Patents by Inventor Gerrit Prop

Gerrit Prop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for reducing reflex tachycardia in the treatment of hypertension employing a combination of a diazacyclopentene derivative and a pyridazinone derivative
    Patent number: 4746660
    Abstract: The invention relates to a new process for the treatment of hypertension and thromboembolic diseases in humans by simultaneous administration of (.+-.)- or (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene hydrochloride on the one side, and 4,5-dihydro-6-[4-(1-imidazolyl)-phenyl]-5-methyl-3(2H)-pyridazinone or 4,5-dihydro-6-[4-(1-imidazolyl)-thien-2-yl]-5-methyl-3(2H)-pyridazinone, on the other side, as the active substances.
    Type: Grant
    Filed: January 21, 1987
    Date of Patent: May 24, 1988
    Assignee: A. Natternabb & CIE GmbH
    Inventors: Jurgen Biedermann, Harald Borbe, Erich Graf, Gerd Hilboll, Gerrit Prop
  • Imidazole group containing 2(1H)-pyridones and method for treating heart insufficiencies in humans
    Patent number: 4699914
    Abstract: The present invention is directed to new, an imidazole group containing 2(1H)-pyridones of formula I ##STR1## salts thereof and process for treating congestive heart failure in humans.
    Type: Grant
    Filed: September 3, 1985
    Date of Patent: October 13, 1987
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Gerd Hilboll, Ille-Stephanie Doppelfeld, Gerrit Prop
  • Substituted 6-(thien-2-yl)-3(2H)-pyridazinones
    Patent number: 4667033
    Abstract: The invention refers to substituted 6-(thien-2-yl)-3(2H)-pyridazinones of Formula I ##STR1##
    Type: Grant
    Filed: June 8, 1984
    Date of Patent: May 19, 1987
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Gerd Hilboll, Sigurd Leyck, Gerrit Prop
  • Process for reducing reflex tachycardia in the treatment of hypertension employing a combination of a diazacyclopentene derivative and a pyridazinone derivative
    Patent number: 4661487
    Abstract: The invention relates to a new process for the treatment of hypertension and thromboembolic diseases in humans by simultaneous administration of (.+-.)- or (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene hydrochloride on the one side, and 4,5-dihydro-6-[4-(1-imidazolyl)-phenyl]-5-methyl-3(2H)-pyridazinone or 4,5-dihydro-6-[4-(1-imidazolyl)-thien-2-yl]-5-methyl-3(2H)-pyridazinone, on the other side, as the active substances.
    Type: Grant
    Filed: February 26, 1985
    Date of Patent: April 28, 1987
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Jurgen Biedermann, Harald Borbe, Erich Graf, Gerd Hilboll, Gerrit Prop
  • 1,4,5-triphenylimidazol-2-yl mercapto alkanoic acids, useful against inflammation and diseases responding to lipid lowering
    Patent number: 4654358
    Abstract: The invention is related to imidazol-2-yl mercapto alkanoic acids having the formula I ##STR1## process for the treatment of humans suffering from inflammatory diseases or diseases in relation with the lipid metabolism.
    Type: Grant
    Filed: June 25, 1984
    Date of Patent: March 31, 1987
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Gerrit Prop, Helmut Wetzig
  • Imidazolylalkylthienyl tetrahydropyridazines and processes for their use
    Patent number: 4643998
    Abstract: The invention relates to new imidazolylalkylthienyltetrahydropyridazines of the general formula I ##STR1## their acid addition salts as well as processes for their use in the treatment of cardiovascular and/or thromboembolic illnesses in humans.
    Type: Grant
    Filed: October 26, 1983
    Date of Patent: February 17, 1987
    Assignee: A. Natterman & Cie GmbH
    Inventors: Gerd Hilboll, Gerrit Prop, Harald Borbe, Josef P. Lohr, Ille-Stephanie Doppelfeld
  • 1-O-alkyl-3-amino-propan-1.2-diol-2-O-phospholipids
    Patent number: 4599205
    Abstract: The invention is related to 1-O-alkyl-3-amino-propan-1.
    Type: Grant
    Filed: June 25, 1984
    Date of Patent: July 8, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Michael J. Parnham, Gerrit Prop
  • Substituted aminoalkanol phospholipids
    Patent number: 4565659
    Abstract: The invention concerns new substituted aminoalkanol phospholipids of the general Formula I ##STR1## and methods for the treatment of humans suffering from high blood-pressure (hypertension), from inflammatory illnesses, from tumors and/or atherosclerosis by administering medicaments containing such a compound as well as methods for plant protections.
    Type: Grant
    Filed: October 18, 1983
    Date of Patent: January 21, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Harald Borbe, Gerrit Prop, Ferdinand Wirtz-Peitz, Ille-Stephanie Doppelfeld, Michael J. Parnham
  • O-Alkyl-O-carbamoylglycerophosphocholines and the use for treating hypertension
    Patent number: 4552869
    Abstract: The present invention relates to new O-alkyl-O-carbamoylglycerophosphocholines of the general formulae I or II ##STR1## and processes for treating human beings suffering from diseases caused by hypertension by administering one or several of the above compounds.
    Type: Grant
    Filed: June 15, 1984
    Date of Patent: November 12, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Hans Betzing, Gerrit Prop, Ottfried Zierenberg
  • Method of treating high blood pressure using 6-[4-(1-imidazolyl)-phenyl]-5-methyl-3-oxo-tetrahydropyridazines
    Patent number: 4551455
    Abstract: The present invention relates to new 6-[Imidazolyl-phenyl]-5-methyl-3-oxo-tetrahydropyridazines of the general formula I ##STR1## as well as their acid addition salts, methods for their use, and pharmaceutical preparations containing them.
    Type: Grant
    Filed: March 25, 1983
    Date of Patent: November 5, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Gerd Hilboll, Ille-Stephanie Doppelfeld, Gerrit Prop
  • Process for producing (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene
    Patent number: 4518783
    Abstract: This invention relates to processes for producing the (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and to pharmaceutically acceptable acid addition salts thereof and the method for lowering the blood pressure in human beings suffering from increased blood pressure, using these compounds.
    Type: Grant
    Filed: May 27, 1983
    Date of Patent: May 21, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Jurgen Biedermann, Gerrit Prop, Ille-Stephanie Doppelfeld
  • Triphenylimidazolyloxyalkanoic acids and their derivatives and a process for the treatment of thromboembolic, inflammatory and/or atheriosclerotic diseases
    Patent number: 4460598
    Abstract: The invention relates to new triphenylimidazolyloxyalkanoic acids of the general formula I ##STR1## and a process for the treatment of thromboembolic, inflammatory and/or atherosclerotic diseases in humans by using the same.
    Type: Grant
    Filed: July 25, 1983
    Date of Patent: July 17, 1984
    Assignee: A. Nattermann & Cie GMBH
    Inventors: Hans-Heiner Lautenschlager, Andre Welter, Gerd Hilboll, Johannes Winkelmann, Gerrit Prop, Axel Brekle, Ottfried Zierenberg
  • (+)-2-[1-(2,6-Dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and the method for the treatment of human beings suffering from nervous disarrangements, in particular migraine
    Patent number: 4443464
    Abstract: This invention relates to (+)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and to pharmaceutically acceptable acid addition salts thereof and the method for the treatment of human beings suffering from nervous disarrangements, in particular migraine, using these compounds.
    Type: Grant
    Filed: April 13, 1982
    Date of Patent: April 17, 1984
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Jurgen Biedermann, Gerrit Prop, Ille-Stephanie Doppelfeld