Abstract: The disclosure relates to devices and methods for the treatment of edema which devices use an intravascular edema pump with an anticoagulant. The invention provides devices and methods for treating edema that use an indwelling catheter to place an impeller in a blood vessel of a patient, near an outlet of a lymphatic duct. Operating the impeller creates a local depression in blood pressure, which promotes drainage of lymph from the lymphatic system. The catheter is also used to release an anticoagulant such as heparin to wash and lubricate the impeller. Specifically, the anticoagulant inhibits clotting, hemolysis, or thrombosis from occurring and interfering with smooth operation of the impeller.

Abstract: This invention relates to a set screw comprising a shank having external threads and a work-engaging end portion integrally formed at one end of the shank. The work-engaging end portion has a frustohemispherical outer surface comprising a plurality of circumferentially spaced serrations in the form of teeth. Each of the teeth comprises a ramp extending outwardly from a root to a crest thereof with the ramp being inclined in a direction which is opposite to the direction of rotation of engaging the set screw in a workpiece. A cavity is formed in the outer extremity of the work-engaging end portion. The cavity cooperates with the frustohemispherical outer surface to form therebetween an annular wedge. The work-engaging end portion can be readily formed by a forging process.