Patents by Inventor Gernot Langer

Gernot Langer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230112499
    Abstract: The present invention covers furoindazole compounds of general formula (I): in which (I) are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of autoimmune diseases such as multiple sclerosis, psoriasis, psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, primary and secondary autoimmune uveitis, inflammatory disorders like endometriosis, inflammatory eye diseases, inflammatory kidney diseases, inflammatory liver diseases like non-alcoholic, alcoholic- and toxic fatty liver diseases, lung diseases like asthma, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease and metabolic and metabolic-endocrine disorders like metabolic syndrome, insulin resistance, diabetes mellitus type I and type II, and po
    Type: Application
    Filed: December 14, 2020
    Publication date: April 13, 2023
    Applicant: Bayer Aktiengesellschaft
    Inventors: Olaf PANKNIN, Frank SACHER, Nicole SCHMIDT, Gernot LANGER, Katrin NOWAK-REPPEL, Reinhard NUBBEMEYER, Sabine PILARI, Antje ROTTMANN, Hideki MIYATAKE ONDOZABAL, Holger SIEBENEICHER, Antonius TER LAAK, Hana CERNECKA
  • Publication number: 20210401823
    Abstract: The present invention relates to an antagonist or inhibitor of G protein-coupled receptor 84 (GPR84) for use in the treatment and/or prevention of a patient suffering from, at risk of developing, and/or being diagnosed for endometriosis, as well as methods of screening for such antagonist or inhibitor as well as methods for diagnosis.
    Type: Application
    Filed: May 15, 2018
    Publication date: December 30, 2021
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Frank SACHER, Maik OBENDORF, Gernot LANGER, Fernando MARTINEZ ESTRADA, Udo OPPERMANN, Catherine SHANG
  • Patent number: 10730856
    Abstract: The present invention relates to novel benzimidazole derivatives of the general formula (I), to processes for their preparation and to their use for preparing pharmaceutical compositions for the treatment of disorders and indications associated with the EP4 receptor.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: August 4, 2020
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Olaf Peters, Nico Bräuer, Ulrich Bothe, Marcus Koppitz, Jens Nagel, Gernot Langer
  • Patent number: 9708311
    Abstract: The present invention relates to novel benzimidazole derivatives of the general formula processes for their preparation and their use for the production of pharmaceutical compositions for the treatment of diseases and indications that are connected with the receptor EP4.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: July 18, 2017
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Olaf Peters, Nico Bräuer, Thorsten Blume, Antonius Ter Laak, Ludwig Zorn, Jens Nagel, Stefan Kaulfuss, Gernot Langer, Joachim Kuhnke
  • Patent number: 9691385
    Abstract: According to some aspects, a method of associating dictation with an electronic record in a system having a dictation system comprising a dictation application for capture of speech input and a separate electronic records system for managing electronic records is provided. The method comprises receiving, by the dictation application, speech input from a user corresponding to a dictation to be associated with an electronic record of the electronic records system, obtaining, by the dictation application, a job identifier associated with the dictation, providing, by the dictation application, the job identifier and audio data based on the speech input for transcription, obtaining, by the dictation application, a dictation marker comprising the job identifier and one or more delimiters, and causing the dictation marker to be inserted into the electronic record.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: June 27, 2017
    Assignee: Nuance Communications, Inc.
    Inventors: Andreas Neubacher, Mehmet Mert Oez, Matthias Helletzgruber, Gernot Langer
  • Publication number: 20160214977
    Abstract: The present invention relates to novel benzimidazole derivatives of the general formula (I), processes for their preparation and their use for the production of pharmaceutical compositions for the treatment of diseases and indications that are connected with the receptor EP4.
    Type: Application
    Filed: December 3, 2013
    Publication date: July 28, 2016
    Inventors: Olaf PETERS, Nico BRÄUER, Thorsten BLUME, Antonius TER LAAK, Ludwig ZORN, Jens NAGEL, Stefan KAULFUSS, Gernot LANGER, Joachim KUHNKE
  • Publication number: 20160052936
    Abstract: Spiroindoline derivatives, processes for their preparation and pharmaceutical compositions thereof, their use for the treatment of diseases, and their use for the manufacture of medicaments for the treatment of diseases, especially sex-hormone-related diseases in both men and women, in particularly those selected from the group of endometriosis, uterine leiomyoma (fibroids), polycystic ovarian disease, menorrhagia, dysmenorrhea, hirsutism, precocious puberty, gonadal steroid-dependent neoplasia such as cancers of the prostate, breast and ovary, gonadotrope pituitary adenomas, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hypertrophy, contraception, infertility and assisted reproductive therapy such as in vitro fertilization. The present application relates in particular to spiroindoline derivatives as gonadotropin-releasing hormone (GnRH) receptor antagonists.
    Type: Application
    Filed: April 8, 2014
    Publication date: February 25, 2016
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Olaf PANKNIN, Sven RING, Stefan BÄURLE, Andrea WAGENFELD, Reinhard NUBBEMEYER, Katrin NOWAK-REPPEL, Gernot LANGER
  • Publication number: 20150371637
    Abstract: According to some aspects, a method of associating dictation with an electronic record in a system having a dictation system comprising a dictation application for capture of speech input and a separate electronic records system for managing electronic records is provided. The method comprises receiving, by the dictation application, speech input from a user corresponding to a dictation to be associated with an electronic record of the electronic records system, obtaining, by the dictation application, a job identifier associated with the dictation, providing, by the dictation application, the job identifier and audio data based on the speech input for transcription, obtaining, by the dictation application, a dictation marker comprising the job identifier and one or more delimiters, and causing the dictation marker to be inserted into the electronic record.
    Type: Application
    Filed: June 19, 2014
    Publication date: December 24, 2015
    Inventors: Andreas Neubacher, Mehmet Mert Öz, Matthias Helletzgruber, Gernot Langer
  • Publication number: 20100029598
    Abstract: The present invention relates to extended benzamide derivatives of the general formula I, to processes for preparation thereof and to use thereof for production of pharmaceutical compositions for treatment of disorders and indications associated with the EP2 receptor.
    Type: Application
    Filed: July 24, 2009
    Publication date: February 4, 2010
    Applicant: Bayer Schering Pharma AG
    Inventors: Marcus Kopitz, Bernhard Lindenthal, Antonius Ter Laak, Tim Wintermantel, Olaf Peters, Gernot Langer, Nico Braeuer, Bernd Buchmann
  • Publication number: 20100029599
    Abstract: The present invention relates to indolylamide derivatives of the general formula (I), to processes for preparation thereof and to use thereof for production of pharmaceutical compositions for treatment of disorders and indications associated with the EP2 receptor.
    Type: Application
    Filed: July 29, 2009
    Publication date: February 4, 2010
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Marcus Koppitz, Antonius Ter Laak, Tim Wintermantel, Bernhard Lindenthal, Nico Bräuer, Gernot Langer, Bernd Buchmann
  • Patent number: 7563924
    Abstract: The present invention relates to 9-chloroprostaglandin derivatives of the general formula I which may be advantageous for the treatment of fertility problems.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: July 21, 2009
    Assignee: Schering Aktiengesellschaft
    Inventors: Bernd Buchmann, Daryl Faulds, William Guilford, Gernot Langer, Judy Li, Bernhard Lindenthal, Werner Skuballa, Luisella Toschi
  • Publication number: 20090042878
    Abstract: The present invention relates to thienopyrimidylamines of the general formula I, to processes for their preparation and to their use for production of pharmaceutical compositions for treatment of disorders and indications connected to the EP2 receptor.
    Type: Application
    Filed: July 10, 2008
    Publication date: February 12, 2009
    Inventors: Nico BRAEUER, Bernd Buchmann, Marcus Koppitz, Olaf Peters, Antonius Ter Laak, Bernhard Lindenthal, Gernot Langer, Tim Wintermantel
  • Publication number: 20090042882
    Abstract: The present invention relates to substituted acetamides of the general formula I, process for their preparation, and the use thereof for the manufacture of pharmaceutical compositions for the treatment of disorders and indications connected with the EP2 receptor.
    Type: Application
    Filed: June 12, 2008
    Publication date: February 12, 2009
    Inventors: Bernd BUCHMANN, Nico Braeuer, Olaf Peters, Knut Eis, Marcus Koppitz, Bernhard Lindenthal, Gernot Langer, Tim Wintermantel, Antonius Ter Laak
  • Publication number: 20090023738
    Abstract: The present invention relates to diaminopyrimidines of the general formula I, process for their preparation, and the use thereof for the manufacture of pharmaceutical compositions for the treatment of disorders and indications connected with the EP2 receptor.
    Type: Application
    Filed: June 19, 2008
    Publication date: January 22, 2009
    Inventors: Nico Braeuer, Bernd Buchmann, Marcus Koppitz, Antonius Ter Laak, Gernot Langer, Bernhard Lindenthal, Olaf Peters, Tim Wintermantel
  • Publication number: 20090023741
    Abstract: The present invention relates to aryl/hetarylamide derivatives of the general formula I, process for their preparation, and the use thereof for the manufacture of pharmaceutical compositions for the treatment of disorders and indications connected with the EP2 receptor.
    Type: Application
    Filed: June 12, 2008
    Publication date: January 22, 2009
    Inventors: Bernd Buchmann, Nico Braeuer, Olaf Peters, Knut Eis, Marcus Koppitz, Bernhard Lindenthal, Gernot Langer, Tim Wintermantel, Antonius Ter Laak
  • Publication number: 20080146576
    Abstract: The present invention relates to phthalazin-1-ylpiperidin-4-ylamides of the general formula I, to processes for their preparation and to their use for producing pharmaceutical compositions for treatment of disorders and indications connected to the EP2 receptor.
    Type: Application
    Filed: September 6, 2007
    Publication date: June 19, 2008
    Inventors: Nico Braeuer, Bernd Buchmann, Koppitz Marcus, Antonius Ter Laak, Gernot Langer, Bernard Lindenthal, Olaf Peters, Tim Wintermantel
  • Publication number: 20080125463
    Abstract: The present invention relates to (het)aryl-3-[(het)arylpiperidin-4-yl]amides, to processes for their preparation and to their use for producing pharmaceutical compositions for treatment of disorders and indications connected to the EP2 receptor.
    Type: Application
    Filed: September 6, 2007
    Publication date: May 29, 2008
    Inventors: Nico Braeuer, Bernd Buchmann, Marcus Koppitz, Antonius Ter Laak, Gernot Langer, Bernhard Lindenthal, Olaf Peters, Tim Wintermantel
  • Publication number: 20080125435
    Abstract: The present invention relates to aryl-3-[(het)aryl-piperidin-4-yl]-thioureas, processes for the production thereof and the use thereof for the production of pharmaceutical agents for the treatment of diseases and indications which are connected with the EP2 receptor.
    Type: Application
    Filed: September 6, 2007
    Publication date: May 29, 2008
    Inventors: Nico Brauer, Bernd Buchmann, Christoph Huwe, Marcus Koppitz, Antonius Ter Laak, Gernot Langer, Bernhard Lindenthal, Olaf Peters, Tim Wintermantel
  • Publication number: 20080004268
    Abstract: The invention relates to compounds of general formula I as well as their production and use as a medication.
    Type: Application
    Filed: August 7, 2007
    Publication date: January 3, 2008
    Inventors: Duy NGUYEN, Anne MENGEL, Martin FRITSCH, Gernot LANGER, Ulf BOEMER, Knut EIS, Bernd MENZENBACH, Bernd BUCHMANN, Seock-Kyu KHIM
  • Publication number: 20070203096
    Abstract: The present invention relates to 9-chloroprostaglandin derivatives of the general formula I which may be advantageous for the treatment of fertility problems.
    Type: Application
    Filed: November 20, 2006
    Publication date: August 30, 2007
    Applicant: Schering Aktiengesellschaft
    Inventors: Bernd Buchmann, Daryl Faulds, William Guilford, Gernot Langer, Judy Li, Bernhard Lindenthal, Werner Skuballa, Luisella Toschi