Abstract: The disclosure relates to organosulfur containing compositions, in particular Di-n-butyl thiosulfinate, Di-methyl thiosulfonate, Di-phenyl thiosulfonate, Bis (p-tolyl) thiosulfinate, Di-isopropyl thiosulfinate, Di-benzyl thiosulfinate, Di-benzyl thiosulfonate, S-propyl-4-methylbenzene thiosulfonate, Di-n-propyl thiosulfinate, and Di-n-propyl thiosulfonate. Such compositions are useful for treating infection and reducing or degrading biofilms both in vivo and in vitro. In particular, such compositions are useful in the treatment of biofilm-related disorders, including but not limited to mastitis, digital dermatitis, and chronic wound infections.

Abstract: A method for displaying a warning message in a first vehicle, includes transmitting from a second vehicle a warning and position data relating to a position of the second vehicle to the first vehicle, wherein if, after reception of the warning and of the position data by the first vehicle, it is concluded on the basis of the received position data that the second vehicle can be seen by a driver of the first vehicle in a region of a head-up display of the first vehicle, the warning message is displayed in such a way that the second vehicle is characterized visually for the driver of the first vehicle in the head-up display of the first vehicle.

Abstract: A method for remote programming of a program-controlled device, and a system having an interface to receive program data and a legitimization, as well as a remotely programmable, program-controlled device, which includes a processor and a program memory, are provided. In the method, program data are remotely transmitted from a control station to the interface and buffer-stored there in a buffer store. Subsequently, a legitimization is transmitted from the control station to the interface, and from there to the program-controlled device. The device checks the legitimization and imports the program data from the buffer store if the legitimization check is positive.

Abstract: The present invention relates to nucleic acids and polypeptides encoded thereby, whose expression is modulated in brain microvascular endothelial cells undergoing early dynamic inflammation-induced changes in blood-brain bather functionality. Such polypeptides are referred to as lipopolysaccharide-sensitive (LPSS) polypeptides. These nucleic acids and polypeptides may be useful in methods for controlling blood-brain bather properties in mammals in need of such biological effects. This includes the diagnosis and treatment of disturbances in the blood-brain/retina barrier, brain (including the eye) disorders, as well as peripheral vascular disorders. Additionally, the invention relates to the use of anti-LPSS polypeptide antibodies or ligands as diagnostic probes, as blood-brain barrier targeting agents or as therapeutic agents as well as the use of ligands or modulators of expression, activation or bioactivity of LPSS polypeptides as diagnostic probes, therapeutic agents or drug delivery enhancers.

Abstract: A method for displaying a warning message in a first vehicle, includes transmitting from a second vehicle a warning and position data relating to a position of the second vehicle to the first vehicle, wherein if, after reception of the warning and of the position data by the first vehicle, it is concluded on the basis of the received position data that the second vehicle can be seen by a driver of the first vehicle in a region of a head-up display of the first vehicle, the warning message is displayed in such a way that the second vehicle is characterized visually for the driver of the first vehicle in the head-up display of the first vehicle.

Abstract: The present invention relates to nucleic acids and polypeptides encoded thereby, whose expression is modulated in brain microvascular endothelial cells undergoing early dynamic inflammation-induced changes in blood-brain barrier functionality. Such polypeptides are referred to as lipopolysaccharide-sensitive (LPSS) polypeptides herein. These nucleic acids and polypeptides may be useful in methods for controlling blood-brain barrier properties in mammals in need of such biological effects. This includes the diagnosis and treatment of disturbances in the blood-brain/retina barrier, brain (including the eye) disorders, as well as peripheral vascular disorders. Additionally, the invention relates to the use of anti-LPSS polypeptide antibodies or ligands as diagnostic probes, as blood-brain barrier targeting agents or as therapeutic agents as well as the use of ligands or modulators of expression, activation or bioactivity of LPSS polypeptides as diagnostic probes, therapeutic agents or drug delivery enhancers.

Abstract: In a method for operating a heads-up display system of a vehicle, the roadway state of the roadway to be traveled by the vehicle is checked using at least one suitable sensor, and a warning message is displayed at a location on the windshield in the case of detection of a critical roadway state, the location of the warning message corresponding to the dangerous, driving area of the roadway as viewed from the driver's perspective.

Abstract: The invention relates to a method for preparing models of technical devices, wherein each technical device comprises units that are connected to each other by means of connection points, wherein, when performing the method, at least one structure made of units connected to each other by means of connection points comprising similarities for all technical devices is integrated and automatically described as at least one mutual module (8) for all models.

Abstract: The invention relates to a method for describing a behavior of a technical apparatus, which has a number of units, a system graph (8), which comprises a number of levels, being automatically generated for the technical apparatus, in each case a k+1th level being subordinate to a kth level and at least one subordinate unit in the k+1th level being associated with a superior unit from the kth level, a technical behavior of the at least one subordinate unit being summarized in each superior unit. Furthermore, the invention relates to a method for the diagnosis of a technical apparatus.

Abstract: A method for starting up an application in a mobile data processing device, for the operation of which an information database is required in the device. The inventive method includes the following steps: a) provision of a permanent portion and a temporary portion of the information database; b) wire-bound transmission of the permanent portion from a central server to an intermediate server; c) transmission of the permanent portion from the intermediate server to the device via a first transmission path and storage in the device; d) transmission of the temporary portion via wireless communication, the wireless communication representing a second transmission path that is distinct from the first transmission path; and e) execution of the application.

Abstract: A method and arrangement for installing a software module in a device are provided, an operating system and a hardware-independent software environment such as a Java environment may be operated on the device and new software modules for the operating system may be installed via an interface with the software environment and an installation manager in the operating system. For this purpose, the software environment provides data to the installation manager via the installation interface. The installation manager, shielded from the software environment, then carries out the installation of the software module.

Abstract: A method for starting up an application in a mobile data processing device, for the operation of which an information database is required in the device. The inventive method includes the following steps: a) provision of a permanent portion and a temporary portion of the information database; b) wire-bound transmission of the permanent portion from a central server to an intermediate server; c) transmission of the permanent portion from the intermediate server to the device via a first transmission path and storage in the device; d) transmission of the temporary portion via wireless communication, the wireless communication representing a second transmission path that is distinct from the first transmission path; and e) execution of the application.

Abstract: A method for supplying internal information relevant for performing a diagnosis, of an application available in a vehicle and running on a service gateway, in which a defined uniform application diagnostic interface, via which communication with the service gateway is made possible, is provided in the application.

Abstract: A method for automatically updating software which is used for updating software which is running on a system, by using new software modules, these software modules first being tested, and application modules then being derived from these software modules. The actual new function is implemented by the application modules. The software modules may be received advantageously over a wireless interface. The method according to the present invention is particularly suited for applications where software is used in a motor vehicle. The application module is usually derived from the software module on the basis of the principle of inheritance. The software module is tested by a call instruction using test parameters.

Abstract: The present invention relates to nucleic acids and polypeptides encoded thereby, whose expression is modulated in brain microvascular endothelial cells undergoing early dynamic inflammation-induced changes in blood-brain barrier functionality. Such polypeptides are referred to as lipopolysaccharide-sensitive (LPSS) polypeptides herein. These nucleic acids and polypeptides may be useful in methods for controlling blood-brain barrier properties in mammals in need of such biological effects. This includes the diagnosis and treatment of disturbances in the blood-brain/retina barrier, brain (including the eye) disorders, as well as peripheral vascular disorders. Additionally, the invention relates to the use of anti-LPSS polypeptide antibodies or ligands as diagnostic probes, as blood-brain barrier targeting agents or as therapeutic agents as well as the use of ligands or modulators of expression, activation or bioactivity of LPSS polypeptides as diagnostic probes, therapeutic agents or drug delivery enhancers.

Abstract: A method for remote programming of a program-controlled device, and a system having an interface to receive program data and a legitimization, as well as a remotely programmable, program-controlled device, which includes a processor and a program memory, are provided. In the method, program data are remotely transmitted from a control station to the interface and buffer-stored there in a buffer store. Subsequently, a legitimization is transmitted from the control station to the interface, and from there to the program-controlled device. The device checks the legitimization and imports the program data from the buffer store if the legitimization check is positive.

Abstract: A method for automatically updating software which is used for updating software which is running on a system, by using new software modules, these software modules first being tested, and application modules then being derived from these software modules. The actual new function is implemented by the application modules. The software modules may be received advantageously over a wireless interface. The method according to the present invention is particularly suited for applications where software is used in a motor vehicle. The application module is usually derived from the software module on the basis of the principle of inheritance. The software module is tested by a call instruction using test parameters.