Patents by Inventor Gerolf Kraus

Gerolf Kraus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6395558
    Abstract: The invention relates to a planar ATR and evanescently exited luminescence optical sensor platform, consisting of a transducer and a recognition layer, wherein changes in the effective refractive index of the recognition layer are converted into a measurable variable in accordance with the integrated-optical light pointer principle. The invention relates also to the use of the method and to the method itself using the sensor platform, for example in label-free biosensory analysis.
    Type: Grant
    Filed: August 5, 1999
    Date of Patent: May 28, 2002
    Assignee: Zeptosens AG
    Inventors: Gert Ludwig Duveneck, Jürg Dübendorfer, Rino Ernst Kunz, Gerolf Kraus
  • Patent number: 6384912
    Abstract: A device has a planar optical waveguide, including a transparent carrier (40) and a wave-guiding layer (41), wherein the waveguide at least has a diffractive element (42) for coupling excitation radiation into the wave-guiding layer. Located on the wave-guiding layer is a further, tightly sealing layer (43) made from a material which, at least at the support surface, is transparent both to the excitation radiation and to the evanescently excited radiation at least to the penetration depth of the evanescent field, and which, for an analysis sample, has, at least in a partial region of the guided excitation radiation, a cavity (45) which is open to the upper side or a cavity (6) which is closed to the upper side and connected by means of an inlet channel (2) and an outlet channel (3).
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: May 7, 2002
    Assignee: Novartis AG
    Inventors: Gerolf Kraus, Michael Pawlak, Gert Ludwig Duveneck, Peter Oroszlan, Andreas Helg, Alfredo Emilio Bruno-Raimondi
  • Publication number: 20010001021
    Abstract: A device comprising a planar optical waveguide, consisting of a transparent carrier (40) and a wave-guiding layer (41), wherein the waveguide at least has a diffractive element (42) for coupling excitation radiation into the wave-guiding layer, and there is located on the wave-guiding layer a further, tightly sealing layer (43) made from a material which, at least at the support surface, is transparent both to the excitation radiation and to the evanescently excited radiation at least to the penetration depth of the evanescent field, and which, for an analysis sample, has, at least in a partial region of the guided excitation radiation, a cavity (45) which is open to the upper side or a cavity (6) which is closed to the upper side and connected by means of an inflow channel (2) and an outflow channel (3), the depth of the cavity corresponding at least to the penetration depth of the evanescent field, and wherein the diffractive element (42) is fully covered by the material of the layer (43) at least in the co
    Type: Application
    Filed: December 22, 2000
    Publication date: May 10, 2001
    Inventors: Gerolf Kraus, Michael Pawlak, Gert Ludwig Duveneck, Peter Oroszlan, Andreas Helg, Alfredo Emilio Bruno-Raimondi
  • Patent number: 6198869
    Abstract: A device comprising a planar optical waveguide, consisting of a transparent carrier (40) and a wave-guiding layer (41), wherein the waveguide at least has a diffractive element (42) for coupling excitation radiation into the wave-guiding layer, and there is located on the wave-guiding layer a further, tightly sealing layer (43) made from a material which, at least at the support surface, is transparent both to the excitation radiation and to the evanescently excited radiation at least to the penetration depth of the evanescent field, and which, for an analysis sample, has, at least in a partial region of the guided excitation radiation, a cavity (45) which is open to the upper side or a cavity (6) which is closed to the upper side and connected by means of an inflow channel (2) and an outflow channel (3), the depth of the cavity corresponding at least to the penetration depth of the evanescent field, and wherein the diffractive element (42) is fully covered by the material of the layer (43) at least in the co
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: March 6, 2001
    Assignee: Novartis AG
    Inventors: Gerolf Kraus, Michael Pawlak, Gert Ludwig Duveneck, Peter Oroszlan, Andreas Helg, Alfredo Emilio Bruno-Raimondi