Patents by Inventor Gerrit Johan Ossenkoppele

Gerrit Johan Ossenkoppele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Leukemic stem cell markers
    Publication number: 20160305945
    Abstract: The present invention relates to a method for identifying Leukemic stem cells (LSC), based on measurement of the presence of a specific set of markers. The invention further relates to a container for use in performing the method. Also provided is application of the method for predicting response to therapy and/or chance of relapse of Acute Myeloid Leukemia, and application of the method in the context of screening for compounds that specifically eradicate Leukemic cells and not benign cells.
    Type: Application
    Filed: December 2, 2014
    Publication date: October 20, 2016
    Inventors: Gerrit Johan OSSENKOPPELE, Gerrit Jan SCHUURHUIS, Wendelien ZEIJLEMAKER
  • METHOD FOR PREDICTING TYROSINE KINASE INHIBITOR (TKI) RESISTANCE IN PATIENTS SUFFERING FROM CHRONIC MYELOGENOUS LEUKEMIA (CML)
    Publication number: 20130217055
    Abstract: The present invention relates to a method for determining or predicting the response of a patient diagnosed with chronic myelogenous leukaemia (CML) to treatment with a tyrosine kinase inhibitor. More specifically, the present invention provides methods which measure kinase activity by studying phosphorylation levels and profiles and inhibitions thereof thereby diagnosing CML patients resistant to treatment with Imatinib.
    Type: Application
    Filed: October 17, 2011
    Publication date: August 22, 2013
    Applicant: PamGene B.V.
    Inventors: Pieter Jacob Boender, Adriana Van Den Berg, Robby Ruijtenbeek, Jeroen Johannes Wilhelmus Maria Janssen, Gerrit Johan Ossenkoppele