Patents by Inventor Gerrit BREHM

Gerrit BREHM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3D printed microfluidic mixers and nozzles for crystallography
    Patent number: 10557807
    Abstract: A 3D printed hybrid nozzle device combining a microfluidic mixer with a liquid jet injector that addresses the bottleneck of investigating substrate-initiated biological reaction paths employing serial crystallography with XFELs. The hybrid nozzle provides for injecting aqueous protein crystal jets after fast mixing (<5 ms), reaching reaction time points (e.g., about 10 ms to about 150 ms) suitable to resolve enzyme kinetics.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: February 11, 2020
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Alexandra Ros, Gerrit Brehm, Garrett Nelson, John Spence, Uwe Weierstall, Austin Echelmeier
  • 3D PRINTED MICROFLUIDIC MIXERS AND NOZZLES FOR CRYSTALLOGRAPHY
    Publication number: 20190178822
    Abstract: A 3D printed hybrid nozzle device combining a microfluidic mixer with a liquid jet injector that addresses the bottleneck of investigating substrate-initiated biological reaction paths employing serial crystallography with XFELs. The hybrid nozzle provides for injecting aqueous protein crystal jets after fast mixing (<5 ms), reaching reaction time points (e.g., about 10 ms to about 150 ms) suitable to resolve enzyme kinetics.
    Type: Application
    Filed: May 22, 2018
    Publication date: June 13, 2019
    Inventors: Alexandra ROS, Gerrit BREHM, Garrett NELSON, John SPENCE, Uwe WEIERSTALL, Austin ECHELMEIER