Patents by Inventor Gernot Köhler
Gernot Köhler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230066416Abstract: A test kit for detecting organophosphate compounds, includes a support apparatus, a sampling device, a buffer solution in a sample tube, and an acetylcholinesterase as the first active component and a mixture of 5,5?-dithiobis(2-nitrobenzoic acid) (DTNB) and acetylthiocholine. The sampling device is packaged in a sample tube, where the first active component is applied in a first reagent cap and the second active component is applied in a second reagent cap, and the first and second reagent caps each seal a sample tube. The support apparatus has at least four fixing devices for receiving the sample tubes. The sample tubes are fixed parallel to the upper side of the support apparatus, and the support apparatus has at least two receiving devices for receiving the first and second reagent caps and one receiving device for vertically receiving a sample tube.Type: ApplicationFiled: August 23, 2022Publication date: March 2, 2023Inventors: Gernot Köhler, Frauke Weiss
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Patent number: 9603354Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.Type: GrantFiled: June 2, 2011Date of Patent: March 28, 2017Assignee: DR. FRANZ KOEHLER CHEMIE GMBHInventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns
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Publication number: 20110300237Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.Type: ApplicationFiled: June 2, 2011Publication date: December 8, 2011Inventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns
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Patent number: 7977383Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.Type: GrantFiled: May 16, 2003Date of Patent: July 12, 2011Assignee: Dr. Franz Koehler Chemie GmbHInventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns
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Patent number: 7737229Abstract: The invention relates to a process for the continuous preparation of ethylene homopolymers or copolymers in the presence of free-radical polymerization initiators and, if desired, molecular weight regulators at from 120° C. to 350° C. and pressures in the range from 100 to 4000 bar, in which the polymer is separated from unpolymerized ethylene in a high-pressure stage at a pressure of from 100 to 500 bar and at least one low-pressure stage at a pressure of from 1 to 100 bar and the ethylene separated off in the high-pressure stage is separated from remaining monomeric, oligomeric and/or polymeric constituents and recirculated to the inlet of the tube reactor in a high-pressure circuit and the ethylene separated off in the low-pressure stage is separated from remaining monomeric, oligomeric and/or polymeric constituents and recirculated to the inlet of the tube reactor in a low-pressure circuit. The initiator is used as a solution in an isoparaffinic solvent having a boiling point of not more than 160° C.Type: GrantFiled: October 27, 2004Date of Patent: June 15, 2010Assignee: Basell Polyolefine GmbHInventors: Andrei Gonioukh, Gernot Köhler, Theo Teuber, Thomas Dröge
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Patent number: 7709584Abstract: A process for preparing ethylene homopolymers and copolymers in a tubular reactor having two or more polymerization zones at temperatures of between 150° C. and 350° C. and pressures in the range from 500 to 5000 bar, using oxygen as initiator, which comprises using, as molar mass regulator, one or more aliphatic ketones of the formula I, where the variable R1 is a C1-C6-alkyl or C3-C12-cycloalkyl, ethylene homopolymers and copolymers obtainable therefrom and their user for producing injection-molded products in the cosmetics, medical and food sectors are described.Type: GrantFiled: December 12, 2001Date of Patent: May 4, 2010Assignee: Basell Polyolefine GmbHInventors: Frank-Olaf Mähling, Andreas Deckers, Gernot Köhler, Axel Schmitz, Lars Wittkowski, Michael Hoppach
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Patent number: 6887955Abstract: In a process for the polymerization of ethylene and optionally further monomers in a high-pressure reactor at from 120 to 350° C. and pressures of from 1000 to 4000 bar, hydrogen is intermittently introduced into the reactor.Type: GrantFiled: August 13, 2002Date of Patent: May 3, 2005Assignee: Basell Polyolefine GmbHInventors: Andreas Deckers, Frank Olaf Maehling, Georg Groos, Wilhelm Weber, Gernot Koehler
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Patent number: 6849698Abstract: In a process for polymerizing ethylene and, if desired, further monomers in a high-pressure reactor at from 140 to 320° C. and pressures of from 1000 to 4000 bar, but in any case under pressure and temperature conditions under which water displays supercritical behavior, water is introduced continuously or intermittently into the reactor.Type: GrantFiled: May 25, 2001Date of Patent: February 1, 2005Assignee: Basell Polyolefine GmbHInventors: Eckhard Häffner, Dieter Littmann, Frank-Olaf Mähling, Gernot Köhler
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Patent number: 6844408Abstract: Ethylene homopolymers and copolymers are prepared in a tube reactor at from 160° C. to 350° C. and pressures in the range from 500 to 5000 bar, with or without use of molar mass regulators, using a peroxide mixture comprising from 1 to 95 mol %, based on the total amount of the peroxide mixture, of at least one cyclic peroxide of the formula I, where the radicals R are identical or different and are selected from among alkyl groups and aryl groups, as polymerization initiator.Type: GrantFiled: March 13, 2001Date of Patent: January 18, 2005Assignee: Basell Polyolefine GmbHInventors: Andrei Gonioukh, Lars Wittkowski, Thomas Dröge, Ernst Fischer, Roger Klimesch, Philipp Rosendorfer, Gernot Köhler, Dieter Littmann
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Publication number: 20040181015Abstract: In a process for the polymerization of ethylene and optionally further monomers in a high-pressure reactor at from 120 to 350° C. and pressures of from 1000 to 4000 bar, hydrogen is intermittently introduced into the reactor.Type: ApplicationFiled: February 11, 2004Publication date: September 16, 2004Inventors: Andreas Deckers, Frank Olaf, Georg Groos, Wilhelm Weber, Gernot Koehler
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Publication number: 20030215781Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.Type: ApplicationFiled: May 16, 2003Publication date: November 20, 2003Inventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns
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Patent number: 6245864Abstract: A copolymer of (a) from 96 to 99.6% molar of ethylene and (b) from 0.4 to 4% molar of a C3-C6-alkenoic acid or an ester thereof having not more than 14 carbon atoms or a mixture of these monomers, which copolymer may be prepared by polymerization in a continuously operated tubular reactor under a pressure of from 500 to 5,000 bar and at elevated temperature in the presence of free-radical initiators by feeding a mixture of the said reactants to the inlet port of the reactor only, restricting the temperature in a first reaction zone to approximately 240° C. and, after the temperature has dropped by from 5°to 20° C., metering further initiator to the beginning of a second reaction zone and completing the reaction at a temperature of up to 300° C.Type: GrantFiled: March 16, 1994Date of Patent: June 12, 2001Assignee: BASF AktiengesellschaftInventors: Norbert Hasenbein, Thomas Muehlenbernd, Gernot Koehler
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Patent number: 5753708Abstract: The invention describes new salts and amides of 4-hydroxybutyric acid with the aim of improving the pharmacological and therapeutic properties of 4-hydroxybutyric acid.Type: GrantFiled: April 23, 1996Date of Patent: May 19, 1998Inventors: Gernot Koehler, Anita Koehler
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Patent number: 5380937Abstract: The invention describes new salts and amides of 4-hydroxybutyric acid with the aim of improving the pharmacological and therapeutic properties of 4-hydroxybutyric acid.Type: GrantFiled: December 29, 1992Date of Patent: January 10, 1995Inventors: Gernot Koehler, Anita Koehler
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Patent number: 5306791Abstract: Novel ethylene homopolymers and ethylene copolymers which are suitable for film production and have a density from 925 to 940 kg /m.sup.3, a melt flow index (MFI) of <1 g/10 min at 190.degree. C. and at an applied force of 2.16 kp can be prepared by free radical polymerization of the monomers at from 500 to 5000 bar and reaction temperatures T of from 40.degree. to 320.degree. C. by means of an initiator with virtually complete exclusion of oxygen in at least n=3 polymerization stages. In the first stage, the total amount or the predominant part of the monomers is subjected to the polymerization by means of part of the required initiator until the polymerization virtually comes to a stop. A further part of the initiator and, if required, of the monomers is then added to the mixture cooled to 20.degree.-60.degree. C. This process is repeated in the subsequent stages until the n th stage, at least the initiators used in the n th stage having a half-life temperature of from 90.degree. to 260.degree. C.Type: GrantFiled: May 6, 1993Date of Patent: April 26, 1994Assignee: BASF AktiengesellschaftInventors: Thomas Muehlenbernd, Roger Klimesch, Gernot Koehler, Ernst Fischer
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Patent number: 5189113Abstract: Ionically crosslinked ethylene copolymers are prepared by reacting the corresponding ethylene copolymer in a mixing zone of a twin-screw extruder with a solid metal compound and subsequently pumping in water, and are used as adhesion promoters, laminating films, injection molded articles or cable sheathing.Type: GrantFiled: June 14, 1989Date of Patent: February 23, 1993Assignee: BASF AktiengesellschaftInventors: Thomas Muehlenbernd, Norbert Hasenbein, Gernot Koehler, Lothar Schlemmer
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Patent number: 5174867Abstract: Electrically conductive, finely divided pyrrole polymers are prepared by a process in which a pyrrole is polymerized in the presence of a carrier and are used for the production of shaped articles and coatings.Type: GrantFiled: February 28, 1984Date of Patent: December 29, 1992Inventors: Herbert Naarmann, Walter Heckmann, Gernot Koehler, Petr Simak
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Patent number: 5173275Abstract: A method of removing or of accumulating heavy metal ions from an aqueous solution by contacting the latter with an ethylene copolymer, in which a copolymer of ethylene with (meth)acrylic acid and a (meth)acrylate is used, in which the carboxyl groups may be neutralized by metal ions to an extent of 100% or less.Type: GrantFiled: June 12, 1991Date of Patent: December 22, 1992Assignee: BASF AktiengesellschaftInventors: Gernot Koehler, Roger Klimesch
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Patent number: 5100978Abstract: Polyethylene and copolymers of predominant amounts of ethylene and minor amounts of comonomers which are polymerizable with ethylene are obtainable by free radical polymerization of the monomers under from 1,500 to 5,000 bar and at from 40.degree. to 250.degree. C. by means of an initiator with virtually complete exclusion of oxygen in not less than n=3 polymerization stages, by a method in which, in the first stage, the total amount of the predominant part of the monomers are subjected to polymerization using some of the initiator required, until said polymerization comes virtually to a stop, thereafter a further part of the initiator and, if required, of the monomers are added to the mixture, which has been cooled by 20.degree.-60.degree. C., and this process is repeated in the subsequent stages until the n th stage, with the proviso that the initiators used in the (n-1) th stage have a half-life temperature of from 80.degree. to 160.degree. C.Type: GrantFiled: April 12, 1990Date of Patent: March 31, 1992Assignee: BASF AktiengesellschaftInventors: Norbert Hasenbein, Wolfgang Ball, Juergen Schmidt-Theummes, Gernot Koehler
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Patent number: 5028265Abstract: Aqueous dispersions of ethylene copolymer waxes, which dispersions are free-flowing at room temperature, contain a mixture of an ethylene copolymer wax having a high acid number and an ehtylene copolymer wax having a low acid number.The novel mixtures are particularly suitable as surface preservatives, as components in floor care agents or as sizes in textile finishing.Type: GrantFiled: June 21, 1990Date of Patent: July 2, 1991Assignee: BASF AktiengesellschaftInventors: Juergen Schmidt-Thuemmes, Gernot Koehler