, a sampling device, a buffer solution in a sample tube, and an acetylcholinesterase as the first active component and a mixture of 5,5?-dithiobis(2-nitrobenzoic acid) (DTNB) and acetylthiocholine. The sampling device is packaged in a sample tube, where the first active component is applied in a first reagent cap and the second active component is applied in a second reagent cap, and the first and second reagent caps each seal a sample tube. The support apparatus has at least four fixing devices for receiving the sample tubes. The sample tubes are fixed parallel to the upper side of the support apparatus, and the support apparatus has at least two receiving devices for receiving the first and second reagent caps and one receiving device for vertically receiving a sample tube.
    Type: Application
    Filed: August 23, 2022
    Publication date: March 2, 2023
    Inventors: Gernot Köhler, Frauke Weiss
  • Patent number: 9603354
    Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: March 28, 2017
    Assignee: DR. FRANZ KOEHLER CHEMIE GMBH
    Inventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns
  • Publication number: 20110300237
    Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.
    Type: Application
    Filed: June 2, 2011
    Publication date: December 8, 2011
    Inventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns
  • Patent number: 7977383
    Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: July 12, 2011
    Assignee: Dr. Franz Koehler Chemie GmbH
    Inventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns
  • Patent number: 7737229
    Abstract: The invention relates to a process for the continuous preparation of ethylene homopolymers or copolymers in the presence of free-radical polymerization initiators and, if desired, molecular weight regulators at from 120° C. to 350° C. and pressures in the range from 100 to 4000 bar, in which the polymer is separated from unpolymerized ethylene in a high-pressure stage at a pressure of from 100 to 500 bar and at least one low-pressure stage at a pressure of from 1 to 100 bar and the ethylene separated off in the high-pressure stage is separated from remaining monomeric, oligomeric and/or polymeric constituents and recirculated to the inlet of the tube reactor in a high-pressure circuit and the ethylene separated off in the low-pressure stage is separated from remaining monomeric, oligomeric and/or polymeric constituents and recirculated to the inlet of the tube reactor in a low-pressure circuit. The initiator is used as a solution in an isoparaffinic solvent having a boiling point of not more than 160° C.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: June 15, 2010
    Assignee: Basell Polyolefine GmbH
    Inventors: Andrei Gonioukh, Gernot Köhler, Theo Teuber, Thomas Dröge
  • Patent number: 7709584
    Abstract: A process for preparing ethylene homopolymers and copolymers in a tubular reactor having two or more polymerization zones at temperatures of between 150° C. and 350° C. and pressures in the range from 500 to 5000 bar, using oxygen as initiator, which comprises using, as molar mass regulator, one or more aliphatic ketones of the formula I, where the variable R1 is a C1-C6-alkyl or C3-C12-cycloalkyl, ethylene homopolymers and copolymers obtainable therefrom and their user for producing injection-molded products in the cosmetics, medical and food sectors are described.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: May 4, 2010
    Assignee: Basell Polyolefine GmbH
    Inventors: Frank-Olaf Mähling, Andreas Deckers, Gernot Köhler, Axel Schmitz, Lars Wittkowski, Michael Hoppach
  • Patent number: 6887955
    Abstract: In a process for the polymerization of ethylene and optionally further monomers in a high-pressure reactor at from 120 to 350° C. and pressures of from 1000 to 4000 bar, hydrogen is intermittently introduced into the reactor.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: May 3, 2005
    Assignee: Basell Polyolefine GmbH
    Inventors: Andreas Deckers, Frank Olaf Maehling, Georg Groos, Wilhelm Weber, Gernot Koehler
  • Patent number: 6849698
    Abstract: In a process for polymerizing ethylene and, if desired, further monomers in a high-pressure reactor at from 140 to 320° C. and pressures of from 1000 to 4000 bar, but in any case under pressure and temperature conditions under which water displays supercritical behavior, water is introduced continuously or intermittently into the reactor.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: February 1, 2005
    Assignee: Basell Polyolefine GmbH
    Inventors: Eckhard Häffner, Dieter Littmann, Frank-Olaf Mähling, Gernot Köhler
  • Patent number: 6844408
    Abstract: Ethylene homopolymers and copolymers are prepared in a tube reactor at from 160° C. to 350° C. and pressures in the range from 500 to 5000 bar, with or without use of molar mass regulators, using a peroxide mixture comprising from 1 to 95 mol %, based on the total amount of the peroxide mixture, of at least one cyclic peroxide of the formula I, where the radicals R are identical or different and are selected from among alkyl groups and aryl groups, as polymerization initiator.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: January 18, 2005
    Assignee: Basell Polyolefine GmbH
    Inventors: Andrei Gonioukh, Lars Wittkowski, Thomas Dröge, Ernst Fischer, Roger Klimesch, Philipp Rosendorfer, Gernot Köhler, Dieter Littmann
  • Publication number: 20040181015
    Abstract: In a process for the polymerization of ethylene and optionally further monomers in a high-pressure reactor at from 120 to 350° C. and pressures of from 1000 to 4000 bar, hydrogen is intermittently introduced into the reactor.
    Type: Application
    Filed: February 11, 2004
    Publication date: September 16, 2004
    Inventors: Andreas Deckers, Frank Olaf, Georg Groos, Wilhelm Weber, Gernot Koehler
  • Publication number: 20030215781
    Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.
    Type: Application
    Filed: May 16, 2003
    Publication date: November 20, 2003
    Inventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns
  • Patent number: 6245864
    Abstract: A copolymer of (a) from 96 to 99.6% molar of ethylene and (b) from 0.4 to 4% molar of a C3-C6-alkenoic acid or an ester thereof having not more than 14 carbon atoms or a mixture of these monomers, which copolymer may be prepared by polymerization in a continuously operated tubular reactor under a pressure of from 500 to 5,000 bar and at elevated temperature in the presence of free-radical initiators by feeding a mixture of the said reactants to the inlet port of the reactor only, restricting the temperature in a first reaction zone to approximately 240° C. and, after the temperature has dropped by from 5°to 20° C., metering further initiator to the beginning of a second reaction zone and completing the reaction at a temperature of up to 300° C.
    Type: Grant
    Filed: March 16, 1994
    Date of Patent: June 12, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Norbert Hasenbein, Thomas Muehlenbernd, Gernot Koehler
  • Patent number: 5753708
    Abstract: The invention describes new salts and amides of 4-hydroxybutyric acid with the aim of improving the pharmacological and therapeutic properties of 4-hydroxybutyric acid.
    Type: Grant
    Filed: April 23, 1996
    Date of Patent: May 19, 1998
    Inventors: Gernot Koehler, Anita Koehler
  • Patent number: 5380937
    Abstract: The invention describes new salts and amides of 4-hydroxybutyric acid with the aim of improving the pharmacological and therapeutic properties of 4-hydroxybutyric acid.
    Type: Grant
    Filed: December 29, 1992
    Date of Patent: January 10, 1995
    Inventors: Gernot Koehler, Anita Koehler
  • Patent number: 5306791
    Abstract: Novel ethylene homopolymers and ethylene copolymers which are suitable for film production and have a density from 925 to 940 kg /m.sup.3, a melt flow index (MFI) of <1 g/10 min at 190.degree. C. and at an applied force of 2.16 kp can be prepared by free radical polymerization of the monomers at from 500 to 5000 bar and reaction temperatures T of from 40.degree. to 320.degree. C. by means of an initiator with virtually complete exclusion of oxygen in at least n=3 polymerization stages. In the first stage, the total amount or the predominant part of the monomers is subjected to the polymerization by means of part of the required initiator until the polymerization virtually comes to a stop. A further part of the initiator and, if required, of the monomers is then added to the mixture cooled to 20.degree.-60.degree. C. This process is repeated in the subsequent stages until the n th stage, at least the initiators used in the n th stage having a half-life temperature of from 90.degree. to 260.degree. C.
    Type: Grant
    Filed: May 6, 1993
    Date of Patent: April 26, 1994
    Assignee: BASF Aktiengesellschaft
    Inventors: Thomas Muehlenbernd, Roger Klimesch, Gernot Koehler, Ernst Fischer
  • Patent number: 5189113
    Abstract: Ionically crosslinked ethylene copolymers are prepared by reacting the corresponding ethylene copolymer in a mixing zone of a twin-screw extruder with a solid metal compound and subsequently pumping in water, and are used as adhesion promoters, laminating films, injection molded articles or cable sheathing.
    Type: Grant
    Filed: June 14, 1989
    Date of Patent: February 23, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Thomas Muehlenbernd, Norbert Hasenbein, Gernot Koehler, Lothar Schlemmer
  • Patent number: 5174867
    Abstract: Electrically conductive, finely divided pyrrole polymers are prepared by a process in which a pyrrole is polymerized in the presence of a carrier and are used for the production of shaped articles and coatings.
    Type: Grant
    Filed: February 28, 1984
    Date of Patent: December 29, 1992
    Inventors: Herbert Naarmann, Walter Heckmann, Gernot Koehler, Petr Simak
  • Patent number: 5173275
    Abstract: A method of removing or of accumulating heavy metal ions from an aqueous solution by contacting the latter with an ethylene copolymer, in which a copolymer of ethylene with (meth)acrylic acid and a (meth)acrylate is used, in which the carboxyl groups may be neutralized by metal ions to an extent of 100% or less.
    Type: Grant
    Filed: June 12, 1991
    Date of Patent: December 22, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Gernot Koehler, Roger Klimesch
  • Patent number: 5100978
    Abstract: Polyethylene and copolymers of predominant amounts of ethylene and minor amounts of comonomers which are polymerizable with ethylene are obtainable by free radical polymerization of the monomers under from 1,500 to 5,000 bar and at from 40.degree. to 250.degree. C. by means of an initiator with virtually complete exclusion of oxygen in not less than n=3 polymerization stages, by a method in which, in the first stage, the total amount of the predominant part of the monomers are subjected to polymerization using some of the initiator required, until said polymerization comes virtually to a stop, thereafter a further part of the initiator and, if required, of the monomers are added to the mixture, which has been cooled by 20.degree.-60.degree. C., and this process is repeated in the subsequent stages until the n th stage, with the proviso that the initiators used in the (n-1) th stage have a half-life temperature of from 80.degree. to 160.degree. C.
    Type: Grant
    Filed: April 12, 1990
    Date of Patent: March 31, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Norbert Hasenbein, Wolfgang Ball, Juergen Schmidt-Theummes, Gernot Koehler
  • Patent number: 5028265
    Abstract: Aqueous dispersions of ethylene copolymer waxes, which dispersions are free-flowing at room temperature, contain a mixture of an ethylene copolymer wax having a high acid number and an ehtylene copolymer wax having a low acid number.The novel mixtures are particularly suitable as surface preservatives, as components in floor care agents or as sizes in textile finishing.
    Type: Grant
    Filed: June 21, 1990
    Date of Patent: July 2, 1991
    Assignee: BASF Aktiengesellschaft
    Inventors: Juergen Schmidt-Thuemmes, Gernot Koehler